Panhypogammaglobulinemia

Symptom Information:

Symptom ID: HPO:0003139
Synonyms:
Panypogammaglobulinemia [HPO:0003139]
Panhypogammaglobulinemia [OMIM:Panhypogammaglobulinemia]
Panypogammaglobulinemia [OMIM:Panypogammaglobulinemia]
Quality:
Cross references:
OMIM: "Panhypogammaglobulinemia" [OMIM:Panhypogammaglobulinemia]
OMIM: "Panypogammaglobulinemia" [OMIM:Panypogammaglobulinemia]
UMLS:C1849243 "Panypogammaglobulinemia" [HPO:0003139]
Is a (Direct Parents):
HPO         Decreased antibody level in blood
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of immune system physiology(HPO:0010978)
             Abnormality of humoral immunity(HPO:0005368)
                Abnormal immunoglobulin level(HPO:0010701)
                   Decreased antibody level in blood(HPO:0004313)
                      Panhypogammaglobulinemia(HPO:0003139)
          Abnormality of cellular immune system(HPO:0010987)
             Abnormality of leukocytes(HPO:0001881)
                Abnormality of lymphocytes(HPO:0004332)
                   Abnormality of B cells(HPO:0002846)
                      Abnormality of B cell physiology(HPO:0005372)
                         Abnormal immunoglobulin level(HPO:0010701)
                            Decreased antibody level in blood(HPO:0004313)
                               Panhypogammaglobulinemia(HPO:0003139)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of leukocytes(HPO:0001881)
             Abnormality of lymphocytes(HPO:0004332)
                Abnormality of B cells(HPO:0002846)
                   Abnormality of B cell physiology(HPO:0005372)
                      Abnormal immunoglobulin level(HPO:0010701)
                         Decreased antibody level in blood(HPO:0004313)
                            Panhypogammaglobulinemia(HPO:0003139)
MedDRA:
Database Frequency: 6 / 7739
Resource:

All diseases associated with this symptom:

Combined immunodeficiency due to ZAP70 deficiency (Orphanet:911)
Immunodeficiency by defective expression of HLA class 2 (Orphanet:572)
Severe combined immunodeficiency due to DCLRE1C deficiency (Orphanet:275)
Severe combined immunodeficiency due to complete RAG1/2 deficiency (Orphanet:331206)
Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia (Orphanet:632)
T-B+ severe combined immunodeficiency due to JAK3 deficiency (Orphanet:35078)