Proximal muscle weakness

Symptom Information:

Symptom ID: HPO:0003701
Synonyms:
Muscle weakness, proximal [HPO:0003701]
Proximal limb muscle weakness [HPO:0003701]
Proximal limb weakness [HPO:0003701]
Proximal neurogenic muscle weakness [HPO:0003701]
Muscle weakness, proximal [OMIM:Muscle weakness, proximal]
Proximal limb muscle weakness [OMIM:Proximal limb muscle weakness]
Proximal limb weakness [OMIM:Proximal limb weakness]
Proximal muscle weakness [OMIM:Proximal muscle weakness]
Proximal neurogenic muscle weakness [OMIM:Proximal neurogenic muscle weakness]
Proximal limb muscle weakness (occurs later) [OMIM:Proximal limb muscle weakness (occurs later)]
Proximal limb muscle weakness. [OMIM:Proximal limb muscle weakness.]
Proximal muscle weakness (120270.0002) [OMIM:Proximal muscle weakness (120270.0002)]
Proximal muscle weakness (85% of patients) [OMIM:Proximal muscle weakness (85% of patients)]
Proximal muscle weakness (occasional) [OMIM:Proximal muscle weakness (occasional)]
Quality:
Cross references:
OMIM: "Muscle weakness, proximal" [OMIM:Muscle weakness, proximal]
OMIM: "Proximal limb muscle weakness" [OMIM:Proximal limb muscle weakness]
OMIM: "Proximal limb weakness" [OMIM:Proximal limb weakness]
OMIM: "Proximal muscle weakness" [OMIM:Proximal muscle weakness]
OMIM: "Proximal neurogenic muscle weakness" [OMIM:Proximal neurogenic muscle weakness]
OMIM: "Proximal limb muscle weakness (occurs later)" [OMIM:Proximal limb muscle weakness (occurs later)]
OMIM: "Proximal limb muscle weakness." [OMIM:Proximal limb muscle weakness.]
OMIM: "Proximal muscle weakness (120270.0002)" [OMIM:Proximal muscle weakness (120270.0002)]
OMIM: "Proximal muscle weakness (85% of patients)" [OMIM:Proximal muscle weakness (85% of patients)]
OMIM: "Proximal muscle weakness (occasional)" [OMIM:Proximal muscle weakness (occasional)]
Is a (Direct Parents):
HPO         Muscle weakness
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle physiology(HPO:0011804)
             Muscle weakness(HPO:0001324)
                Proximal muscle weakness(HPO:0003701)
MedDRA:
Database Frequency: 105 / 7739
Resource:

All diseases associated with this symptom:

AMYOTROPHIC LATERAL SCLEROSIS 8 (OMIM:608627)
AXIAL OSTEOMALACIA (OMIM:109130)
Adult-onset multiple mitochondrial DNA deletion syndrome due to DGUOK deficiency (Orphanet:329314)
Adult-onset proximal spinal muscular atrophy, autosomal dominant (Orphanet:209335)
Autosomal dominant Charcot-Marie-Tooth disease type 2K (Orphanet:99944)
Autosomal dominant centronuclear myopathy (Orphanet:169189)
Autosomal dominant limb-girdle muscular dystrophy type 1B (Orphanet:264)
Autosomal dominant limb-girdle muscular dystrophy type 1C (Orphanet:265)
Autosomal dominant optic atrophy, classic type (Orphanet:98673)
Autosomal dominant spastic paraplegia type 9 (Orphanet:100990)
Autosomal recessive Emery-Dreifuss muscular dystrophy (Orphanet:98855)
Autosomal recessive ataxia due to ubiquinone deficiency (Orphanet:139485)
Autosomal recessive limb-girdle muscular dystrophy type 2B (Orphanet:268)
Autosomal recessive limb-girdle muscular dystrophy type 2C (Orphanet:353)
Autosomal recessive limb-girdle muscular dystrophy type 2D (Orphanet:62)
Autosomal recessive limb-girdle muscular dystrophy type 2E (Orphanet:119)
Autosomal recessive limb-girdle muscular dystrophy type 2F (Orphanet:219)
Autosomal recessive limb-girdle muscular dystrophy type 2I (Orphanet:34515)
Autosomal recessive limb-girdle muscular dystrophy type 2J (Orphanet:140922)
Autosomal recessive limb-girdle muscular dystrophy type 2L (Orphanet:206549)
Autosomal recessive limb-girdle muscular dystrophy type 2M (Orphanet:206554)
Autosomal recessive limb-girdle muscular dystrophy type 2N (Orphanet:206559)
Autosomal recessive limb-girdle muscular dystrophy type 2O (Orphanet:206564)
Autosomal recessive limb-girdle muscular dystrophy type 2Q (Orphanet:254361)
Autosomal recessive limb-girdle muscular dystrophy type 2S (Orphanet:369840)
Autosomal recessive limb-girdle muscular dystrophy type 2T (Orphanet:363623)
Autosomal recessive lower motor neuron disease with childhood onset (Orphanet:206580)
Autosomal recessive progressive external ophthalmoplegia (Orphanet:254886)
Bethlem myopathy (Orphanet:610)
Cap myopathy (Orphanet:171881)
Cardiomyopathy, dilated, 1X (OMIM:611615)
Charcot-Marie-Tooth disease type 4B1 (Orphanet:99955)
Congenital fiber-type disproportion myopathy (Orphanet:2020)
Congenital multicore myopathy with external ophthalmoplegia (Orphanet:98905)
Congenital muscular dystrophy with cerebellar involvement (Orphanet:370959)
Congenital muscular dystrophy, Ullrich type (Orphanet:75840)
Congenital myasthenic syndromes (Orphanet:590)
Desminopathy (Orphanet:98909)
Diaphyseal medullary stenosis - bone malignancy (Orphanet:85182)
Distal myopathy, Nonaka type (Orphanet:602)
EMERY-DREIFUSS MUSCULAR DYSTROPHY 4, AUTOSOMAL DOMINANT (OMIM:612998)
EMERY-DREIFUSS MUSCULAR DYSTROPHY 5, AUTOSOMAL DOMINANT (OMIM:612999)
EMERY-DREIFUSS MUSCULAR DYSTROPHY 7, AUTOSOMAL DOMINANT (OMIM:614302)
EPIPHYSEAL DYSPLASIA, MULTIPLE, 3 (OMIM:600969)
Ehlers-Danlos syndrome due to tenascin-X deficiency (Orphanet:230839)
FRONTOTEMPORAL DEMENTIA AND/OR AMYOTROPHIC LATERAL SCLEROSIS 2 (OMIM:615911)
Focal myositis (Orphanet:48918)
Generalized congenital lipodystrophy with myopathy (Orphanet:228429)
Giant axonal neuropathy (Orphanet:643)
Glycogen storage disease due to LAMP-2 deficiency (Orphanet:34587)
Glycogen storage disease due to acid maltase deficiency (Orphanet:365)
Gyrate atrophy of choroid and retina (Orphanet:414)
Hereditary inclusion body myopathy - joint contractures - ophthalmoplegia (Orphanet:79091)
Hereditary motor and sensory neuropathy type 6 (Orphanet:90120)
Hereditary motor and sensory neuropathy, Okinawa type (Orphanet:90117)
Hereditary myoclonus - progressive distal muscular atrophy (Orphanet:2590)
Hereditary proximal myopathy with early respiratory failure (Orphanet:178464)
INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE WITH OR WITHOUTFRONTOTEMPORAL DEMENTIA 1 (OMIM:167320)
INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE WITH OR WITHOUTFRONTOTEMPORAL DEMENTIA 3 (OMIM:615424)
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia (Orphanet:52430)
Inclusion body myositis (Orphanet:611)
Laing distal myopathy (Orphanet:59135)
MUSCULAR DYSTROPHY, CONGENITAL, MEROSIN-POSITIVE (OMIM:609456)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 2 (OMIM:613156)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 6 (OMIM:608840)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH OR WITHOUTMENTAL RETARDATION), TYPE B, 5 (OMIM:606612)
MYASTHENIA GRAVIS (OMIM:254200)
MYASTHENIC SYNDROME, CONGENITAL, 13 (OMIM:614750)
MYASTHENIC SYNDROME, CONGENITAL, 7, PRESYNAPTIC (OMIM:616040)
MYOPATHY WITH ABNORMAL LIPID METABOLISM (OMIM:255100)
MYOPATHY WITH EXTRAPYRAMIDAL SIGNS (OMIM:615673)
MYOPATHY WITH GIANT ABNORMAL MITOCHONDRIA (OMIM:255140)
MYOPATHY, CONGENITAL, WITH FIBER-TYPE DISPROPORTION (OMIM:255310)
MYOPATHY, REDUCING BODY, X-LINKED, CHILDHOOD-ONSET (OMIM:300718)
Mitochondrial DNA depletion syndrome, myopathic form (Orphanet:254875)
Muscle filaminopathy (Orphanet:171445)
Myopathy and diabetes mellitus (Orphanet:2596)
Myosclerosis (Orphanet:289380)
Myotilin-related myofibrillar myopathy without spheroid body (Orphanet:98911)
NARP syndrome (Orphanet:644)
NEMALINE MYOPATHY 1 (OMIM:609284)
NEMALINE MYOPATHY 2 (OMIM:256030)
Nemaline myopathy (Orphanet:607)
Neutral lipid storage myopathy (Orphanet:98908)
Oculopharyngeal muscular dystrophy (Orphanet:270)
Oculopharyngodistal myopathy (Orphanet:98897)
PIGMENTED NODULAR ADRENOCORTICAL DISEASE, PRIMARY, 4 (OMIM:615830)
PLEOCONIAL MYOPATHY WITH SALT CRAVING (OMIM:262900)
POLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY (OMIM:615895)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 3 (OMIM:609286)
PROXIMAL MYOPATHY WITH FOCAL DEPLETION OF MITOCHONDRIA (OMIM:600706)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Polyglucosan body myopathy type 1 (ORPHA:397937)
Proximal myotonic myopathy (Orphanet:606)
Proximal spinal muscular atrophy type 4 (Orphanet:83420)
Reducing body myopathy (Orphanet:97239)
Riboflavin transporter deficiency (Orphanet:97229)
SPASTIC PARAPLEGIA 73, AUTOSOMAL DOMINANT (OMIM:616282)
Spheroid body myopathy (Orphanet:268129)
Spinocerebellar ataxia with epilepsy (Orphanet:254881)
Steinert myotonic dystrophy (Orphanet:273)
Stormorken-Sjaastad-Langslet syndrome (Orphanet:3204)
Tubular aggregate myopathy (Orphanet:2593)
VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 5, WITH ORWITHOUT MUSCLE WEAKNESS (OMIM:615441)
X-linked myopathy with postural muscle atrophy (Orphanet:178461)