Symptom Information: Sort according to HPO 

1
 (HPO:0001761) Pes cavus Very frequent [IBIS] 100% (n=5) 21419568 IBIS 225 / 7739
2
 (HPO:0002064) Spastic gait Very frequent [IBIS] 100% (n=6) 17205300 IBIS 46 / 7739
3
 (HPO:0007340) Lower limb muscle weakness Very frequent [IBIS] 100% (n=5) 21419568 IBIS 61 / 7739
4
 (HPO:0004302) Functional motor problems Very frequent [IBIS] 100% (n=6) 17205300 IBIS 2 / 7739
5
 (HPO:0002395) Lower limb hyperreflexia Very frequent [IBIS] 100% (n=6) 17205300 IBIS 26 / 7739
6
 (HPO:0011448) Ankle clonus Very frequent [IBIS] 100% (n=5) 21419568 IBIS 31 / 7739
7
 (HPO:0007083) Hyperactive patellar reflex Very frequent [IBIS] 100% (n=5) 21419568 IBIS 4 / 7739
8
 (HPO:0003438) Absent Achilles reflex Very frequent [IBIS] 100% (n=5) 21419568 IBIS 9 / 7739
9
 (HPO:0007210) Lower limb amyotrophy Very frequent [IBIS] 100% (n=5) 21419568 IBIS 7 / 7739
10
 (HPO:0001258) Spastic paraplegia Very frequent [IBIS] 14508710 IBIS 97 / 7739
11
 (HPO:0002061) Lower limb spasticity Very frequent [IBIS] 17205300 IBIS 56 / 7739
12
 (HPO:0002191) Progressive spasticity Very frequent [IBIS] 17205300 IBIS 12 / 7739
13
 (HPO:0000012) Urinary urgency Frequent [IBIS] 80% (n=5) 21419568 IBIS 35 / 7739
14
 (HPO:0003487) Babinski sign Frequent [IBIS] 75% (n=4) 17205300 IBIS 179 / 7739
15
 (HPO:0002354) Memory impairment Frequent [IBIS] 67% (n=6) 17205300 IBIS 63 / 7739
16
 (HPO:0002166) Impaired vibration sensation in the lower limbs Frequent [IBIS] 60% (n=5) 21419568 IBIS 26 / 7739
17
 (HPO:0007350) Hyperreflexia in upper limbs Frequent [IBIS] 60% (n=5) 21419568 IBIS 5 / 7739
18
 (HPO:0011449) Knee clonus Frequent [IBIS] 40% (n=5) 21419568 IBIS 10 / 7739
19
 (HPO:0030237) Hand muscle weakness Frequent [IBIS] 40% (n=5) 21419568 IBIS 4 / 7739
20
 (HPO:0007108) Demyelinating peripheral neuropathy Frequent [IBIS] 40% (n=5) 21419568 IBIS 8 / 7739
21
 (HPO:0001250) Seizures Frequent [IBIS] 36% (n=14) 15711826 IBIS 1245 / 7739
22
 (HPO:0001347) Hyperreflexia Frequent [IBIS] 21419568 IBIS 363 / 7739
23
 (HPO:0001337) Tremor Occasional [IBIS] Rare [HPO:skoehler] 21% (n=14) 15711826 IBIS 200 / 7739
24
 (HPO:0000016) Urinary retention Occasional [IBIS] 17% (n=6) 17205300 IBIS 7 / 7739
25
 (HPO:0100515) Pollakisuria Occasional [IBIS] 17% (n=6) 17205300 IBIS 12 / 7739
26
 (HPO:0000505) Visual impairment Occasional [IBIS] 17% (n=6) 17205300 IBIS 297 / 7739
27
 (HPO:0000722) Obsessive-compulsive behavior Occasional [IBIS] 17% (n=6) 17205300 IBIS 35 / 7739
28
 (HPO:0002169) Clonus 21419568 IBIS 37 / 7739
29
 (HPO:0003676) Progressive disorder 17205300 IBIS 148 / 7739
30
 (HPO:0001260) Dysarthria 24954637 IBIS 329 / 7739
31
 (HPO:0001271) Polyneuropathy 24954637 IBIS 56 / 7739
32
 (HPO:0100543) Cognitive impairment 24954637 IBIS 230 / 7739
33
 (HPO:0012179) Craniofacial dystonia 24954637 IBIS 4 / 7739
34
 (HPO:0006006) Hypotrophy of the small hand muscles 24954637 IBIS 4 / 7739
35
 (HPO:0006986) Upper limb spasticity 24954637 IBIS 15 / 7739