Pseudobulbar signs

Symptom Information:

Symptom ID: HPO:0002200
Synonyms:
Pseudobulbar symptoms [HPO:0002200]
Pseudobulbar affect [Orphanet:43090]
Mood swings (finding) [Orphanet:43090]
Pseudobulbar affect (finding) [Orphanet:43090]
Mood swings [Orphanet:43090]
Pseudobulbar signs [OMIM:Pseudobulbar signs]
Pseudobulbar symptoms [OMIM:Pseudobulbar symptoms]
Pseudobulbar signs/spasmodic laugh and cry [Orphanet:43090]
Mood altered [Orphanet:43090]
Mood swings [MedDRA:10027951]
Mood variable [MedDRA:10027951]
Mood altered [MedDRA:10027940]
Affect altered [MedDRA:10027940]
Altered mood [MedDRA:10027940]
Bad mood [MedDRA:10027940]
Mood alteration NOS [MedDRA:10027940]
Mood change [MedDRA:10027940]
Affect alteration [MedDRA:10027940]
Affect lability [MedDRA:10054196]
Emotional instability [MedDRA:10054196]
Emotional lability [MedDRA:10054196]
Instability emotional [MedDRA:10054196]
Labile affect [MedDRA:10054196]
Lability emotional [MedDRA:10054196]
Mental lability symptom [MedDRA:10054196]
Emotional incontinence [MedDRA:10054196]
Affective incontinence [MedDRA:10054196]
Pseudobulbar affect [MedDRA:10054196]
Emotional lability (2 patients) [OMIM:Emotional lability (2 patients)]
Emotional lability (in some) [OMIM:Emotional lability (in some)]
Emotional lability (variable) [OMIM:Emotional lability (variable)]
Pseudobulbar symptoms (uncontrolled laughter, weeping) [OMIM:Pseudobulbar symptoms (uncontrolled laughter, weeping)]
Quality:
Cross references:
HPO:0000712 "Emotional lability" [Orphanet:43090]
Orphanet:43090 "Pseudobulbar signs/spasmodic laugh and cry" [Orphanet:43090]
OMIM: "Pseudobulbar signs" [OMIM:Pseudobulbar signs]
OMIM: "Pseudobulbar symptoms" [OMIM:Pseudobulbar symptoms]
OMIM: "Emotional lability (2 patients)" [OMIM:Emotional lability (2 patients)]
OMIM: "Emotional lability (in some)" [OMIM:Emotional lability (in some)]
OMIM: "Emotional lability (variable)" [OMIM:Emotional lability (variable)]
OMIM: "Pseudobulbar symptoms (uncontrolled laughter, weeping)" [OMIM:Pseudobulbar symptoms (uncontrolled laughter, weeping)]
UMLS:C0085633 "Mood swings" [Orphanet:43090]
UMLS:C2316460 "Pseudobulbar affect" [Orphanet:43090]
Is a (Direct Parents):
HPO         Morphological abnormality of the central nervous system
Orphanet Functional anomalies of the nervous system
MedDRA Emotional and mood disturbances NEC
MedDRA Fluctuating mood symptoms
MedDRA Affect alterations NEC
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system morphology(HPO:0012639)
             Morphological abnormality of the central nervous system(HPO:0002011)
                Pseudobulbar signs(HPO:0002200)
MedDRA:
Database Frequency: 15 / 7739
Resource:

All diseases associated with this symptom:

AMYOTROPHIC LATERAL SCLEROSIS 2, JUVENILE (OMIM:205100)
ANGIOMATOSIS, DIFFUSE CORTICOMENINGEAL, OF DIVRY AND VAN BOGAERT (OMIM:206570)
Autosomal recessive spastic ataxia - optic atrophy - dysarthria (Orphanet:254343)
Autosomal recessive spastic paraplegia type 15 (Orphanet:100996)
Autosomal recessive spastic paraplegia type 20 (Orphanet:101000)
Autosomal recessive spastic paraplegia type 46 (Orphanet:320391)
CARASIL (Orphanet:199354)
COGNITIVE IMPAIRMENT WITH OR WITHOUT CEREBELLAR ATAXIA (OMIM:614306)
Juvenile primary lateral sclerosis (Orphanet:247604)
Neurodegeneration with brain iron accumulation due to C19orf12 mutation (Orphanet:289560)
SPASTIC PARAPLEGIA 50, AUTOSOMAL RECESSIVE (OMIM:612936)
Severe intellectual deficit and progressive spastic paraplegia (Orphanet:280763)
Sporadic Leigh syndrome (Orphanet:255199)
Wilson disease (Orphanet:905)
Wilson-Turner syndrome (Orphanet:3459)