Symptom Information: Sort according to HPO 

1
 (HPO:0000083) Renal insufficiency Occasional [Orphanet] 232 / 7739
2
 (HPO:0000112) Nephropathy Occasional [Orphanet] 92 / 7739
3
 (HPO:0000140) Abnormality of the menstrual cycle Occasional [Orphanet] 7 / 7739
4
 (HPO:0000138) Ovarian cyst Occasional [Orphanet] occasional [HPO] 25 / 7739
5
 (HPO:0000147) Polycystic ovaries Occasional [Orphanet] 18 / 7739
6
 (HPO:0008675) Enlarged polycystic ovaries Occasional [Orphanet] occasional [HPO] 14 / 7739
7
 (HPO:0000163) Abnormality of the oral cavity Occasional [Orphanet] 37 / 7739
8
 (HPO:0000303) Mandibular prognathia Very frequent [Orphanet] 179 / 7739
9
 (HPO:0000336) Prominent supraorbital ridges Very frequent [Orphanet] 45 / 7739
10
 (HPO:0000819) Diabetes mellitus Very frequent [Orphanet] 131 / 7739
11
 (HPO:0000826) Precocious puberty Frequent [Orphanet] 42 / 7739
12
 (HPO:0100000) Early onset of sexual maturation Frequent [Orphanet] typical [HPO] 9 / 7739
13
 (HPO:0000842) Hyperinsulinemia Very frequent [Orphanet] 39 / 7739
14
 (HPO:0000845) Growth hormone excess Frequent [Orphanet] 18 / 7739
15
 (HPO:0000831) Insulin-resistant diabetes mellitus Very frequent [Orphanet] hallmark [HPO] 22 / 7739
16
 (HPO:0000855) Insulin resistance Very frequent [Orphanet] 32 / 7739
17
 (HPO:0000956) Acanthosis nigricans Very frequent [Orphanet] 54 / 7739
18
 (HPO:0000975) Hyperhidrosis Frequent [Orphanet] 64 / 7739
19
 (HPO:0000998) Hypertrichosis Frequent [Orphanet] 52 / 7739
20
 (HPO:0001007) Hirsutism Frequent [Orphanet] typical [HPO] 91 / 7739
21
 (HPO:0002230) Generalized hirsutism Frequent [Orphanet] typical [HPO] 32 / 7739
22
 (HPO:0004554) Generalized hypertrichosis Frequent [Orphanet] typical [HPO] 30 / 7739
23
 (HPO:0001000) Abnormality of skin pigmentation Frequent [Orphanet] 105 / 7739
24
 (HPO:0001169) Broad palm Very frequent [Orphanet] hallmark [HPO] 43 / 7739
25
 (HPO:0001176) Large hands Very frequent [Orphanet] 43 / 7739
26
 (HPO:0001230) Broad metacarpals Very frequent [Orphanet] hallmark [HPO] 17 / 7739
27
 (HPO:0001394) Cirrhosis Occasional [Orphanet] 102 / 7739
28
 (HPO:0001397) Hepatic steatosis Occasional [Orphanet] 75 / 7739
29
 (HPO:0001399) Hepatic failure Frequent [Orphanet] 80 / 7739
30
 (HPO:0001639) Hypertrophic cardiomyopathy Frequent [Orphanet] 137 / 7739
31
 (HPO:0001677) Coronary artery disease Occasional [Orphanet] 58 / 7739
32
 (HPO:0001733) Pancreatitis Occasional [Orphanet] 46 / 7739
33
 (HPO:0001769) Broad foot Very frequent [Orphanet] 31 / 7739
34
 (HPO:0001833) Long foot Very frequent [Orphanet] hallmark [HPO] 33 / 7739
35
 (HPO:0002092) Pulmonary hypertension Occasional [Orphanet] 109 / 7739
36
 (HPO:0002119) Ventriculomegaly Occasional [Orphanet] 253 / 7739
37
 (HPO:0002240) Hepatomegaly Very frequent [Orphanet] 467 / 7739
38
 (HPO:0002757) Recurrent fractures Occasional [Orphanet] 47 / 7739
39
 (HPO:0003119) Abnormality of lipid metabolism Very frequent [Orphanet] 60 / 7739
40
 (HPO:0003712) Skeletal muscle hypertrophy Very frequent [Orphanet] 42 / 7739
41
 (HPO:0003720) Generalized muscle hypertrophy Very frequent [Orphanet] hallmark [HPO] 8 / 7739
42
 (HPO:0100293) Muscle fiber hypertrophy Very frequent [Orphanet] hallmark [HPO] 6 / 7739
43
 (HPO:0004233) Advanced ossification of carpal bones Very frequent [Orphanet] hallmark [HPO] 14 / 7739
44
 (HPO:0005616) Accelerated skeletal maturation Very frequent [Orphanet] 46 / 7739
45
 (HPO:0003477) Peripheral axonal neuropathy Occasional [Orphanet] occasional [HPO] 62 / 7739
46
 (HPO:0007178) Motor polyneuropathy Occasional [Orphanet] occasional [HPO] 31 / 7739
47
 (HPO:0009830) Peripheral neuropathy Occasional [Orphanet] 206 / 7739
48
 (HPO:0010978) Abnormality of immune system physiology Occasional [Orphanet] 148 / 7739
49
 (HPO:0100543) Cognitive impairment Frequent [Orphanet] 230 / 7739
50
 (HPO:0100578) Lipoatrophy Very frequent [Orphanet] 30 / 7739
51
 (HPO:0012062) Bone cyst Frequent [Orphanet] 19 / 7739
52
 (HPO:0100820) Glomerulopathy Occasional [Orphanet] 46 / 7739
53
 (HPO:0001658) Myocardial infarction Occasional [Orphanet] 30 / 7739
54
 (HPO:0001681) Angina pectoris Occasional [Orphanet] 22 / 7739
55
 (HPO:0001760) Abnormality of the foot Very frequent [Orphanet] 96 / 7739
56
 (HPO:0001595) Abnormality of the hair Frequent [Orphanet] 89 / 7739
57
 (HPO:0100545) Arterial stenosis Occasional [Orphanet] 22 / 7739
58
 (HPO:0002718) Recurrent bacterial infections Occasional [Orphanet] 75 / 7739
59
 (HPO:0002719) Recurrent infections Occasional [Orphanet] 107 / 7739
60
 (HPO:0002721) Immunodeficiency Occasional [Orphanet] 97 / 7739
61
 (HPO:0001410) Decreased liver function Frequent [Orphanet] 59 / 7739
62
 (HPO:0002155) Hypertriglyceridemia Very frequent [Orphanet] 67 / 7739
63
 (HPO:0003077) Hyperlipidemia Very frequent [Orphanet] 37 / 7739
64
 (HPO:0003124) Hypercholesterolemia Very frequent [Orphanet] 53 / 7739
65
 (Orphanet:29420) Storage liver disease Very frequent [Orphanet] 5 / 7739
66
 (HPO:0000157) Abnormality of the tongue Occasional [Orphanet] 6 / 7739
67
 (HPO:0000168) Abnormality of the gingiva Occasional [Orphanet] 51 / 7739
68
 (HPO:0011830) Abnormality of oral mucosa Occasional [Orphanet] 47 / 7739
69
 (HPO:0002659) Increased susceptibility to fractures Occasional [Orphanet] 110 / 7739
70
 (MedDRA:10063750) Life expectancy shortened Occasional [Orphanet] 4 / 7739
71
 (HPO:0001072) Thickened skin Very frequent [Orphanet] 87 / 7739
72
 (HPO:0100607) Dysmenorrhea Occasional [Orphanet] 8 / 7739
73
 (HPO:0100608) Metrorrhagia Occasional [Orphanet] 5 / 7739
74
 (HPO:0000132) Menorrhagia Occasional [Orphanet] 40 / 7739
75
 (HPO:0007552) Abnormal subcutaneous fat tissue distribution Very frequent [Orphanet] 12 / 7739
76
 (HPO:0009064) Generalized lipodystrophy Very frequent [Orphanet] 17 / 7739
77
 (HPO:0009125) Lipodystrophy Very frequent [Orphanet] 54 / 7739
78
 (HPO:0001249) Intellectual disability Frequent [Orphanet] 1089 / 7739
79
 (HPO:0001263) Global developmental delay Frequent [Orphanet] 853 / 7739
80
 (HPO:0001270) Motor delay Frequent [Orphanet] 322 / 7739
81
 (HPO:0001328) Specific learning disability Frequent [Orphanet] 114 / 7739
82
 (HPO:0001644) Dilated cardiomyopathy Frequent [Orphanet] 141 / 7739
83
 (HPO:0000137) Abnormality of the ovary Occasional [Orphanet] 41 / 7739