GASTROESOPHAGEAL REFLUX

General Information (adopted from Orphanet):

Synonyms, Signs: GASTROESOPHAGEAL REFLUX DISEASE
GASTROESOPHAGEAL REFLUX, PEDIATRIC
GER
GERD
Number of Symptoms 7
OrphanetNr:
OMIM Id: 109350
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0002020) Gastroesophageal reflux 101 / 7739
2
(HPO:0100580) Barrett esophagus 4 / 7739
3
(HPO:0100633) Esophagitis 7 / 7739
4
(OMIM) Chronic ulcerating esophagitis 1 / 7739
5
(OMIM) Adenocarcinoma of the esophagus risk about 10% 1 / 7739
6
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
7
(OMIM) Columnar epithelium-lined distal esophagus 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Gastroesophageal reflux (GER) is characterized by the retrograde movement of stomach contents into the esophagus. In its most severe form, GER results in extensive tissue damage caused by acid reflux. In adolescents and adults, and even infrequently in ...