Absent speech

Symptom Information:

Symptom ID: HPO:0001344
Synonyms:
Absent speech development [HPO:0001344]
Lack of language development [HPO:0001344]
No speech development [HPO:0001344]
No speech or language development [HPO:0001344]
Absent speech [OMIM:Absent speech]
Lack of language development [OMIM:Lack of language development]
No speech development [OMIM:No speech development]
No speech or language development [OMIM:No speech or language development]
No speech development (in most patients) [OMIM:No speech development (in most patients)]
Quality:
Cross references:
OMIM: "Absent speech" [OMIM:Absent speech]
OMIM: "Lack of language development" [OMIM:Lack of language development]
OMIM: "No speech development" [OMIM:No speech development]
OMIM: "No speech or language development" [OMIM:No speech or language development]
OMIM: "No speech development (in most patients)" [OMIM:No speech development (in most patients)]
Is a (Direct Parents):
HPO         Neurological speech impairment
HPO         Delayed speech and language development
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Abnormality of higher mental function(HPO:0011446)
                Cognitive impairment(HPO:0100543)
                   Delayed speech and language development(HPO:0000750)
                      Absent speech(HPO:0001344)
                Neurological speech impairment(HPO:0002167)
                   Absent speech(HPO:0001344)
MedDRA:
Database Frequency: 57 / 7739
Resource:

All diseases associated with this symptom:

AICARDI-GOUTIERES SYNDROME 7 (OMIM:615846)
ALG11-CDG (Orphanet:280071)
Amish infantile epilepsy syndrome (Orphanet:171714)
Angelman syndrome (Orphanet:72)
Autosomal recessive spastic paraplegia type 18 (Orphanet:209951)
Beta-propeller protein-associated neurodegeneration (Orphanet:329284)
Blepharophimosis-intellectual deficit syndrome due to UBE3B deficiency (Orphanet:329255)
COG4-CDG (Orphanet:263501)
CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 2 (OMIM:615282)
Cabezas syndrome (Orphanet:85293)
Christianson syndrome (Orphanet:85278)
Combined oxidative phosphorylation defect type 13 (Orphanet:319514)
Congenital cataract-hearing loss-severe developmental delay syndrome (Orphanet:300313)
Disorder of sex development - intellectual deficit (Orphanet:2983)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 17 (OMIM:615473)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 27 (OMIM:616139)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 30 (OMIM:616341)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 4 (OMIM:612164)
HYPERPHOSPHATASIA WITH MENTAL RETARDATION SYNDROME 1 (OMIM:239300)
HYPERURICEMIA, INFANTILE, WITH ABNORMAL BEHAVIOR AND NORMAL HYPOXANTHINEGUANINE PHOSPHORIBOSYLTRANSFERASE (OMIM:240000)
Hall-Riggs syndrome (Orphanet:2107)
Hyperphosphatasia-intellectual deficiency syndrome (Orphanet:247262)
Intellectual deficit - alacrima - achalasia (Orphanet:289483)
Intellectual deficit - sparse hair - brachydactyly (Orphanet:3051)
Intellectual deficit, X-linked, Vitale type (Orphanet:85289)
Joubert syndrome 20 (OMIM:614970)
LUBS X-LINKED MENTAL RETARDATION SYNDROME (OMIM:300260)
Lethal ataxia with deafness and optic atrophy (Orphanet:1187)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
MEGDEL syndrome (Orphanet:352328)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 29 (OMIM:616078)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 31 (OMIM:616158)
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 49 (OMIM:616281)
MENTAL RETARDATION, X-LINKED 101 (OMIM:300928)
MENTAL RETARDATION, X-LINKED 91 (OMIM:300577)
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 4 (OMIM:615159)
MPDU1-CDG (Orphanet:79323)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 14 (OMIM:615350)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 1 (OMIM:613155)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 14 (OMIM:615351)
Microcephaly - facio-cardio-skeletal syndrome, Hadziselimovic type (Orphanet:217026)
Microcephaly-cerebellar hypoplasia-cardiac conduction defect syndrome (Orphanet:329332)
Microphthalmia with brain and digit anomalies (Orphanet:139471)
Mowat-Wilson syndrome (Orphanet:2152)
Mucolipidosis type 4 (Orphanet:578)
Multiple congenital anomalies-hypotonia-seizures syndrome type 2 (Orphanet:300496)
OPTICOCOCHLEODENTATE DEGENERATION (OMIM:258700)
OROFACIODIGITAL SYNDROME XIV (OMIM:615948)
PONTOCEREBELLAR HYPOPLASIA, TYPE 10 (OMIM:615803)
PONTOCEREBELLAR HYPOPLASIA, TYPE 1B (OMIM:614678)
Pitt-Hopkins syndrome (Orphanet:2896)
Pontine tegmental cap dysplasia (Orphanet:269229)
Pontocerebellar hypoplasia type 8 (Orphanet:324569)
Sanfilippo syndrome type D (Orphanet:79272)
Transketolase deficiency (ORPHA:488618)
X-linked intellectual deficit, Najm type (Orphanet:163937)
X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome (Orphanet:324410)