Symptom Information: Sort according to HPO 

1
 (HPO:0001639) Hypertrophic cardiomyopathy Very frequent [IBIS] 100% (n=8) 23929671 IBIS 137 / 7739
2
 (HPO:0003128) Lactic acidosis Very frequent [IBIS] 100% (n=8) 23929671 IBIS 116 / 7739
3
 (HPO:0001252) Muscular hypotonia Frequent [IBIS] 50% (n=8) 23929671 IBIS 990 / 7739
4
 (HPO:0003348) Hyperalaninemia Frequent [IBIS] 37.5% (n=8) 23929671 IBIS 19 / 7739
5
 (HPO:0001263) Global developmental delay Occasional [IBIS] 25% (n=8) 23929671 IBIS 853 / 7739
6
 (HPO:0001270) Motor delay Occasional [IBIS] 25% (n=8) 23929671 IBIS 322 / 7739
7
 (HPO:0001508) Failure to thrive Occasional [IBIS] 25% (n=8) 23929671 IBIS 454 / 7739
8
 (HPO:0011968) Feeding difficulties Occasional [IBIS] 25% (n=8) 23929671 IBIS 240 / 7739
9
 (HPO:0000648) Optic atrophy Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 238 / 7739
10
 (HPO:0001250) Seizures Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 1245 / 7739
11
 (HPO:0001332) Dystonia Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 197 / 7739
12
 (HPO:0001943) Hypoglycemia Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 131 / 7739
13
 (HPO:0011951) Aspiration pneumonia Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 6 / 7739
14
 (HPO:0001298) Encephalopathy Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 72 / 7739
15
 (HPO:0001716) Wolff-Parkinson-White syndrome Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 21 / 7739
16
 (HPO:0001649) Tachycardia Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 53 / 7739
17
 (HPO:0001688) Sinus bradycardia Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 18 / 7739
18
 (HPO:0002919) Ketonuria Occasional [IBIS] 12.5% (n=8) 23929671 IBIS 18 / 7739
19
 (HPO:0008947) Infantile muscular hypotonia Very frequent 100% (n=8) 23929671 IBIS 482 / 7739
20
 (OMIM) Lack of ocular fixation (1 patient) Occasional 12.5% (n=8) 23929671 IBIS 1 / 7739
21
 (HPO:0001324) Muscle weakness Occasional 12.5% (n=8) 23929671 IBIS 859 / 7739
22
 (HPO:0001510) Growth delay 22608499 IBIS 295 / 7739
23
 (HPO:0001518) Small for gestational age 22608499 IBIS 107 / 7739
24
 (HPO:0001942) Metabolic acidosis 22608499 IBIS 81 / 7739
25
 (HPO:0002151) Increased serum lactate 22608499 IBIS 92 / 7739
26
 (HPO:0011675) Arrhythmia 22608499 IBIS 226 / 7739
27
 (OMIM) Variable deficiencies of mitochondrial respiratory chain complexes I, III, and IV 22608499 IBIS 1 / 7739
28
 (OMIM) T2-weighted hyperintensities in deep brain regions 23929671 IBIS 1 / 7739
29
 (HPO:0008972) Decreased activity of mitochondrial respiratory chain 23929671 IBIS 34 / 7739
30
 (HPO:0001635) Congestive heart failure 22608499 IBIS 232 / 7739