Palmoplantar hyperkeratosis

Symptom Information:

Symptom ID: HPO:0000972
Synonyms:
Hyperkeratosis of palms and soles [HPO:0000972]
Hyperkeratosis of the palms and soles [HPO:0000972]
Palmoplantar keratoses [HPO:0000972]
Palmoplantar keratosis [HPO:0000972]
Thick palms and soles [HPO:0000972]
Thickened palms and soles [HPO:0000972]
Palmoplantar Keratosis [Orphanet:23100]
Hyperkeratosis of palms and soles [OMIM:Hyperkeratosis of palms and soles]
Hyperkeratosis of the palms and soles [OMIM:Hyperkeratosis of the palms and soles]
Palmoplantar hyperkeratosis [OMIM:Palmoplantar hyperkeratosis]
Palmoplantar keratoses [OMIM:Palmoplantar keratoses]
Palmoplantar keratosis [OMIM:Palmoplantar keratosis]
Thickened palms and soles [OMIM:Thickened palms and soles]
Palmoplantar hyperkeratosis/keratoderma [Orphanet:23100]
Palmoplantar keratoderma [Orphanet:23100]
Palmoplantar keratoderma [MedDRA:10033554]
Keratosis palmaris [MedDRA:10033554]
Tylosis palmaris [MedDRA:10033554]
Hyperkeratosis palmaris and plantaris [MedDRA:10033554]
Keratosis plantaris [MedDRA:10033554]
Keratosis palmaris [OMIM:Keratosis palmaris]
Keratosis plantaris [OMIM:Keratosis plantaris]
Palmoplantar keratoderma (in some patients) [OMIM:Palmoplantar keratoderma (in some patients)]
Quality:
Cross references:
HPO:0000982 "Palmoplantar keratoderma" [Orphanet:23100]
HPO:0007447 "Diffuse palmoplantar hyperkeratosis" [Orphanet:23100]
Orphanet:23100 "Palmoplantar hyperkeratosis/keratoderma" [Orphanet:23100]
OMIM: "Hyperkeratosis of palms and soles" [OMIM:Hyperkeratosis of palms and soles]
OMIM: "Hyperkeratosis of the palms and soles" [OMIM:Hyperkeratosis of the palms and soles]
OMIM: "Palmoplantar hyperkeratosis" [OMIM:Palmoplantar hyperkeratosis]
OMIM: "Palmoplantar keratoses" [OMIM:Palmoplantar keratoses]
OMIM: "Palmoplantar keratosis" [OMIM:Palmoplantar keratosis]
OMIM: "Thickened palms and soles" [OMIM:Thickened palms and soles]
OMIM: "Keratosis palmaris" [OMIM:Keratosis palmaris]
OMIM: "Keratosis plantaris" [OMIM:Keratosis plantaris]
OMIM: "Palmoplantar keratoderma (in some patients)" [OMIM:Palmoplantar keratoderma (in some patients)]
UMLS:C0022596 "Palmoplantar Keratosis" [Orphanet:23100]
Is a (Direct Parents):
HPO         Abnormality of the palm
HPO         Abnormality of the plantar skin of foot
MedDRA Hyperkeratoses
HPO         Palmar hyperkeratosis
Orphanet Abnormality of the skin
HPO         Plantar hyperkeratosis
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of the skin(HPO:0000951)
             Generalized abnormality of skin(HPO:0011354)
                Abnormality of skin morphology(HPO:0011121)
                   Thickened skin(HPO:0001072)
                      Epidermal thickening(HPO:0011368)
                         Hyperkeratosis(HPO:0000962)
                            Palmar hyperkeratosis(HPO:0010765)
                               Palmoplantar hyperkeratosis(HPO:0000972)
                            Plantar hyperkeratosis(HPO:0007556)
                               Palmoplantar hyperkeratosis(HPO:0000972)
             Regional abnormality of skin(HPO:0011356)
                Abnormality of the plantar skin of foot(HPO:0100872)
                   Palmoplantar hyperkeratosis(HPO:0000972)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal appendicular skeleton morphology(HPO:0011844)
                Abnormality of limb bone morphology(HPO:0002813)
                   Abnormality of the upper limb(HPO:0002817)
                      Abnormality of the hand(HPO:0001155)
                         Abnormality of the palm(HPO:0100871)
                            Palmoplantar hyperkeratosis(HPO:0000972)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Cornification and dystrophic skin disorders(MedDRA:10011063)
       Hyperkeratoses(MedDRA:10020648)
          Palmoplantar hyperkeratosis(HPO:0000972)
Database Frequency: 41 / 7739
Resource:

All diseases associated with this symptom:

ACHALASIA-ADDISONIANISM-ALACRIMA SYNDROME (OMIM:231550)
ANHIDROSIS, FAMILIAL GENERALIZED, WITH ABNORMAL OR ABSENT SWEAT GLANDS (OMIM:206600)
Annular epidermolytic ichthyosis (Orphanet:281139)
Arrhythmogenic right ventricular dysplasia, familial, 11 (OMIM:610476)
Autosomal dominant palmoplantar keratoderma and congenital alopecia (Orphanet:1010)
Autosomal recessive palmoplantar keratoderma and congenital alopecia (Orphanet:1366)
Buschke-Ollendorff syndrome (Orphanet:1306)
COWDEN SYNDROME 5 (OMIM:615108)
COWDEN SYNDROME 6 (OMIM:615109)
Congenital reticular ichthyosiform erythroderma (Orphanet:281190)
Cowden syndrome (Orphanet:201)
Cranio-osteoarthropathy (Orphanet:1525)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 2 (OMIM:613989)
Dermatopathia pigmentosa reticularis (Orphanet:86920)
EPIDERMOLYTIC HYPERKERATOSIS (OMIM:113800)
Epidermolysis bullosa simplex with muscular dystrophy (Orphanet:257)
Epidermolysis bullosa simplex, Dowling-Meara type (Orphanet:79396)
Epidermolytic ichthyosis (Orphanet:312)
Epidermolytic palmoplantar keratoderma (Orphanet:2199)
Familial isolated dilated cardiomyopathy (Orphanet:154)
Generalized epidermolysis bullosa simplex, non-Dowling-Meara type (Orphanet:79399)
Hereditary acrokeratotic poikiloderma of Kindler-Weary (Orphanet:306539)
Hidrotic ectodermal dysplasia (Orphanet:189)
Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome (Orphanet:363523)
ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 5 (OMIM:604777)
Keratosis palmaris et plantaris - clinodactyly (Orphanet:86919)
Lhermitte-Duclos disease (Orphanet:65285)
PACHYONYCHIA CONGENITA 1 (OMIM:167200)
PACHYONYCHIA CONGENITA 2 (OMIM:167210)
PALMOPLANTAR KERATODERMA, MUTILATING, WITH PERIORIFICIAL KERATOTICPLAQUES, X-LINKED (OMIM:300918)
Pachyonychia congenita (Orphanet:2309)
Palmoplantar keratoderma-deafness syndrome (Orphanet:2202)
Papillon-Lefèvre syndrome (Orphanet:678)
Paraplegia - intellectual deficit - hyperkeratosis (Orphanet:2824)
Proteus-like syndrome (Orphanet:2969)
Rosselli-Gulienetti syndrome (Orphanet:90339)
Stern-Lubinsky-Durrie syndrome (Orphanet:3194)
Triple A syndrome (Orphanet:869)
Tyrosinemia type 2 (Orphanet:28378)
Zlotogora-Ogur syndrome (Orphanet:3253)
Zunich-Kaye syndrome (Orphanet:3474)