Impaired Ig class switch recombination

Symptom Information:

Symptom ID: HPO:0002959
Synonyms:
Impaired B-lymphocyte isotype switching [HPO:0002959]
Impaired Ig class-switch recombination (CSR) [HPO:0002959]
Impaired Ig class-switch recombination (CSR) [OMIM:Impaired Ig class-switch recombination (CSR)]
Impaired Ig class switch recombination (CSR) [OMIM:Impaired Ig class switch recombination (CSR)]
Quality:
Cross references:
OMIM: "Impaired Ig class-switch recombination (CSR)" [OMIM:Impaired Ig class-switch recombination (CSR)]
OMIM: "Impaired Ig class switch recombination (CSR)" [OMIM:Impaired Ig class switch recombination (CSR)]
Is a (Direct Parents):
HPO         Abnormality of B cell physiology
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of cellular immune system(HPO:0010987)
             Abnormality of leukocytes(HPO:0001881)
                Abnormality of lymphocytes(HPO:0004332)
                   Abnormality of B cells(HPO:0002846)
                      Abnormality of B cell physiology(HPO:0005372)
                         Impaired Ig class switch recombination(HPO:0002959)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of leukocytes(HPO:0001881)
             Abnormality of lymphocytes(HPO:0004332)
                Abnormality of B cells(HPO:0002846)
                   Abnormality of B cell physiology(HPO:0005372)
                      Impaired Ig class switch recombination(HPO:0002959)
MedDRA:
Database Frequency: 5 / 7739
Resource:

All diseases associated with this symptom:

Hyper-IgM syndrome type 2 (Orphanet:101089)
Hyper-IgM syndrome type 3 (Orphanet:101090)
Hyper-IgM syndrome type 4 (Orphanet:101091)
Hyper-IgM syndrome type 5 (Orphanet:101092)
X-linked hyper-IgM syndrome (Orphanet:101088)