Diffuse palmoplantar hyperkeratosis

Symptom Information:

Symptom ID: HPO:0007447
Synonyms:
Hyperkeratosis, diffuse palmoplantar [HPO:0007447]
Palmoplantar hyperkeratosis [Orphanet:23100]
Palmoplantar Keratosis [Orphanet:23100]
Palmoplantar hyperkeratosis/keratoderma [Orphanet:23100]
Palmoplantar keratoderma [Orphanet:23100]
Palmoplantar keratoderma [MedDRA:10033554]
Keratosis palmaris [MedDRA:10033554]
Tylosis palmaris [MedDRA:10033554]
Hyperkeratosis palmaris and plantaris [MedDRA:10033554]
Keratosis plantaris [MedDRA:10033554]
Hyperkeratosis, diffuse palmoplantar (tylosis) [OMIM:Hyperkeratosis, diffuse palmoplantar (tylosis)]
Keratosis palmaris [OMIM:Keratosis palmaris]
Keratosis plantaris [OMIM:Keratosis plantaris]
Palmoplantar keratoderma (in some patients) [OMIM:Palmoplantar keratoderma (in some patients)]
Quality:
Cross references:
HPO:0000982 "Palmoplantar keratoderma" [Orphanet:23100]
HPO:0000972 "Palmoplantar hyperkeratosis" [Orphanet:23100]
Orphanet:23100 "Palmoplantar hyperkeratosis/keratoderma" [Orphanet:23100]
OMIM: "Hyperkeratosis, diffuse palmoplantar (tylosis)" [OMIM:Hyperkeratosis, diffuse palmoplantar (tylosis)]
OMIM: "Keratosis palmaris" [OMIM:Keratosis palmaris]
OMIM: "Keratosis plantaris" [OMIM:Keratosis plantaris]
OMIM: "Palmoplantar keratoderma (in some patients)" [OMIM:Palmoplantar keratoderma (in some patients)]
UMLS:C0022596 "Palmoplantar Keratosis" [Orphanet:23100]
Is a (Direct Parents):
MedDRA Hyperkeratoses
HPO         Palmoplantar hyperkeratosis
Orphanet Abnormality of the skin
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal appendicular skeleton morphology(HPO:0011844)
                Abnormality of limb bone morphology(HPO:0002813)
                   Abnormality of the upper limb(HPO:0002817)
                      Abnormality of the hand(HPO:0001155)
                         Abnormality of the palm(HPO:0100871)
                            Palmoplantar hyperkeratosis(HPO:0000972)
                               Diffuse palmoplantar hyperkeratosis(HPO:0007447)
       Abnormality of the integument(HPO:0001574)
          Abnormality of the skin(HPO:0000951)
             Regional abnormality of skin(HPO:0011356)
                Abnormality of the plantar skin of foot(HPO:0100872)
                   Palmoplantar hyperkeratosis(HPO:0000972)
                      Diffuse palmoplantar hyperkeratosis(HPO:0007447)
             Generalized abnormality of skin(HPO:0011354)
                Abnormality of skin morphology(HPO:0011121)
                   Thickened skin(HPO:0001072)
                      Epidermal thickening(HPO:0011368)
                         Hyperkeratosis(HPO:0000962)
                            Palmar hyperkeratosis(HPO:0010765)
                               Palmoplantar hyperkeratosis(HPO:0000972)
                                  Diffuse palmoplantar hyperkeratosis(HPO:0007447)
                            Plantar hyperkeratosis(HPO:0007556)
                               Palmoplantar hyperkeratosis(HPO:0000972)
                                  Diffuse palmoplantar hyperkeratosis(HPO:0007447)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Cornification and dystrophic skin disorders(MedDRA:10011063)
       Hyperkeratoses(MedDRA:10020648)
          Diffuse palmoplantar hyperkeratosis(HPO:0007447)
Database Frequency: 8 / 7739
Resource:

All diseases associated with this symptom:

Arrhythmogenic right ventricular dysplasia, familial, 11 (OMIM:610476)
Buschke-Ollendorff syndrome (Orphanet:1306)
Epidermolytic palmoplantar keratoderma (Orphanet:2199)
Familial isolated dilated cardiomyopathy (Orphanet:154)
ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 5 (OMIM:604777)
Keratosis palmaris et plantaris - clinodactyly (Orphanet:86919)
Palmoplantar keratoderma-esophageal carcinoma syndrome (Orphanet:2198)
Tyrosinemia type 2 (Orphanet:28378)