GASTROESOPHAGEAL REFLUX
General Information (adopted from Orphanet):
Synonyms, Signs: |
GASTROESOPHAGEAL REFLUX DISEASE GASTROESOPHAGEAL REFLUX, PEDIATRIC GER GERD |
Number of Symptoms | 7 |
OrphanetNr: | |
OMIM Id: |
109350
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ICD-10: |
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UMLs: |
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MeSH: |
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MedDRA: |
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Snomed: |
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Prevalence, inheritance and age of onset:
Prevalence: | No data available. |
Inheritance: |
Autosomal dominant inheritance [Omim] |
Age of onset: |
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Disease classification (adopted from Orphanet):
Parent Diseases: | No data available. |
Symptom Information:
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(HPO:0002020) | Gastroesophageal reflux | 101 / 7739 | ||||
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(HPO:0100580) | Barrett esophagus | 4 / 7739 | ||||
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(HPO:0100633) | Esophagitis | 7 / 7739 | ||||
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(OMIM) | Chronic ulcerating esophagitis | 1 / 7739 | ||||
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(OMIM) | Adenocarcinoma of the esophagus risk about 10% | 1 / 7739 | ||||
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(HPO:0000006) | Autosomal dominant inheritance | 2518 / 7739 | ||||
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(OMIM) | Columnar epithelium-lined distal esophagus | 1 / 7739 |
Associated genes:
ClinVar (via SNiPA)
Gene symbol | Variation | Clinical significance | Reference |
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Additional Information:
Description: (OMIM) |
Gastroesophageal reflux (GER) is characterized by the retrograde movement of stomach contents into the esophagus. In its most severe form, GER results in extensive tissue damage caused by acid reflux. In adolescents and adults, and even infrequently in ... |