Progressive microcephaly

Symptom Information:

Symptom ID: HPO:0000253
Synonyms:
Microcephaly, postnatal, progressive [HPO:0000253]
Microcephaly, progressive [HPO:0000253]
Microcephaly, postnatal, progressive [OMIM:Microcephaly, postnatal, progressive]
Microcephaly, progressive [OMIM:Microcephaly, progressive]
Microcephaly, progressive (-3 to -5 SD) [OMIM:Microcephaly, progressive (-3 to -5 SD)]
Microcephaly, progressive (-3 to 6 SD) [OMIM:Microcephaly, progressive (-3 to 6 SD)]
Microcephaly, progressive (-3.5 to -10 SD) [OMIM:Microcephaly, progressive (-3.5 to -10 SD)]
Microcephaly, progressive (3 to 8 SD below the mean) [OMIM:Microcephaly, progressive (3 to 8 SD below the mean)]
Microcephaly, progressive (in 1 patient) [OMIM:Microcephaly, progressive (in 1 patient)]
Microcephaly, progressive (in 2 of 3 patients) [OMIM:Microcephaly, progressive (in 2 of 3 patients)]
Microcephaly, progressive (up to -7 SD) [OMIM:Microcephaly, progressive (up to -7 SD)]
Quality:
Cross references:
OMIM: "Microcephaly, postnatal, progressive" [OMIM:Microcephaly, postnatal, progressive]
OMIM: "Microcephaly, progressive" [OMIM:Microcephaly, progressive]
OMIM: "Microcephaly, progressive (-3 to -5 SD)" [OMIM:Microcephaly, progressive (-3 to -5 SD)]
OMIM: "Microcephaly, progressive (-3 to 6 SD)" [OMIM:Microcephaly, progressive (-3 to 6 SD)]
OMIM: "Microcephaly, progressive (-3.5 to -10 SD)" [OMIM:Microcephaly, progressive (-3.5 to -10 SD)]
OMIM: "Microcephaly, progressive (3 to 8 SD below the mean)" [OMIM:Microcephaly, progressive (3 to 8 SD below the mean)]
OMIM: "Microcephaly, progressive (in 1 patient)" [OMIM:Microcephaly, progressive (in 1 patient)]
OMIM: "Microcephaly, progressive (in 2 of 3 patients)" [OMIM:Microcephaly, progressive (in 2 of 3 patients)]
OMIM: "Microcephaly, progressive (up to -7 SD)" [OMIM:Microcephaly, progressive (up to -7 SD)]
Is a (Direct Parents):
HPO         Microcephaly
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of head or neck(HPO:0000152)
          Abnormality of the head(HPO:0000234)
             Abnormality of the skull(HPO:0000929)
                Abnormality of skull size(HPO:0000240)
                   Microcephaly(HPO:0000252)
                      Progressive microcephaly(HPO:0000253)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal axial skeleton morphology(HPO:0009121)
                Abnormality of the skull(HPO:0000929)
                   Abnormality of skull size(HPO:0000240)
                      Microcephaly(HPO:0000252)
                         Progressive microcephaly(HPO:0000253)
MedDRA:
Database Frequency: 37 / 7739
Resource:

All diseases associated with this symptom:

AICARDI-GOUTIERES SYNDROME 1 (OMIM:225750)
AICARDI-GOUTIERES SYNDROME 3 (OMIM:610329)
AICARDI-GOUTIERES SYNDROME 4 (OMIM:610333)
ASPARAGINE SYNTHETASE DEFICIENCY (OMIM:615574)
Amish lethal microcephaly (Orphanet:99742)
Atypical Rett syndrome (Orphanet:3095)
CEDNIK syndrome (Orphanet:66631)
CLN1 disease (Orphanet:228329)
COG1-CDG (Orphanet:263508)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 2 (OMIM:300672)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 5 (OMIM:613477)
Early myoclonic encephalopathy (Orphanet:1935)
GTP cyclohydrolase I deficiency (Orphanet:2102)
Gaucher disease type 2 (Orphanet:77260)
Infantile cerebellar-retinal degeneration (Orphanet:313850)
MICROCEPHALY, POSTNATAL PROGRESSIVE, WITH SEIZURES AND BRAIN ATROPHY (OMIM:613668)
MICROCEPHALY, PROGRESSIVE, WITH SEIZURES AND CEREBRAL AND CEREBELLARATROPHY (OMIM:615760)
MITOCHONDRIAL PYRUVATE CARRIER DEFICIENCY (OMIM:614741)
Mandibulofacial dysostosis-microcephaly syndrome (Orphanet:79113)
Microcephaly - seizures - developmental delay (Orphanet:228418)
Microcephaly-capillary malformation syndrome (Orphanet:294016)
PEHO syndrome (Orphanet:2836)
PEHO-like syndrome (Orphanet:99807)
PERIVENTRICULAR HETEROTOPIA WITH MICROCEPHALY, AUTOSOMAL RECESSIVE (OMIM:608097)
PONTOCEREBELLAR HYPOPLASIA, TYPE 1B (OMIM:614678)
PONTOCEREBELLAR HYPOPLASIA, TYPE 2A (OMIM:277470)
PONTOCEREBELLAR HYPOPLASIA, TYPE 2D (OMIM:613811)
Pontocerebellar hypoplasia type 2 (Orphanet:2524)
Pontocerebellar hypoplasia type 3 (Orphanet:97249)
Pontocerebellar hypoplasia type 6 (Orphanet:166073)
Pontocerebellar hypoplasia type 7 (Orphanet:284339)
Pontocerebellar hypoplasia, type 9 (OMIM:615809)
Pyridoxal phosphate-responsive seizures (Orphanet:79096)
RETT SYNDROME, CONGENITAL VARIANT (OMIM:613454)
Severe neonatal-onset encephalopathy with microcephaly (Orphanet:209370)
Wrinkly skin syndrome (Orphanet:2834)
X-linked intellectual deficit, Najm type (Orphanet:163937)