Nail dystrophy

Symptom Information:

Symptom ID: HPO:0008404
Synonyms:
Dystrophic nails [HPO:0008404]
Onychodystrophy [HPO:0008404]
Dystrophia unguium [HPO:0008404]
Dystrophic nails [OMIM:Dystrophic nails]
Nail dystrophy [OMIM:Nail dystrophy]
Onychodystrophy [OMIM:Onychodystrophy]
Nail dystrophy [MedDRA:10028698]
Onychodystrophy [MedDRA:10028698]
Dystrophic nails (in some patients) [OMIM:Dystrophic nails (in some patients)]
Dystrophic nails (less common) [OMIM:Dystrophic nails (less common)]
Dystrophic nails (spooned, grooves) [OMIM:Dystrophic nails (spooned, grooves)]
Nail dystrophy (1 patient) [OMIM:Nail dystrophy (1 patient)]
Nail dystrophy (92% male patients) [OMIM:Nail dystrophy (92% male patients)]
Nail dystrophy (classic feature, NOLA3 patient) [OMIM:Nail dystrophy (classic feature, NOLA3 patient)]
Nail dystrophy (in some patients) [OMIM:Nail dystrophy (in some patients)]
Nail dystrophy (less common) [OMIM:Nail dystrophy (less common)]
Nail dystrophy (onset in childhood or adolescence) [OMIM:Nail dystrophy (onset in childhood or adolescence)]
Nail dystrophy (seen in recessive form) [OMIM:Nail dystrophy (seen in recessive form)]
Onychodystrophy (in some patients) [OMIM:Onychodystrophy (in some patients)]
Onychodystrophy (rare) [OMIM:Onychodystrophy (rare)]
Quality:
Cross references:
OMIM: "Dystrophic nails" [OMIM:Dystrophic nails]
OMIM: "Nail dystrophy" [OMIM:Nail dystrophy]
OMIM: "Onychodystrophy" [OMIM:Onychodystrophy]
OMIM: "Dystrophic nails (in some patients)" [OMIM:Dystrophic nails (in some patients)]
OMIM: "Dystrophic nails (less common)" [OMIM:Dystrophic nails (less common)]
OMIM: "Dystrophic nails (spooned, grooves)" [OMIM:Dystrophic nails (spooned, grooves)]
OMIM: "Nail dystrophy (1 patient)" [OMIM:Nail dystrophy (1 patient)]
OMIM: "Nail dystrophy (92% male patients)" [OMIM:Nail dystrophy (92% male patients)]
OMIM: "Nail dystrophy (classic feature, NOLA3 patient)" [OMIM:Nail dystrophy (classic feature, NOLA3 patient)]
OMIM: "Nail dystrophy (in some patients)" [OMIM:Nail dystrophy (in some patients)]
OMIM: "Nail dystrophy (less common)" [OMIM:Nail dystrophy (less common)]
OMIM: "Nail dystrophy (onset in childhood or adolescence)" [OMIM:Nail dystrophy (onset in childhood or adolescence)]
OMIM: "Nail dystrophy (seen in recessive form)" [OMIM:Nail dystrophy (seen in recessive form)]
OMIM: "Onychodystrophy (in some patients)" [OMIM:Onychodystrophy (in some patients)]
OMIM: "Onychodystrophy (rare)" [OMIM:Onychodystrophy (rare)]
Is a (Direct Parents):
HPO         Abnormality of the nail
MedDRA Nail and nail bed conditions (excl infections and infestations)
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of skin adnexa(HPO:0011138)
             Abnormality of the nail(HPO:0001597)
                Nail dystrophy(HPO:0008404)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Skin appendage conditions(MedDRA:10040798)
       Nail and nail bed conditions (excl infections and infestations)(MedDRA:10028685)
          Nail dystrophy(HPO:0008404)
Database Frequency: 89 / 7739
Resource:

All diseases associated with this symptom:

17q12 microdeletion syndrome (Orphanet:261265)
ANGIOMA SERPIGINOSUM, X-LINKED (OMIM:300652)
ANONYCHIA-ONYCHODYSTROPHY WITH BRACHYDACTYLY TYPE B AND ECTRODACTYLY (OMIM:106990)
Ankyloblepharon - ectodermal defects - cleft lip/palate (Orphanet:1071)
Autosomal recessive deafness-onychodystrophy syndrome (Orphanet:79500)
Autosomal recessive palmoplantar keratoderma and congenital alopecia (Orphanet:1366)
BRESEK syndrome (Orphanet:85284)
Bathing suit ichthyosis (Orphanet:100976)
CATARACTS, CONGENITAL, WITH SENSORINEURAL DEAFNESS, DOWN SYNDROME-LIKEFACIAL APPEARANCE, SHORT STATURE, AND MENTAL RETARDATION (OMIM:601088)
Cardiofaciocutaneous syndrome (Orphanet:1340)
Congenital anonychia (Orphanet:79143)
Congenital nephrotic syndrome-interstitial lung disease-epidermolysis bullosa syndrome (Orphanet:306504)
Cooks syndrome (Orphanet:1487)
Corneal intraepithelial dyskeratosis with palmoplantar hyperkeratosis and laryngeal dyskeratosis (Orphanet:352662)
Cronkhite-Canada syndrome (Orphanet:2930)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 1 (OMIM:127550)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 2 (OMIM:613989)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 1 (OMIM:224230)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 2 (OMIM:613987)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 3 (OMIM:613988)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 5 (OMIM:615190)
Deafness - onychodystrophy (Orphanet:3231)
Deafness - onychodystrophy, autosomal dominant (Orphanet:79499)
Dermatoosteolysis, Kirghizian type (Orphanet:1657)
Dermatopathia pigmentosa reticularis (Orphanet:86920)
Disseminated superficial actinic porokeratosis (Orphanet:79152)
Distal limb deficiencies - micrognathia syndrome (Orphanet:1307)
Dyschromatosis universalis hereditaria 1 (OMIM:127500)
Dyschromatosis universalis hereditaria 2 (OMIM:612715)
Dyschromatosis universalis hereditaris 3 (OMIM:615402)
Dyskeratosis congenita (Orphanet:1775)
Dystrophic epidermolysis bullosa pruriginosa (Orphanet:89843)
ECTODERMAL DYSPLASIA 4, HAIR/NAIL TYPE (OMIM:602032)
ECTODERMAL DYSPLASIA 9, HAIR/NAIL TYPE (OMIM:614931)
ECTODERMAL DYSPLASIA/SHORT STATURE SYNDROME (OMIM:616029)
ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME3 (OMIM:604292)
EPIDERMOLYSIS BULLOSA DYSTROPHICA NEUROTROPHICA (OMIM:226500)
EPIDERMOLYSIS BULLOSA SIMPLEX, AUTOSOMAL RECESSIVE 2 (OMIM:615425)
EPIDERMOLYSIS BULLOSA WITH CONGENITAL LOCALIZED ABSENCE OF SKIN ANDDEFORMITY OF NAILS (OMIM:132000)
Epidermolysis bullosa simplex with mottled pigmentation (Orphanet:79397)
Epidermolysis bullosa simplex with muscular dystrophy (Orphanet:257)
Epidermolysis bullosa simplex, Dowling-Meara type (Orphanet:79396)
Focal dermal hypoplasia (Orphanet:2092)
Generalized dominant dystrophic epidermolysis bullosa (Orphanet:231568)
Generalized epidermolysis bullosa simplex, non-Dowling-Meara type (Orphanet:79399)
Generalized junctional epidermolysis bullosa, non-Herlitz type (Orphanet:79402)
Generalized pustular psoriasis (Orphanet:247353)
Hereditary mucoepithelial dysplasia (Orphanet:1839)
Hereditary sensory and autonomic neuropathy type 4 (Orphanet:642)
Hidrotic ectodermal dysplasia (Orphanet:189)
Hidrotic ectodermal dysplasia, Christianson-Fourie type (Orphanet:1808)
Hoyeraal-Hreidarsson syndrome (Orphanet:3322)
IMMUNODEFICIENCY, COMMON VARIABLE, 10 (OMIM:615577)
Ichthyosis follicularis - alopecia - photophobia (Orphanet:2273)
Incontinentia pigmenti (Orphanet:464)
Intellectual deficit, X-linked, Nascimento type (Orphanet:163956)
Junctional epidermolysis bullosa - pyloric atresia (Orphanet:79403)
Junctional epidermolysis bullosa inversa (Orphanet:79405)
Junctional epidermolysis bullosa, Herlitz type (Orphanet:79404)
Junctional epidermolysis bullosa, non-Herlitz type (Orphanet:89840)
KERATOSIS FOLLICULARIS SPINULOSA DECALVANS, AUTOSOMAL DOMINANT (OMIM:612843)
KERATOSIS FOLLICULARIS SPINULOSA DECALVANS, X-LINKED (OMIM:308800)
KID syndrome (Orphanet:477)
Keratosis linearis-ichthyosis congenita-sclerosing keratoderma syndrome (Orphanet:281201)
Localized junctional epidermolysis bullosa, non-Herlitz type (Orphanet:251393)
Mammary-digital-nail syndrome (Orphanet:238744)
Monilethrix (Orphanet:573)
Mutilating palmoplantar keratoderma with periorificial keratotic plaques (Orphanet:659)
NAIL DISORDER, NONSYNDROMIC CONGENITAL, 6 (OMIM:107000)
NEUROPATHY, HEREDITARY SENSORY, TYPE ID (OMIM:613708)
Naxos disease (Orphanet:34217)
Nephrotic syndrome-deafness-pretibial epidermolysis bullosa syndrome (Orphanet:300333)
Odonto-tricho-ungual-digito-palmar syndrome (Orphanet:69082)
Otopalatodigital syndrome type 1 (Orphanet:90650)
PACHYONYCHIA CONGENITA 2 (OMIM:167210)
PACHYONYCHIA CONGENITA 3 (OMIM:615726)
PACHYONYCHIA CONGENITA 4 (OMIM:615728)
PSORIASIS 15, PUSTULAR, SUSCEPTIBILITY TO (OMIM:616106)
Palmoplantar keratoderma-spastic paralysis syndrome (Orphanet:2201)
Pure hair and nail ectodermal dysplasia (Orphanet:69084)
Recessive dystrophic epidermolysis bullosa inversa (Orphanet:79409)
Retinopathy - anemia- central nervous system anomalies (Orphanet:3088)
SABINAS BRITTLE HAIR SYNDROME (OMIM:211390)
STING-ASSOCIATED VASCULOPATHY, INFANTILE-ONSET (OMIM:615934)
Severe generalized recessive dystrophic epidermolysis bullosa (Orphanet:79408)
Skin fragility-woolly hair-palmoplantar keratoderma syndrome (Orphanet:293165)
Tangier disease (Orphanet:31150)
Transient bullous dermolysis of the newborn (Orphanet:79411)
Tricho-odonto-onychial dysplasia (Orphanet:3355)