1
|
(HPO:0003281)
|
Increased serum ferritin |
Very frequent [IBIS]
4/4 [HPO]
|
|
14982867; 15138164; 20234129; 18492090; 17768121; 17339196; 15315789; 15710580; 15967692; 16099526; 24584909
|
IBIS
|
32 / 7739
|
2
|
(HPO:0003452)
|
Increased serum iron |
Very frequent [IBIS]
7/7 [HPO]
|
|
14982867; 15138164; 15710580
|
IBIS
|
5 / 7739
|
3
|
(HPO:0012463)
|
Elevated transferrin saturation |
Very frequent [IBIS]
|
|
14982867; 15138164; 20234129; 18492090; 17768121; 17339196; 15315789; 15710580; 15967692; 16099526; 24584909
|
IBIS
|
10 / 7739
|
4
|
(HPO:0011031)
|
Abnormality of iron homeostasis |
Very frequent [IBIS]
|
|
14982867
|
IBIS
|
16 / 7739
|
5
|
(HPO:0000044)
|
Hypogonadotrophic hypogonadism |
|
|
14982867; 15997423; 19796184; 15138164; 17768121; 15315789; 15710580; 15967692; 16424663
|
IBIS
|
56 / 7739
|
6
|
(HPO:0000953)
|
Hyperpigmentation of the skin |
|
|
14982867; 15138164; 16099526; 24584909
|
IBIS
|
75 / 7739
|
7
|
(HPO:0001394)
|
Cirrhosis |
|
|
14982867; 18492090; 15710580; 16099526; 24584909
|
IBIS
|
102 / 7739
|
8
|
(HPO:0001638)
|
Cardiomyopathy |
|
|
14982867; 15611318; 19796184; 24584909
|
IBIS
|
192 / 7739
|
9
|
(HPO:0002240)
|
Hepatomegaly |
|
|
14982867; 15611318; 15138164; 18492090; 17768121
|
IBIS
|
467 / 7739
|
10
|
(HPO:0000141)
|
Amenorrhea |
|
|
14982867; 16424663
|
IBIS
|
16 / 7739
|
11
|
(HPO:0002027)
|
Abdominal pain |
|
|
15611318
|
IBIS
|
184 / 7739
|
12
|
(HPO:0004755)
|
Supraventricular tachycardia |
|
|
15611318
|
IBIS
|
20 / 7739
|
13
|
(HPO:0002094)
|
Dyspnea |
|
|
15611318; 15138164; 16099526; 24584909
|
IBIS
|
132 / 7739
|
14
|
(HPO:0000802)
|
Impotence |
|
|
15997423
|
IBIS
|
20 / 7739
|
15
|
(HPO:0002215)
|
Sparse axillary hair |
|
|
15997423
|
IBIS
|
21 / 7739
|
16
|
(HPO:0002225)
|
Sparse pubic hair |
|
|
15997423
|
IBIS
|
76 / 7739
|
17
|
(HPO:0008230)
|
Decreased testosterone in males |
|
|
15997423; 24584909
|
IBIS
|
4 / 7739
|
18
|
(HPO:0008213)
|
Gonadotropin deficiency |
|
|
15997423
|
IBIS
|
6 / 7739
|
19
|
(HPO:0004349)
|
Reduced bone mineral density |
|
|
15997423
|
IBIS
|
165 / 7739
|
20
|
(HPO:0002797)
|
Osteolysis |
|
|
15997423
|
IBIS
|
68 / 7739
|
21
|
(HPO:0000939)
|
Osteoporosis |
|
|
15997423; 15710580
|
IBIS
|
129 / 7739
|
22
|
(HPO:0001663)
|
Ventricular fibrillation |
|
|
19796184
|
IBIS
|
35 / 7739
|
23
|
(HPO:0001541)
|
Ascites |
|
|
19796184
|
IBIS
|
94 / 7739
|
24
|
(HPO:0005110)
|
Atrial fibrillation |
|
|
19796184; 15138164; 16424663
|
IBIS
|
71 / 7739
|
25
|
(HPO:0011675)
|
Arrhythmia |
|
|
19796184; 24584909
|
IBIS
|
226 / 7739
|
26
|
(HPO:0001635)
|
Congestive heart failure |
|
|
19796184; 15315789; 15967692; 16424663; 24584909
|
IBIS
|
232 / 7739
|
27
|
(HPO:0001962)
|
Palpitations |
|
|
15138164
|
IBIS
|
62 / 7739
|
28
|
(HPO:0100749)
|
Chest pain |
|
|
15138164
|
IBIS
|
92 / 7739
|
29
|
(HPO:0003765)
|
Psoriasis |
|
|
15138164
|
IBIS
|
17 / 7739
|
30
|
(HPO:0000869)
|
Secondary amenorrhea |
|
|
15138164
|
IBIS
|
42 / 7739
|
31
|
(HPO:0001644)
|
Dilated cardiomyopathy |
|
|
15138164; 15967692; 15710580
|
IBIS
|
141 / 7739
|
32
|
(HPO:0003074)
|
Hyperglycemia |
|
|
15138164; 16099526
|
IBIS
|
37 / 7739
|
33
|
(HPO:0002910)
|
Elevated hepatic transaminases |
|
|
15138164; 18492090; 24584909
|
IBIS
|
158 / 7739
|
34
|
(HPO:0001395)
|
Hepatic fibrosis |
|
|
15138164
|
IBIS
|
67 / 7739
|
35
|
(HPO:0000819)
|
Diabetes mellitus |
|
|
15138164; 15967692; 16099526; 24584909
|
IBIS
|
131 / 7739
|
36
|
(HPO:0012465)
|
Elevated hepatic iron concentration |
|
|
20234129; 18492090
|
IBIS
|
8 / 7739
|
37
|
(HPO:0006253)
|
Swelling of proximal interphalangeal joints |
|
|
20234129
|
IBIS
|
3 / 7739
|
38
|
(HPO:0000140)
|
Abnormality of the menstrual cycle |
|
|
20234129
|
IBIS
|
7 / 7739
|
39
|
(HPO:0003270)
|
Abdominal distention |
|
|
18492090
|
IBIS
|
46 / 7739
|
40
|
(HPO:0001744)
|
Splenomegaly |
|
|
18492090
|
IBIS
|
337 / 7739
|
41
|
(HPO:0001009)
|
Telangiectasia |
|
|
18492090
|
IBIS
|
46 / 7739
|
42
|
(HPO:0001409)
|
Portal hypertension |
|
|
18492090
|
IBIS
|
39 / 7739
|
43
|
(HPO:0001324)
|
Muscle weakness |
|
|
17768121
|
IBIS
|
859 / 7739
|
44
|
(HPO:0002829)
|
Arthralgia |
|
|
17768121; 15710580
|
IBIS
|
79 / 7739
|
45
|
(HPO:0001413)
|
Micronodular cirrhosis |
|
|
17768121; 15967692
|
IBIS
|
11 / 7739
|
46
|
(HPO:0005162)
|
Left ventricular failure |
|
|
15315789
|
IBIS
|
18 / 7739
|
47
|
(HPO:0006580)
|
Portal fibrosis |
|
|
15315789
|
IBIS
|
10 / 7739
|
48
|
(HPO:0000786)
|
Primary amenorrhea |
|
|
15315789
|
IBIS
|
61 / 7739
|
49
|
(HPO:0000871)
|
Panhypopituitarism |
|
|
15710580
|
IBIS
|
8 / 7739
|
50
|
(HPO:0004322)
|
Short stature |
|
|
15710580
|
IBIS
|
1232 / 7739
|
51
|
(HPO:0000823)
|
Delayed puberty |
|
|
15710580
|
IBIS
|
65 / 7739
|
52
|
(HPO:0001254)
|
Lethargy |
|
|
15710580
|
IBIS
|
104 / 7739
|
53
|
(HPO:0002758)
|
Osteoarthritis |
|
|
15710580
|
IBIS
|
78 / 7739
|
54
|
(HPO:0001410)
|
Decreased liver function |
|
|
15710580; 16424663
|
IBIS
|
59 / 7739
|
55
|
(HPO:0002875)
|
Exertional dyspnea |
|
|
15967692
|
IBIS
|
29 / 7739
|
56
|
(HPO:0010741)
|
Edema of the lower limbs |
|
|
15967692
|
IBIS
|
34 / 7739
|
57
|
(HPO:0004751)
|
Paroxysmal ventricular tachycardia |
|
|
15967692
|
IBIS
|
5 / 7739
|
58
|
(HPO:0002615)
|
Hypotension |
|
|
15967692
|
IBIS
|
52 / 7739
|
59
|
(HPO:0003076)
|
Glycosuria |
|
|
16099526
|
IBIS
|
32 / 7739
|
60
|
(HPO:0001824)
|
Weight loss |
|
|
16424663
|
IBIS
|
42 / 7739
|
61
|
(HPO:0012569)
|
Delayed menarche |
|
|
16424663
|
IBIS
|
5 / 7739
|
62
|
(HPO:0001723)
|
Restrictive cardiomyopathy |
|
|
16424663
|
IBIS
|
22 / 7739
|
63
|
(HPO:0004396)
|
Poor appetite |
|
|
24584909
|
IBIS
|
7 / 7739
|
64
|
(HPO:0012378)
|
Fatigue |
|
|
24584909
|
IBIS
|
50 / 7739
|
65
|
(HPO:0004756)
|
Ventricular tachycardia |
|
|
24584909
|
IBIS
|
55 / 7739
|