|
1
|
(HPO:0002205)
|
Recurrent respiratory infections |
|
|
|
|
254 / 7739
|
|
2
|
(HPO:0002716)
|
Lymphadenopathy |
|
|
|
|
129 / 7739
|
|
3
|
(HPO:0002718)
|
Recurrent bacterial infections |
|
|
|
|
75 / 7739
|
|
4
|
(HPO:0002721)
|
Immunodeficiency |
|
|
|
|
97 / 7739
|
|
5
|
(HPO:0002720)
|
IgA deficiency |
|
|
|
|
33 / 7739
|
|
6
|
(HPO:0002959)
|
Impaired Ig class switch recombination |
|
|
|
|
5 / 7739
|
|
7
|
(HPO:0004315)
|
IgG deficiency |
|
|
|
|
38 / 7739
|
|
8
|
(HPO:0004798)
|
Recurrent infection of the gastrointestinal tract |
|
|
|
|
9 / 7739
|
|
9
|
(HPO:0200117)
|
Recurrent upper and lower respiratory tract infections |
|
|
|
|
4 / 7739
|
|
10
|
(OMIM)
|
Low-absent IgG, IgA |
|
|
|
|
1 / 7739
|
|
11
|
(OMIM)
|
Normal-elevated IgM |
|
|
|
|
1 / 7739
|
|
12
|
(OMIM)
|
Giant germinal centers in lymph nodes |
|
|
|
|
1 / 7739
|
|
13
|
(OMIM)
|
B-cell count normal |
|
|
|
|
4 / 7739
|
|
14
|
(OMIM)
|
Defective generation of somatic hypermutations (SHM) |
|
|
|
|
1 / 7739
|
|
15
|
(HPO:0000007)
|
Autosomal recessive inheritance |
|
|
|
|
2538 / 7739
|