Gastroesophageal reflux

Symptom Information:

Symptom ID: HPO:0002020
Synonyms:
Acid reflux disease [HPO:0002020]
Gastroesophageal reflux disease [HPO:0002020]
Gastroesophageal reflux disease (disorder) [Orphanet:27240]
Gastroesophageal reflux disease [Orphanet:27240]
Gastroesophageal reflux [OMIM:Gastroesophageal reflux]
Gastroesophageal reflux disease [OMIM:Gastroesophageal reflux disease]
Gastroesophageal reflux/pyrosis/esophagitis/hiatal hernia/gastroparesia [Orphanet:27240]
Gastrooesophageal reflux disease [Orphanet:27240]
Gastrooesophageal reflux disease [MedDRA:10017885]
Acid reflux (oesophageal) [MedDRA:10017885]
Bile reflux (oesophageal) [MedDRA:10017885]
Esophageal reflux [MedDRA:10017885]
Gastrooesophageal reflux [MedDRA:10017885]
Gastroesophageal reflux [MedDRA:10017885]
GERD [MedDRA:10017885]
Oesophageal reflux [MedDRA:10017885]
Oesophageal reflux aggravated [MedDRA:10017885]
Reflux esophagitis [MedDRA:10017885]
Reflux oesophagitis [MedDRA:10017885]
Bile reflux (esophageal) [MedDRA:10017885]
Esophageal reflux aggravated [MedDRA:10017885]
Esophageal acid reflux [MedDRA:10017885]
Acid reflux (esophageal) [MedDRA:10017885]
Oesophageal acid reflux [MedDRA:10017885]
Gastroesophageal reflux disease [MedDRA:10017885]
Non-erosive reflux disease [MedDRA:10017885]
Esophageal reflux (in some patients) [OMIM:Esophageal reflux (in some patients)]
Gastroesophageal reflux (1 patient) [OMIM:Gastroesophageal reflux (1 patient)]
Gastroesophageal reflux (in some patients) [OMIM:Gastroesophageal reflux (in some patients)]
Gastroesophageal reflux (infancy) [OMIM:Gastroesophageal reflux (infancy)]
Gastroesophageal reflux (less common) [OMIM:Gastroesophageal reflux (less common)]
Gastroesophageal reflux (rare) [OMIM:Gastroesophageal reflux (rare)]
Gastroesophageal reflux (uncommon) [OMIM:Gastroesophageal reflux (uncommon)]
Pyrosis [MedDRA:10037676]
Heartburn (finding) [Orphanet:27240]
Heartburn [Orphanet:27240]
Quality:
Cross references:
Orphanet:27240 "Gastroesophageal reflux/pyrosis/esophagitis/hiatal hernia/gastroparesia" [Orphanet:27240]
OMIM: "Gastroesophageal reflux" [OMIM:Gastroesophageal reflux]
OMIM: "Gastroesophageal reflux disease" [OMIM:Gastroesophageal reflux disease]
OMIM: "Esophageal reflux (in some patients)" [OMIM:Esophageal reflux (in some patients)]
OMIM: "Gastroesophageal reflux (1 patient)" [OMIM:Gastroesophageal reflux (1 patient)]
OMIM: "Gastroesophageal reflux (in some patients)" [OMIM:Gastroesophageal reflux (in some patients)]
OMIM: "Gastroesophageal reflux (infancy)" [OMIM:Gastroesophageal reflux (infancy)]
OMIM: "Gastroesophageal reflux (less common)" [OMIM:Gastroesophageal reflux (less common)]
OMIM: "Gastroesophageal reflux (rare)" [OMIM:Gastroesophageal reflux (rare)]
OMIM: "Gastroesophageal reflux (uncommon)" [OMIM:Gastroesophageal reflux (uncommon)]
UMLS:C0017168 "Gastroesophageal reflux disease" [Orphanet:27240]
UMLS:C0018834 "Heartburn" [Orphanet:27240]
Is a (Direct Parents):
HPO         Abnormality of the stomach
HPO         Abnormality of the esophagus
MedDRA Gastrointestinal atonic and hypomotility disorders NEC
Orphanet Functional anomalies of the digestive system
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the abdomen(HPO:0001438)
          Abnormality of the abdominal organs(HPO:0002012)
             Abnormality of the gastrointestinal tract(HPO:0011024)
                Abnormality of the stomach(HPO:0002577)
                   Gastroesophageal reflux(HPO:0002020)
                Abnormality of the esophagus(HPO:0002031)
                   Gastroesophageal reflux(HPO:0002020)
MedDRA:
Gastrointestinal disorders(MedDRA:10017947)
    Gastrointestinal motility and defaecation conditions(MedDRA:10017977)
       Gastrointestinal atonic and hypomotility disorders NEC(MedDRA:10017933)
          Gastroesophageal reflux(HPO:0002020)
Database Frequency: 101 / 7739
Resource:

All diseases associated with this symptom:

17p11.2 microduplication syndrome (Orphanet:1713)
1p36 deletion syndrome (Orphanet:1606)
48,XXYY syndrome (Orphanet:10)
AGENESIS OF THE CORPUS CALLOSUM AND CONGENITAL LYMPHEDEMA (OMIM:613623)
Alpha-thalassemia - X-linked intellectual deficit syndrome (Orphanet:847)
Alström syndrome (Orphanet:64)
Aromatic L-amino acid decarboxylase deficiency (Orphanet:35708)
Atrioventricular defect - blepharophimosis -radial defects (Orphanet:1352)
Atypical Rett syndrome (Orphanet:3095)
Autosomal dominant spastic paraplegia type 9 (Orphanet:100990)
Autosomal recessive cutis laxa type 2B (Orphanet:357064)
Autosomal recessive spastic paraplegia type 49 (Orphanet:320385)
Bohring-Opitz syndrome (Orphanet:97297)
Branchio-oculo-facial syndrome (Orphanet:1297)
CARDIOFACIOCUTANEOUS SYNDROME 1 (OMIM:115150)
CONGENITAL CONTRACTURES OF THE LIMBS AND FACE, HYPOTONIA, AND DEVELOPMENTALDELAY (OMIM:616266)
CORNELIA DE LANGE SYNDROME 1 (OMIM:122470)
CORNELIA DE LANGE SYNDROME 2 (OMIM:300590)
CORNELIA DE LANGE SYNDROME 3 (OMIM:610759)
CORNELIA DE LANGE SYNDROME 4 (OMIM:614701)
CORNELIA DE LANGE SYNDROME 5 (OMIM:300882)
CREST syndrome (Orphanet:90290)
Cardiofaciocutaneous syndrome (Orphanet:1340)
Carpenter-Waziri syndrome (Orphanet:93973)
Christianson syndrome (Orphanet:85278)
Chudley-Lowry-Hoar syndrome (Orphanet:93971)
Congenital nephrotic syndrome, Finnish type (Orphanet:839)
Cornelia de Lange syndrome (Orphanet:199)
Costello syndrome (Orphanet:3071)
Craniolenticulosutural dysplasia (Orphanet:50814)
Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies (Orphanet:221145)
DDOST-CDG (Orphanet:300536)
Dubowitz syndrome (Orphanet:235)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 2 (OMIM:300672)
Ear-patella-short stature syndrome (Orphanet:2554)
Emanuel syndrome (Orphanet:96170)
Familial dysautonomia (Orphanet:1764)
Femoral-facial syndrome (Orphanet:1988)
GASTROESOPHAGEAL REFLUX (OMIM:109350)
Gaucher disease type 2 (Orphanet:77260)
Glycogen storage disease due to acid maltase deficiency, infantile onset (Orphanet:308552)
Hereditary sensory and autonomic neuropathy type 1B (Orphanet:139564)
Hereditary sensory and autonomic neuropathy type 2 (Orphanet:970)
Holmes-Gang syndrome (Orphanet:93970)
Hyperinsulinism-hyperammonemia syndrome (Orphanet:35878)
Hyperlysinemia, type I (OMIM:238700)
Hypotonia-speech impairment-severe cognitive delay syndrome (Orphanet:371364)
Idiopathic pulmonary fibrosis (Orphanet:2032)
Infantile dystonia-parkinsonism (Orphanet:238455)
Intellectual deficit, X-linked, Cantagrel type (Orphanet:85277)
Juberg-Marsidi syndrome (Orphanet:93972)
Kleefstra syndrome (Orphanet:261494)
LUBS X-LINKED MENTAL RETARDATION SYNDROME (OMIM:300260)
Leigh syndrome (Orphanet:506)
MACROCEPHALY AND EPILEPTIC ENCEPHALOPATHY (OMIM:606369)
MEIER-GORLIN SYNDROME 1 (OMIM:224690)
MEIER-GORLIN SYNDROME 2 (OMIM:613800)
MEIER-GORLIN SYNDROME 5 (OMIM:613805)
MELAS (Orphanet:550)
Methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency (Orphanet:308425)
Methylmalonic acidemia with homocystinuria, type cblJ (Orphanet:369955)
Microgastria - limb reduction defect (Orphanet:2538)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with variable craniofacial anomalies (Orphanet:369897)
Monosomy 22q13 (Orphanet:48652)
Monosomy 5p (Orphanet:281)
Multiple congenital anomalies - hypotonia - seizures syndrome (Orphanet:280633)
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA (OMIM:201300)
Navajo neurohepatopathy (Orphanet:255229)
Noonan syndrome (Orphanet:648)
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia (Orphanet:363972)
Noonan syndrome-like disorder with loose anagen hair (Orphanet:2701)
Osteopathia striata - cranial sclerosis (Orphanet:2780)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 4 (OMIM:610131)
Pediatric systemic sclerosis (Orphanet:93567)
Pitt-Hopkins syndrome (Orphanet:2896)
Pitt-Hopkins-like syndrome 2 (OMIM:614325)
Pontocerebellar hypoplasia type 8 (Orphanet:324569)
Pontocerebellar hypoplasia, type 9 (OMIM:615809)
Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency (Orphanet:88618)
RETT SYNDROME, CONGENITAL VARIANT (OMIM:613454)
Renier-Gabreels-Jasper syndrome (Orphanet:93975)
Rett syndrome (Orphanet:778)
SLC35A2-CDG (Orphanet:356961)
STEVENSON-CAREY SYNDROME (OMIM:611961)
Severe dermatitis-multiple allergies-metabolic wasting syndrome (Orphanet:369992)
Severe neonatal-onset encephalopathy with microcephaly (Orphanet:209370)
Shprintzen-Goldberg syndrome (Orphanet:2462)
Smith-Fineman-Myers syndrome (Orphanet:93974)
Smith-Lemli-Opitz syndrome (Orphanet:818)
Sudden infant death - dysgenesis of the testes (Orphanet:168593)
Systemic sclerosis (Orphanet:90291)
TENORIO SYNDROME (OMIM:616260)
Thiamine-responsive megaloblastic anemia syndrome (Orphanet:49827)
Timothy syndrome (Orphanet:65283)
Townes-Brocks syndrome (Orphanet:857)
WEBB-DATTANI SYNDROME (OMIM:615926)
Williams syndrome (Orphanet:904)
Wolf-Hirschhorn syndrome (Orphanet:280)
X-linked Opitz G/BBB syndrome (Orphanet:306597)
X-linked intellectual deficit - hypotonic face (Orphanet:73220)
X-linked spinocerebellar ataxia type 3 (Orphanet:85297)