Abnormal bleeding

Symptom Information:

Symptom ID: HPO:0001892
Synonyms:
Bleeding diathesis [HPO:0001892]
Bleeding tendency [HPO:0001892]
Hemorrhagic diathesis [HPO:0001892]
Hemostasis disorder [Orphanet:48660]
Prolonged bleeding time [Orphanet:48680]
Hemorrhage [Orphanet:48680]
Blood coagulation disorder (disorder) [Orphanet:48660]
Tendency to bleed (observable entity) [Orphanet:48660]
Disorder of hemostatic system (disorder) [Orphanet:48660]
Bleeding (finding) [Orphanet:48680]
Hemorrhage (morphologic abnormality) [Orphanet:48680]
Blood Coagulation Disorders [Orphanet:48660]
Bleeding tendency [Orphanet:48660]
Bleeding time prolonged [Orphanet:48680]
Abnormal bleeding [OMIM:Abnormal bleeding]
Bleeding diathesis [OMIM:Bleeding diathesis]
Bleeding tendency [OMIM:Bleeding tendency]
Hemorrhagic diathesis [OMIM:Hemorrhagic diathesis]
Clotting/hemostasis disorders [Orphanet:48660]
Hemorrhage/hemorrhagic syndrome/excessive/long-lasting bleeding [Orphanet:48680]
Coagulopathy [Orphanet:48660]
Haemorrhage [Orphanet:48680]
Extravasation blood [Orphanet:48680]
Coagulopathy [MedDRA:10009802]
Clotting [MedDRA:10009802]
Coagulation abnormal [MedDRA:10009802]
Coagulation defects [MedDRA:10009802]
Coagulation defects, other and unspecified [MedDRA:10009802]
Coagulation disorder [MedDRA:10009802]
Coagulation disorder NOS [MedDRA:10009802]
Defect coagulation (NOS) [MedDRA:10009802]
Disorder coagulation [MedDRA:10009802]
Other and unspecified coagulation defects [MedDRA:10009802]
Postpartum coagulation defects [MedDRA:10009802]
Postpartum coagulation defects, postpartum [MedDRA:10009802]
Postpartum coagulation defects, unspecified as to episode of care [MedDRA:10009802]
Postpartum coagulation defects, with delivery [MedDRA:10009802]
Coagulation disorder (NOS) [MedDRA:10009802]
Clotting disorder [MedDRA:10009802]
Acute coagulopathy [MedDRA:10009802]
Haemorrhagic diathesis [MedDRA:10062713]
Bleeding tendency [MedDRA:10062713]
Hemorrhagic diathesis [MedDRA:10062713]
Aggravated bleeding tendency [MedDRA:10062713]
Bleeding time prolonged [MedDRA:10005140]
Bleeding time increased [MedDRA:10005140]
Haemostasis prolonged [MedDRA:10005140]
Hemostasis prolonged [MedDRA:10005140]
Haemorrhage [MedDRA:10055798]
Bleeding [MedDRA:10055798]
Blood loss of (NOS) [MedDRA:10055798]
Haemorrhage NOS [MedDRA:10055798]
Haemorrhage symptom [MedDRA:10055798]
Haemorrhage, unspecified [MedDRA:10055798]
Hemorrhage [MedDRA:10055798]
Hemorrhage (NOS) [MedDRA:10055798]
Hemorrhage term [MedDRA:10055798]
Hemorrhage, unspecified [MedDRA:10055798]
Microhaemorrhage [MedDRA:10055798]
Microhemorrhage [MedDRA:10055798]
Secondary and recurrent haemorrhage as an early complication of trauma [MedDRA:10055798]
Secondary and recurrent hemorrhage as an early complication of trauma [MedDRA:10055798]
Haemorrhage NOS aggravated [MedDRA:10055798]
Hemorrhage aggravated [MedDRA:10055798]
Hemorrhage symptom [MedDRA:10055798]
Uncontrolled haemorrhage [MedDRA:10055798]
Uncontrolled hemorrhage [MedDRA:10055798]
Acute haemorrhage [MedDRA:10055798]
Acute hemorrhage [MedDRA:10055798]
Major bleed [MedDRA:10055798]
Minor bleed [MedDRA:10055798]
Haemorrhage aggravated [MedDRA:10055798]
Extravasation blood [MedDRA:10015867]
Hemorrhagic suffusion [MedDRA:10015867]
Haemorrhagic suffusion [MedDRA:10015867]
Bleeding [OMIM:Bleeding]
Bleeding tendencies [OMIM:Bleeding tendencies]
Bleeding tendency (e.g., epistaxis) [OMIM:Bleeding tendency (e.g., epistaxis)]
Bleeding time prolonged [OMIM:Bleeding time prolonged]
Coagulation defect [OMIM:Coagulation defect]
Coagulation defects [OMIM:Coagulation defects]
Coagulation defects (1 patient) [OMIM:Coagulation defects (1 patient)]
Coagulopathy (INR = 2.2 - 3.5) [OMIM:Coagulopathy (INR = 2.2 - 3.5)]
Hemorrhage [OMIM:Hemorrhage]
Prolonged bleeding time (10 - >30 minutes) [OMIM:Prolonged bleeding time (10 - >30 minutes)]
Prolonged bleeding time (less common) [OMIM:Prolonged bleeding time (less common)]
Bleeding tendencies [MedDRA:10005133]
Coagulopathies [MedDRA:10053567]
Quality:
Cross references:
HPO:0001928 "Abnormality of coagulation" [Orphanet:48660]
HPO:0003010 "Prolonged bleeding time" [Orphanet:48680]
Orphanet:48660 "Clotting/hemostasis disorders" [Orphanet:48660]
Orphanet:48680 "Hemorrhage/hemorrhagic syndrome/excessive/long-lasting bleeding" [Orphanet:48680]
OMIM: "Abnormal bleeding" [OMIM:Abnormal bleeding]
OMIM: "Bleeding diathesis" [OMIM:Bleeding diathesis]
OMIM: "Bleeding tendency" [OMIM:Bleeding tendency]
OMIM: "Hemorrhagic diathesis" [OMIM:Hemorrhagic diathesis]
OMIM: "Bleeding" [OMIM:Bleeding]
OMIM: "Bleeding tendencies" [OMIM:Bleeding tendencies]
OMIM: "Bleeding tendency (e.g., epistaxis)" [OMIM:Bleeding tendency (e.g., epistaxis)]
OMIM: "Bleeding time prolonged" [OMIM:Bleeding time prolonged]
OMIM: "Coagulation defect" [OMIM:Coagulation defect]
OMIM: "Coagulation defects" [OMIM:Coagulation defects]
OMIM: "Coagulation defects (1 patient)" [OMIM:Coagulation defects (1 patient)]
OMIM: "Coagulopathy (INR = 2.2 - 3.5)" [OMIM:Coagulopathy (INR = 2.2 - 3.5)]
OMIM: "Hemorrhage" [OMIM:Hemorrhage]
OMIM: "Prolonged bleeding time (10 - >30 minutes)" [OMIM:Prolonged bleeding time (10 - >30 minutes)]
OMIM: "Prolonged bleeding time (less common)" [OMIM:Prolonged bleeding time (less common)]
UMLS:C0005779 "Blood Coagulation Disorders" [Orphanet:48660]
UMLS:C1458140 "Bleeding tendency" [Orphanet:48660]
UMLS:C0151529 "Bleeding time prolonged" [Orphanet:48680]
UMLS:C0019080 "Hemorrhage" [Orphanet:48680]
Is a (Direct Parents):
MedDRA Coagulopathies and bleeding diatheses (excl thrombocytopenic)
MedDRA Haemorrhages NEC
HPO         Excessive bleeding from superficial cuts
HPO         Abnormality of blood and blood-forming tissues
MedDRA Coagulation and bleeding analyses
Orphanet Abnormality of blood and blood-forming tissues
HPO         Excessive bleeding after a venipuncture
HPO         Oral cavity bleeding
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormal bleeding(HPO:0001892)
MedDRA:
Blood and lymphatic system disorders(MedDRA:10005329)
    Coagulopathies and bleeding diatheses (excl thrombocytopenic)(MedDRA:10064477)
       Abnormal bleeding(HPO:0001892)
Vascular disorders(MedDRA:10047065)
    Vascular haemorrhagic disorders(MedDRA:10047075)
       Haemorrhages NEC(MedDRA:10018987)
          Abnormal bleeding(HPO:0001892)
Investigations(MedDRA:10022891)
    Haematology investigations (incl blood groups)(MedDRA:10018851)
       Coagulation and bleeding analyses(MedDRA:10009728)
          Abnormal bleeding(HPO:0001892)
Database Frequency: 85 / 7739
Resource:

All diseases associated with this symptom:

ADENOMYOSIS (OMIM:600458)
ANTITHROMBIN, FAMILIAL HEMORRHAGIC DIATHESIS DUE TO (OMIM:207300)
ATHROMBIA, ESSENTIAL (OMIM:209050)
Acid phosphatase deficiency (Orphanet:35121)
Aplasia cutis congenita - intestinal lymphangiectasia (Orphanet:1116)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
BERNARD-SOULIER SYNDROME (OMIM:231200)
BLEEDING DISORDER, PLATELET-TYPE, 14 (OMIM:614158)
BLEEDING DISORDER, PLATELET-TYPE, 17 (OMIM:187900)
Body skin hyperlaxity due to vitamin K-dependent coagulation factor deficiency (Orphanet:91135)
CAR FACTOR DEFICIENCY (OMIM:114650)
Combined deficiency of factor V and factor VIII (Orphanet:35909)
Congenital alpha2 antiplasmin deficiency (Orphanet:79)
Congenital factor V deficiency (Orphanet:326)
Congenital factor VII deficiency (Orphanet:327)
Congenital factor X deficiency (Orphanet:328)
Congenital factor XI deficiency (Orphanet:329)
DK1-CDG (Orphanet:91131)
FACTOR V AND FACTOR VIII, COMBINED DEFICIENCY OF, 1 (OMIM:227300)
FACTOR V AND FACTOR VIII, COMBINED DEFICIENCY OF, WITH NORMAL PROTEINC AND PROTEIN C INHIBITOR (OMIM:227310)
FACTOR VIII DEFICIENCY (OMIM:134500)
FACTOR XIII, A SUBUNIT, DEFICIENCY OF (OMIM:613225)
FACTOR XIII, B SUBUNIT, DEFICIENCY OF (OMIM:613235)
FANCONI ANEMIA, COMPLEMENTATION GROUP A (OMIM:227650)
FANCONI ANEMIA, COMPLEMENTATION GROUP C (OMIM:227645)
FANCONI ANEMIA, COMPLEMENTATION GROUP D2 (OMIM:227646)
FECHTNER SYNDROME (OMIM:153640)
FIBRINOLYTIC DEFECT (OMIM:134900)
Familial acute necrotizing encephalopathy (Orphanet:88619)
Fetal Gaucher disease (Orphanet:85212)
GLOBULIN ANOMALY INVOLVING BETA (2A)-GLOBULIN (OMIM:137900)
Gaucher disease (Orphanet:355)
Gaucher disease type 1 (Orphanet:77259)
Gaucher disease type 2 (Orphanet:77260)
Gaucher disease type 3 (Orphanet:77261)
Glycogen storage disease due to glucose-6-phosphatase deficiency (Orphanet:364)
Glycogen storage disease due to glucose-6-phosphatase deficiency type a (Orphanet:79258)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
Gray platelet syndrome (Orphanet:721)
HERMANSKY-PUDLAK SYNDROME 1 (OMIM:203300)
HYPERHEPARINEMIA (OMIM:144050)
Hemophilia A (Orphanet:98878)
Hemophilia B (Orphanet:98879)
Hereditary combined deficiency of vitamin K-dependent clotting factors (Orphanet:98434)
Hermansky-Pudlak syndrome (Orphanet:79430)
Hermansky-Pudlak syndrome with pulmonary fibrosis (Orphanet:231500)
Hermansky-Pudlak syndrome without pulmonary fibrosis (Orphanet:231512)
Immune thrombocytopenic purpura (Orphanet:3002)
Leukocyte adhesion deficiency type III (Orphanet:99844)
MEGDEL syndrome (Orphanet:352328)
MPI-CDG (Orphanet:79319)
MYH9-related thrombocytopenia (Orphanet:182050)
Mediterranean macrothrombocytopenia (Orphanet:101022)
NOONAN SYNDROME 1 (OMIM:163950)
NOONAN SYNDROME 4 (OMIM:610733)
Neonatal hemochromatosis (Orphanet:446)
Noonan syndrome (Orphanet:648)
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia (Orphanet:363972)
P2Y12 defect (Orphanet:36355)
PASSOVOY FACTOR DEFECT (OMIM:168830)
PECHET FACTOR DEFICIENCY (OMIM:169200)
PEROXISOME BIOGENESIS DISORDER 3B (OMIM:266510)
PLATELET DISORDER, UNDEFINED (OMIM:173420)
PLATELET FACTOR 3 DEFICIENCY (OMIM:173450)
PLATELET GLYCOPROTEIN IV DEFICIENCY (OMIM:608404)
PLATELET SIGNAL PROCESSING DEFECT (OMIM:173590)
Paris-Trousseau thrombocytopenia (Orphanet:851)
Platelet storage pool disease (Orphanet:98454)
SLC35A2-CDG (Orphanet:356961)
SRD5A3-CDG (Orphanet:324737)
Scott syndrome (Orphanet:806)
Sitosterolemia (Orphanet:2882)
Stormorken-Sjaastad-Langslet syndrome (Orphanet:3204)
TATSUMI FACTOR DEFICIENCY (OMIM:272650)
THROMBOCYTOPENIA 3 (OMIM:273900)
THROMBOCYTOPENIA WITH ELEVATED SERUM IgA AND RENAL DISEASE (OMIM:314000)
THROMBOCYTOPENIA, CYCLIC (OMIM:188020)
Transaldolase deficiency (Orphanet:101028)
Tyrosinemia type 1 (Orphanet:882)
VISCERAL STEATOSIS, CONGENITAL (OMIM:228100)
VITAMIN K-DEPENDENT CLOTTING FACTORS, COMBINED DEFICIENCY OF, 2 (OMIM:607473)
VON WILLEBRAND DISEASE, X-LINKED FORM (OMIM:314560)
WISKOTT-ALDRICH SYNDROME (OMIM:277970)
Wolfram syndrome 2 (OMIM:604928)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)