Symptom Information: Sort according to HPO 

1
 (HPO:0000733) Stereotypy Occasional [Orphanet] 58 / 7739
2
 (HPO:0011968) Feeding difficulties 240 / 7739
3
 (HPO:0002007) Frontal bossing Frequent [Orphanet] 366 / 7739
4
 (HPO:0001252) Muscular hypotonia Frequent [Orphanet] 990 / 7739
5
 (HPO:0001324) Muscle weakness 859 / 7739
6
 (HPO:0000358) Posteriorly rotated ears 163 / 7739
7
 (HPO:0000369) Low-set ears 372 / 7739
8
 (HPO:0000276) Long face Occasional [Orphanet] 109 / 7739
9
 (HPO:0000957) Cafe-au-lait spot Frequent [Orphanet] 84 / 7739
10
 (HPO:0000445) Wide nose Occasional [Orphanet] 190 / 7739
11
 (HPO:0000347) Micrognathia 426 / 7739
12
 (HPO:0000202) Oral cleft Occasional [Orphanet] 120 / 7739
13
 (HPO:0000494) Downslanted palpebral fissures Very frequent [Orphanet] 328 / 7739
14
 (HPO:0007021) Pain insensitivity Frequent [Orphanet] 35 / 7739
15
 (HPO:0011675) Arrhythmia Occasional [Orphanet] 226 / 7739
16
 (HPO:0000490) Deeply set eye Frequent [Orphanet] 131 / 7739
17
 (HPO:0000348) High forehead Occasional [Orphanet] 157 / 7739
18
 (HPO:0000365) Hearing impairment Occasional [Orphanet] rare [HPO:skoehler] 539 / 7739
19
 (HPO:0000389) Chronic otitis media Very frequent [Orphanet] 64 / 7739
20
 (HPO:0000463) Anteverted nares Occasional [Orphanet] 305 / 7739
21
 (HPO:0001770) Toe syndactyly Frequent [Orphanet] 149 / 7739
22
 (HPO:0003196) Short nose Occasional [Orphanet] 264 / 7739
23
 (HPO:0100490) Camptodactyly of finger Frequent [Orphanet] 212 / 7739
24
 (HPO:0002104) Apnea Occasional [Orphanet] 106 / 7739
25
 (HPO:0000954) Single transverse palmar crease Frequent [Orphanet] 162 / 7739
26
 (HPO:0004322) Short stature Frequent [Orphanet] rare [HPO:skoehler] 1232 / 7739
27
 (HPO:0000486) Strabismus Occasional [Orphanet] 576 / 7739
28
 (HPO:0000194) Open mouth Frequent [Orphanet] 70 / 7739
29
 (HPO:0002360) Sleep disturbance Occasional [Orphanet] 113 / 7739
30
 (HPO:0004279) Short palm Occasional [Orphanet] 323 / 7739
31
 (HPO:0000286) Epicanthus Frequent [Orphanet] 371 / 7739
32
 (HPO:0000601) Hypotelorism Occasional [Orphanet] 83 / 7739
33
 (HPO:0009623) Proximal placement of thumb Occasional [Orphanet] 50 / 7739
34
 (HPO:0000414) Bulbous nose 63 / 7739
35
 (HPO:0001249) Intellectual disability 1089 / 7739
36
 (HPO:0001263) Global developmental delay 853 / 7739
37
 (HPO:0012368) Flat face Frequent [Orphanet] 106 / 7739
38
 (HPO:0000218) High palate 356 / 7739
39
 (HPO:0000219) Thin upper lip vermilion 112 / 7739
40
 (HPO:0001511) Intrauterine growth retardation rare [HPO:skoehler] 358 / 7739
41
 (HPO:0001702) Abnormality of the tricuspid valve Occasional [Orphanet] 32 / 7739
42
 (HPO:0002167) Neurological speech impairment Frequent [Orphanet] 308 / 7739
43
 (HPO:0012385) Camptodactyly 113 / 7739
44
 (OMIM) Recurrent ear infections 3 / 7739
45
 (OMIM) Small eyes 3 / 7739
46
 (OMIM) Congenital cardiac defects (less common) 1 / 7739
47
 (MedDRA:10058668) Clinodactyly 91 / 7739
48
 (MedDRA:10072883) Brachydactyly 153 / 7739
49
 (OMIM) Severe speech impairment 1 / 7739
50
 (HPO:0008947) Infantile muscular hypotonia 482 / 7739
51
 (HPO:0010547) Muscle flaccidity 466 / 7739
52
 (OMIM) No autism 1 / 7739
53
 (HPO:0002577) Abnormality of the stomach Very frequent [Orphanet] 84 / 7739
54
 (HPO:0000277) Abnormality of the mandible Frequent [Orphanet] 394 / 7739
55
 (HPO:0005105) Abnormal nasal morphology Occasional [Orphanet] 114 / 7739
56
 (HPO:0100851) Abnormal emotion/affect behavior Frequent [Orphanet] 85 / 7739
57
 (HPO:0012758) Neurodevelopmental delay Very frequent [Orphanet] 949 / 7739
58
 (HPO:0004325) Decreased body weight Very frequent [Orphanet] 492 / 7739
59
 (HPO:0003220) Abnormality of chromosome stability Very frequent [Orphanet] 98 / 7739
60
 (HPO:0000357) Abnormal location of ears Frequent [Orphanet] 328 / 7739
61
 (HPO:0001156) Brachydactyly syndrome 180 / 7739
62
 (HPO:0003812) Phenotypic variability 129 / 7739
63
 (HPO:0030084) Clinodactyly 90 / 7739