IgM deficiency

Symptom Information:

Symptom ID: HPO:0002850
Synonyms:
Decreased IgM [HPO:0002850]
Decreased IgM level [HPO:0002850]
Reduced IgM levels [HPO:0002850]
Decreased IgM [OMIM:Decreased IgM]
IgM deficiency [OMIM:IgM deficiency]
Reduced IgM levels [OMIM:Reduced IgM levels]
Quality:
Cross references:
OMIM: "Decreased IgM" [OMIM:Decreased IgM]
OMIM: "IgM deficiency" [OMIM:IgM deficiency]
OMIM: "Reduced IgM levels" [OMIM:Reduced IgM levels]
Is a (Direct Parents):
HPO         Decreased antibody level in blood
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of immune system physiology(HPO:0010978)
             Abnormality of humoral immunity(HPO:0005368)
                Abnormal immunoglobulin level(HPO:0010701)
                   Decreased antibody level in blood(HPO:0004313)
                      IgM deficiency(HPO:0002850)
          Abnormality of cellular immune system(HPO:0010987)
             Abnormality of leukocytes(HPO:0001881)
                Abnormality of lymphocytes(HPO:0004332)
                   Abnormality of B cells(HPO:0002846)
                      Abnormality of B cell physiology(HPO:0005372)
                         Abnormal immunoglobulin level(HPO:0010701)
                            Decreased antibody level in blood(HPO:0004313)
                               IgM deficiency(HPO:0002850)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of leukocytes(HPO:0001881)
             Abnormality of lymphocytes(HPO:0004332)
                Abnormality of B cells(HPO:0002846)
                   Abnormality of B cell physiology(HPO:0005372)
                      Abnormal immunoglobulin level(HPO:0010701)
                         Decreased antibody level in blood(HPO:0004313)
                            IgM deficiency(HPO:0002850)
MedDRA:
Database Frequency: 18 / 7739
Resource:

All diseases associated with this symptom:

Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation (Orphanet:324530)
Bloom syndrome (Orphanet:125)
IMMUNE DEFICIENCY DISEASE (OMIM:242850)
IMMUNODEFICIENCY, COMMON VARIABLE, 1 (OMIM:607594)
IMMUNODEFICIENCY, COMMON VARIABLE, 2 (OMIM:240500)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
LYMPHOID SYSTEM DETERIORATION, PROGRESSIVE (OMIM:247630)
Lung fibrosis - immunodeficiency - 46,XX gonadal dysgenesis (Orphanet:137631)
MENTAL RETARDATION, X-LINKED, SYNDROMIC, CHUDLEY-SCHWARTZ TYPE (OMIM:300861)
Microcephalic primordial dwarfism, Toriello type (Orphanet:2643)
Persistent polyclonal B-cell lymphocytosis (Orphanet:300324)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Primary immunodeficiency syndrome due to p14 deficiency (Orphanet:90023)
Proximal myotonic myopathy (Orphanet:606)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Transcobalamin deficiency (Orphanet:859)
WISKOTT-ALDRICH SYNDROME (OMIM:301000)
WISKOTT-ALDRICH SYNDROME, AUTOSOMAL DOMINANT FORM (OMIM:600903)