Decreased activity of mitochondrial complex II

Symptom Information:

Symptom ID: HPO:0008314
Synonyms:
Respiratory complex II deficiency [HPO:0008314]
Decreased activity of mitochondrial complex II (succinate dehydrogenase) [OMIM:Decreased activity of mitochondrial complex II (succinate dehydrogenase)]
Quality:
Cross references:
OMIM: "Decreased activity of mitochondrial complex II (succinate dehydrogenase)" [OMIM:Decreased activity of mitochondrial complex II (succinate dehydrogenase)]
Is a (Direct Parents):
HPO         Decreased activity of mitochondrial respiratory chain
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of metabolism/homeostasis(HPO:0001939)
          Abnormality of cell physiology(HPO:0011017)
             Abnormality of the mitochondrion(HPO:0012103)
                Abnormality of mitochondrial metabolism(HPO:0003287)
                   Abnormal activity of mitochondrial respiratory chain(HPO:0011922)
                      Decreased activity of mitochondrial respiratory chain(HPO:0008972)
                         Decreased activity of mitochondrial complex II(HPO:0008314)
MedDRA:
Database Frequency: 7 / 7739
Resource:

All diseases associated with this symptom:

Cardiomyopathy, dilated, 1GG (OMIM:613642)
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome (Orphanet:319678)
Hereditary myopathy with lactic acidosis due to ISCU deficiency (Orphanet:43115)
Isolated succinate-CoQ reductase deficiency (Orphanet:3208)
Leigh syndrome with leukodystrophy (Orphanet:255241)
Leigh syndrome with nephrotic syndrome (Orphanet:255249)
Pyruvate dehydrogenase lipoic acid synthetase deficiency (OMIM:614462)