Blindness

Symptom Information:

Symptom ID: HPO:0000618
Synonyms:
Visual loss [Orphanet:5450]
Dim vision (disorder) [Orphanet:5450]
Visual impairment (disorder) [Orphanet:5450]
Amaurosis [HPO:0000618]
Visual impairment [Orphanet:5450]
Blind Vision [Orphanet:5450]
Blindness [OMIM:Blindness]
Visual loss/blindness/amblyopia [Orphanet:5450]
Blindness [Orphanet:5450]
Visual impairment [MedDRA:10047571]
Abnormal retinal correspondence [MedDRA:10047571]
Abnormal vision [MedDRA:10047571]
Abnormal vision NOS [MedDRA:10047571]
After images [MedDRA:10047571]
Aphose [MedDRA:10047571]
Binocular vision disorder, unspecified [MedDRA:10047571]
Disorder sight [MedDRA:10047571]
Fusion with defective stereopsis [MedDRA:10047571]
Increasing visual impairment [MedDRA:10047571]
Near vision disturbance [MedDRA:10047571]
Other disorders of binocular vision [MedDRA:10047571]
Other specified visual disturbances [MedDRA:10047571]
Other visual distortions and entoptic phenomena [MedDRA:10047571]
Psychophysical visual disturbances [MedDRA:10047571]
Simultaneous visual perception without fusion [MedDRA:10047571]
Spots before eyes [MedDRA:10047571]
Subjective visual disturbance, unspecified [MedDRA:10047571]
Subjective visual disturbances [MedDRA:10047571]
Suppression of binocular vision [MedDRA:10047571]
Unspecified visual disturbance [MedDRA:10047571]
Vision abnormal [MedDRA:10047571]
Vision abnormal aggravated [MedDRA:10047571]
Vision abnormal NOS [MedDRA:10047571]
Vision abnormal NOS exacerbated [MedDRA:10047571]
Vision dim [MedDRA:10047571]
Visual distortions of shape and size [MedDRA:10047571]
Visual disturbance [MedDRA:10047571]
Visual disturbance NOS [MedDRA:10047571]
Visual disturbances [MedDRA:10047571]
Visual disturbances subjective [MedDRA:10047571]
Visual phenomena [MedDRA:10047571]
Bilateral abnormal vision [MedDRA:10047571]
Unilateral abnormal vision [MedDRA:10047571]
Dysopia [MedDRA:10047571]
Visual impairment transient [MedDRA:10047571]
Blindness [MedDRA:10005169]
Better eye: moderate vision impairment
lesser eye: blind, not further specified [MedDRA:10005169]
Better eye: moderate vision impairment
lesser eye: impairment not further specified [MedDRA:10005169]
Better eye: moderate vision impairment
lesser eye: near-total vision impairment [MedDRA:10005169]
Better eye: moderate vision impairment
lesser eye: profound vision impairment [MedDRA:10005169]
Better eye: moderate vision impairment
lesser eye: severe vision impairment [MedDRA:10005169]
Better eye: moderate vision impairment
lesser eye: total vision impairment [MedDRA:10005169]
Better eye: moderate vision impairment
unqualified visual loss, both eyes [MedDRA:10005169]
Better eye: near-total vision impairment
lesser eye: near-total vision impairment [MedDRA:10005169]
Better eye: near-total vision impairment
lesser eye: not further specified [MedDRA:10005169]
Better eye: near-total vision impairment
lesser eye: total vision impairment [MedDRA:10005169]
Better eye: profound vision impairment
lesser eye: near-total vision impairment [MedDRA:10005169]
Better eye: profound vision impairment
lesser eye: not further specified [MedDRA:10005169]
Better eye: profound vision impairment
lesser eye: profound vision impairment [MedDRA:10005169]
Better eye: profound vision impairment
lesser eye: total vision impairment [MedDRA:10005169]
Better eye: severe vision impairment
lesser eye: blind, not further specified [MedDRA:10005169]
Better eye: severe vision impairment
lesser eye: near-total vision impairment [MedDRA:10005169]
Better eye: severe vision impairment
lesser eye: profound vision impairment [MedDRA:10005169]
Better eye: severe vision impairment
lesser eye: severe vision impairment [MedDRA:10005169]
Better eye: severe vision impairment
lesser eye: total vision impairment [MedDRA:10005169]
Better eye: severe vision impairment
lesser eye
impairment not further specified [MedDRA:10005169]
Better eye: total vision impairment
lesser eye: total vision impairment [MedDRA:10005169]
Better eye:moderate vision impairment
lesser eye:moderate vision impairment [MedDRA:10005169]
Bilateral blindness [MedDRA:10005169]
Blind [MedDRA:10005169]
Blind both eyes [MedDRA:10005169]
Blind hypertensive eye [MedDRA:10005169]
Blind hypotensive eye [MedDRA:10005169]
Blindness and low vision [MedDRA:10005169]
Blindness NOS [MedDRA:10005169]
Blindness of both eyes, impairment level not further specified [MedDRA:10005169]
Blindness, both eyes [MedDRA:10005169]
Blindness, one eye, low vision other eye [MedDRA:10005169]
Blindness, one eye
low vision other eye [MedDRA:10005169]
Impairment level not further specified [MedDRA:10005169]
Legal blindness, as defined in U.S.A. [MedDRA:10005169]
Loss of vision [MedDRA:10005169]
Moderate or severe vision impairment, better eye
profound vision impairment of lesser eye [MedDRA:10005169]
Moderate or severe vision impairment, both eyes [MedDRA:10005169]
Moderate or severe vision impairment, both eyes, impairment level not further specified [MedDRA:10005169]
One eye: near-total vision impairment
other eye: near-normal vision [MedDRA:10005169]
One eye: near-total vision impairment
other eye: normal vision [MedDRA:10005169]
One eye: near-total vision impairment
other eye: vision not specified [MedDRA:10005169]
One eye: profound vision impairment
other eye: near-normal vision [MedDRA:10005169]
One eye: profound vision impairment
other eye: normal vision [MedDRA:10005169]
One eye: profound vision impairment
other eye: vision not specified [MedDRA:10005169]
One eye: severe vision impairment
other eye: near-normal vision [MedDRA:10005169]
One eye: severe vision impairment
other eye: normal vision [MedDRA:10005169]
One eye: severe vision impairment
other eye: vision not specified [MedDRA:10005169]
One eye: total vision impairment
other eye: near-normal vision [MedDRA:10005169]
One eye: total vision impairment
other eye: normal vision [MedDRA:10005169]
One eye: total vision impairment
other eye: not specified [MedDRA:10005169]
Profound vision impairment, both eyes [MedDRA:10005169]
Unqualified visual loss, both eyes [MedDRA:10005169]
Unspecified visual loss [MedDRA:10005169]
Vision impairment of lesser eye [MedDRA:10005169]
Vision loss [MedDRA:10005169]
Blindness impairment level not further specified [MedDRA:10005169]
No light perception [MedDRA:10005169]
Amaurosis [OMIM:Amaurosis]
Blindness (6 to 14 years) [OMIM:Blindness (6 to 14 years)]
Blindness (WWS) [OMIM:Blindness (WWS)]
Blindness (in some patients) [OMIM:Blindness (in some patients)]
Blindness (onset in fourth or fifth decade) [OMIM:Blindness (onset in fourth or fifth decade)]
Blindness (onset in infancy) [OMIM:Blindness (onset in infancy)]
Blindness (rare) [OMIM:Blindness (rare)]
Loss of vision (34%) [OMIM:Loss of vision (34%)]
Loss of vision (rare) [OMIM:Loss of vision (rare)]
Vision loss [OMIM:Vision loss]
Vision loss (chronic phase) [OMIM:Vision loss (chronic phase)]
Visual disturbances [OMIM:Visual disturbances]
Visual impairment (50-70% of patients) [OMIM:Visual impairment (50-70% of patients)]
Visual impairment (55%) [OMIM:Visual impairment (55%)]
Visual impairment (childhood-onset) [OMIM:Visual impairment (childhood-onset)]
Visual impairment (rare) [OMIM:Visual impairment (rare)]
Visual loss (in 1 family) [OMIM:Visual loss (in 1 family)]
Visual loss (in some patients) [OMIM:Visual loss (in some patients)]
Blindness (excl colour blindness) [MedDRA:10005170]
Amaurosis [MedDRA:10001902]
Quality:
Cross references:
HPO:0000572 "Visual loss" [Orphanet:5450]
Orphanet:5450 "Visual loss/blindness/amblyopia" [Orphanet:5450]
OMIM: "Blindness" [OMIM:Blindness]
OMIM: "Amaurosis" [OMIM:Amaurosis]
OMIM: "Blindness (6 to 14 years)" [OMIM:Blindness (6 to 14 years)]
OMIM: "Blindness (WWS)" [OMIM:Blindness (WWS)]
OMIM: "Blindness (in some patients)" [OMIM:Blindness (in some patients)]
OMIM: "Blindness (onset in fourth or fifth decade)" [OMIM:Blindness (onset in fourth or fifth decade)]
OMIM: "Blindness (onset in infancy)" [OMIM:Blindness (onset in infancy)]
OMIM: "Blindness (rare)" [OMIM:Blindness (rare)]
OMIM: "Loss of vision (34%)" [OMIM:Loss of vision (34%)]
OMIM: "Loss of vision (rare)" [OMIM:Loss of vision (rare)]
OMIM: "Vision loss" [OMIM:Vision loss]
OMIM: "Vision loss (chronic phase)" [OMIM:Vision loss (chronic phase)]
OMIM: "Visual disturbances" [OMIM:Visual disturbances]
OMIM: "Visual impairment (50-70% of patients)" [OMIM:Visual impairment (50-70% of patients)]
OMIM: "Visual impairment (55%)" [OMIM:Visual impairment (55%)]
OMIM: "Visual impairment (childhood-onset)" [OMIM:Visual impairment (childhood-onset)]
OMIM: "Visual impairment (rare)" [OMIM:Visual impairment (rare)]
OMIM: "Visual loss (in 1 family)" [OMIM:Visual loss (in 1 family)]
OMIM: "Visual loss (in some patients)" [OMIM:Visual loss (in some patients)]
UMLS:C0376288 "Amaurosis" [HPO:0000618]
UMLS:C0456909 "Blindness" [HPO:0000618]
UMLS:C0042798 "Visual impairment" [Orphanet:5450]
UMLS:C0456909 "Blind Vision" [Orphanet:5450]
Is a (Direct Parents):
MedDRA Visual loss
Orphanet Abnormality of the eye
MedDRA Visual disorders NEC
MedDRA Vision disorders
Orphanet Visual loss
HPO         Visual impairment
MedDRA Neurologic visual problems NEC
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the eye(HPO:0000478)
          Abnormal eye physiology(HPO:0012373)
             Abnormality of vision(HPO:0000504)
                Visual impairment(HPO:0000505)
                   Blindness(HPO:0000618)
MedDRA:
Eye disorders(MedDRA:10015919)
    Vision disorders(MedDRA:10047518)
       Visual disorders NEC(MedDRA:10047541)
          Visual loss(HPO:0000572)
             Blindness(HPO:0000618)
          Blindness(HPO:0000618)
       Visual loss(HPO:0000572)
             Blindness(HPO:0000618)
       Blindness(HPO:0000618)
Nervous system disorders(MedDRA:10029205)
    Neurological disorders of the eye(MedDRA:10029301)
       Neurologic visual problems NEC(MedDRA:10029292)
          Blindness(HPO:0000618)
          Visual loss(HPO:0000572)
             Blindness(HPO:0000618)
Database Frequency: 124 / 7739
Resource:

All diseases associated with this symptom:

ACHROMATOPSIA 3 (OMIM:262300)
AMYLOIDOSIS OF GINGIVA AND CONJUNCTIVA, WITH MENTAL RETARDATION (OMIM:204850)
ARIMA SYNDROME (OMIM:243910)
AXENFELD-RIEGER SYNDROME, TYPE 2 (OMIM:601499)
Achromatopsia (Orphanet:49382)
Alpers syndrome (Orphanet:726)
Alström syndrome (Orphanet:64)
Autosomal dominant neovascular inflammatory vitreoretinopathy (Orphanet:329211)
Autosomal dominant optic atrophy plus syndrome (Orphanet:1215)
Autosomal recessive cerebellar ataxia - blindness - deafness (Orphanet:95433)
Autosomal recessive deafness-onychodystrophy syndrome (Orphanet:79500)
Autosomal recessive malignant osteopetrosis (Orphanet:667)
BRITTLE CORNEA SYNDROME 1 (OMIM:229200)
BROWN-VIALETTO-VAN LAERE SYNDROME 2 (OMIM:614707)
Bardet-Biedl syndrome 17 (OMIM:615994)
Bifunctional enzyme deficiency (Orphanet:300)
Biotinidase deficiency (Orphanet:79241)
Buschke-Ollendorff syndrome (Orphanet:1306)
CACH syndrome (Orphanet:135)
CADASIL (Orphanet:136)
CATARACT, CONGENITAL, WITH MENTAL IMPAIRMENT AND DENTATE GYRUS ATROPHY (OMIM:607674)
CEREBELLAR ATAXIA, AREFLEXIA, PES CAVUS, OPTIC ATROPHY, AND SENSORINEURALHEARING LOSS (OMIM:601338)
CEREBRAL SCLEROSIS, DIFFUSE, SCHOLZ TYPE (OMIM:302700)
CLN1 disease (Orphanet:228329)
CLN3 disease (Orphanet:228346)
CLN7 disease (Orphanet:228366)
COENZYME Q10 DEFICIENCY, PRIMARY, 1 (OMIM:607426)
Canavan disease (Orphanet:141)
Cerebroretinal vasculopathy (Orphanet:3421)
Coats plus syndrome (Orphanet:313838)
Combined oxidative phosphorylation defect type 14 (Orphanet:319519)
Cone rod dystrophy (Orphanet:1872)
Cushing disease (Orphanet:96253)
Dermatoosteolysis, Kirghizian type (Orphanet:1657)
Diabetic embryopathy (Orphanet:1926)
Dysosteosclerosis (Orphanet:1782)
EXUDATIVE VITREORETINOPATHY 4 (OMIM:601813)
Ectodermal dysplasia - blindness (Orphanet:1806)
Ehlers-Danlos syndrome, kyphoscoliotic type (Orphanet:1900)
Familial exudative vitreoretinopathy (Orphanet:891)
Fibrous dysplasia of bone (Orphanet:249)
Fraser syndrome (Orphanet:2052)
GM2-gangliosidosis, AB variant (Orphanet:309246)
Giant cell arteritis (Orphanet:397)
Glaucoma - ectopia - microspherophakia - stiff joints - short stature (Orphanet:2084)
Glycogen storage disease due to phosphoglycerate kinase 1 deficiency (Orphanet:713)
Gyrate atrophy of choroid and retina (Orphanet:414)
HERNS syndrome (Orphanet:63261)
Hereditary mucoepithelial dysplasia (Orphanet:1839)
Hereditary vascular retinopathy (Orphanet:71291)
Hypoplasminogenemia (Orphanet:722)
Hypotrichosis with juvenile macular degeneration (Orphanet:1573)
Insulin-resistance syndrome type A (Orphanet:2297)
Isolated NADH-CoQ reductase deficiency (Orphanet:2609)
Joubert syndrome 6 (OMIM:610688)
Joubert syndrome with oculorenal defect (Orphanet:2318)
KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME, AUTOSOMAL DOMINANT (OMIM:148210)
KID syndrome (Orphanet:477)
KRABBE DISEASE (OMIM:245200)
Krabbe disease (Orphanet:487)
LCAT deficiency (Orphanet:650)
Leber congenital amaurosis 1 (OMIM:204000)
Leber congenital amaurosis 10 (OMIM:611755)
Leber congenital amaurosis 11 (OMIM:613837)
Leber congenital amaurosis 2 (OMIM:204100)
Leber hereditary optic neuropathy (Orphanet:104)
Leber plus disease (Orphanet:99718)
Leigh syndrome (Orphanet:506)
Ligneous conjunctivitis (Orphanet:97231)
MENTAL RETARDATION, KERATOCONUS, FEBRILE SEIZURES, AND SINOATRIALBLOCK (OMIM:609438)
MICROPHTHALMIA, SYNDROMIC 1 (OMIM:309800)
MIGRAINE, FAMILIAL HEMIPLEGIC, 3 (OMIM:609634)
MOMO syndrome (Orphanet:2563)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 1 (OMIM:236670)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 11 (OMIM:615181)
MUSK, INABILITY TO SMELL (OMIM:254150)
Maternally-inherited diabetes and deafness (Orphanet:225)
McCune-Albright syndrome (Orphanet:562)
Megalencephaly - polymicrogyria - postaxial polydactyly - hydrocephalus (Orphanet:83473)
Methylcobalamin deficiency type cblE (Orphanet:2169)
Methylcobalamin deficiency type cblG (Orphanet:2170)
Microphthalmia with brain and digit anomalies (Orphanet:139471)
Muscle-eye-brain disease (Orphanet:588)
NARP syndrome (Orphanet:644)
Necrotizing encephalomyelopathy, subacute, of Leigh, adult (OMIM:161700)
Nephronophthisis 15 (OMIM:614845)
Norrie disease (Orphanet:649)
OPTIC ATROPHY, HEARING LOSS, AND PERIPHERAL NEUROPATHY, AUTOSOMALRECESSIVE (OMIM:258650)
OPTICOACOUSTIC NERVE ATROPHY WITH DEMENTIA (OMIM:311150)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 1 (OMIM:259700)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 2 (OMIM:259710)
Oculofaciocardiodental syndrome (Orphanet:2712)
Ophthalmomandibulomelic dysplasia (Orphanet:2741)
Osteoporosis - pseudoglioma (Orphanet:2788)
PALLIDAL DEGENERATION, PROGRESSIVE, WITH RETINITIS PIGMENTOSA (OMIM:260200)
POLYCYSTIC KIDNEY, CATARACT, AND CONGENITAL BLINDNESS (OMIM:263100)
Papillary fibroelastoma of the heart (Orphanet:208600)
Pierson syndrome (Orphanet:2670)
Polyostotic fibrous dysplasia (Orphanet:93276)
Posterior column ataxia - retinitis pigmentosa (Orphanet:88628)
Progressive myoclonic epilepsy type 3 (Orphanet:263516)
Proximal tubulopathy - diabetes mellitus - cerebellar ataxia (Orphanet:3390)
RETINITIS PIGMENTOSA 35 (OMIM:610282)
RETINOPATHY, PERICENTRAL PIGMENTARY, DOMINANT (OMIM:180210)
Renpenning syndrome (Orphanet:3242)
Retinitis pigmentosa 10 (OMIM:180105)
Retinopathy of prematurity (Orphanet:90050)
SCLEROSTEOSIS 1 (OMIM:269500)
STICKLER SYNDROME, TYPE I (OMIM:108300)
Sandhoff disease, infantile form (Orphanet:309155)
Senior-Loken syndrome 5 (OMIM:609254)
Severe X-linked intellectual deficit, Gustavson type (Orphanet:3078)
Stickler syndrome (Orphanet:828)
THROMBOPHILIA DUE TO PROTEIN S DEFICIENCY, AUTOSOMAL RECESSIVE (OMIM:614514)
Tay-Sachs disease (Orphanet:845)
Thiamine-responsive megaloblastic anemia syndrome (Orphanet:49827)
Tyrosinemia type 2 (Orphanet:28378)
WEILL-MARCHESANI SYNDROME 1 (OMIM:277600)
Weill-Marchesani syndrome (Orphanet:3449)
Wolfram syndrome, mitochondrial form (OMIM:598500)
X-linked cerebral adrenoleukodystrophy (Orphanet:139396)
XYLOSIDASE DEFICIENCY (OMIM:278900)
[DEL] LEBER OPTIC ATROPHY (OMIM:535000)
[DEL] PSEUDOXANTHOMA ELASTICUM (OMIM:264800)