Neonatal hypotonia

Symptom Information:

Symptom ID: HPO:0001319
Synonyms:
Hypotonia, in neonatal onset [HPO:0001319]
Hypotonia, neonatal [HPO:0001319]
Hypotonia, in neonatal onset [OMIM:Hypotonia, in neonatal onset]
Hypotonia, neonatal [OMIM:Hypotonia, neonatal]
Neonatal hypotonia [OMIM:Neonatal hypotonia]
Hypotonia, neonatal (> 90%) [OMIM:Hypotonia, neonatal (> 90%)]
Hypotonia neonatal [MedDRA:10021119]
Quality:
Cross references:
OMIM: "Hypotonia, in neonatal onset" [OMIM:Hypotonia, in neonatal onset]
OMIM: "Hypotonia, neonatal" [OMIM:Hypotonia, neonatal]
OMIM: "Neonatal hypotonia" [OMIM:Neonatal hypotonia]
OMIM: "Hypotonia, neonatal (> 90%)" [OMIM:Hypotonia, neonatal (> 90%)]
Is a (Direct Parents):
MedDRA Muscle tone abnormalities
HPO         Muscular hypotonia
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle physiology(HPO:0011804)
             Abnormal muscle tone(HPO:0003808)
                Muscular hypotonia(HPO:0001252)
                   Neonatal hypotonia(HPO:0001319)
MedDRA:
Musculoskeletal and connective tissue disorders(MedDRA:10028395)
    Muscle disorders(MedDRA:10028302)
       Muscle tone abnormalities(MedDRA:10028343)
          Neonatal hypotonia(HPO:0001319)
Database Frequency: 101 / 7739
Resource:

All diseases associated with this symptom:

14q11.2 microdeletion syndrome (Orphanet:261120)
1p36 deletion syndrome (Orphanet:1606)
2,4-@DIENOYL-CoA REDUCTASE 1, MITOCHONDRIAL (OMIM:222745)
3-methylglutaconic aciduria type 4 (Orphanet:67048)
ADENOSINE MONOPHOSPHATE DEAMINASE 1 (OMIM:102770)
AICA-ribosiduria (Orphanet:250977)
ALG11-CDG (Orphanet:280071)
Allan-Herndon-Dudley syndrome (Orphanet:59)
Autosomal recessive centronuclear myopathy (Orphanet:169186)
BONE MARROW FAILURE SYNDROME 2 (OMIM:615715)
Beta-ureidopropionase deficiency (Orphanet:65287)
Bethlem myopathy (Orphanet:610)
Bifunctional enzyme deficiency (Orphanet:300)
COENZYME Q10 DEFICIENCY, PRIMARY, 3 (OMIM:614652)
COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 19 (OMIM:615595)
Carnitine palmitoyl transferase II deficiency, neonatal form (Orphanet:228308)
Central core disease (Orphanet:597)
Cerebro-facio-thoracic dysplasia (Orphanet:1394)
Charcot-Marie-Tooth disease type 4E (Orphanet:99951)
Cohen syndrome (Orphanet:193)
Combined oxidative phosphorylation defect type 2 (Orphanet:254920)
Congenital fiber-type disproportion myopathy (Orphanet:2020)
Congenital lethal myopathy, Compton-North type (Orphanet:210163)
Congenital multicore myopathy with external ophthalmoplegia (Orphanet:98905)
Congenital muscular dystrophy due to phosphatidylcholine biosynthesis defect (Orphanet:280671)
Congenital muscular dystrophy with cerebellar involvement (Orphanet:370959)
Congenital muscular dystrophy with integrin alpha-7 deficiency (Orphanet:34520)
Congenital muscular dystrophy, Ullrich type (Orphanet:75840)
Congenital myopathy with excess of thin filaments (Orphanet:98904)
Corpus callosum agenesis - neuronopathy (Orphanet:1496)
D-glyceric aciduria (Orphanet:941)
Early myoclonic encephalopathy (Orphanet:1935)
Emery-Nelson syndrome (Orphanet:1927)
FG SYNDROME 2 (OMIM:300321)
FG SYNDROME 4 (OMIM:300422)
Fatal mitochondrial disease due to combined oxidative phosphorylation deficiency 3 (Orphanet:168566)
Fetal Gaucher disease (Orphanet:85212)
GRACILE syndrome (Orphanet:53693)
German syndrome (Orphanet:2077)
Hartsfield-Bixler-Demyer syndrome (Orphanet:2117)
Hereditary sensory and autonomic neuropathy type 6 (Orphanet:314381)
Hypotonia with lactic acidemia and hyperammonemia (Orphanet:137908)
Isolated succinate-CoQ reductase deficiency (Orphanet:3208)
Joubert syndrome 2 (OMIM:608091)
LEOPARD SYNDROME 3 (OMIM:613707)
Leigh syndrome with nephrotic syndrome (Orphanet:255249)
Lethal ataxia with deafness and optic atrophy (Orphanet:1187)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 18 (OMIM:615074)
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 42 (OMIM:615802)
MIDFACE HYPOPLASIA, OBESITY, DEVELOPMENTAL DELAY, AND NEONATAL HYPOTONIA (OMIM:608624)
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 7 (OMIM:615824)
MUSCULAR DYSTROPHY, CONGENITAL, MEROSIN-POSITIVE (OMIM:609456)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 12 (OMIM:615249)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH OR WITHOUTMENTAL RETARDATION), TYPE B, 5 (OMIM:606612)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (LIMB-GIRDLE), TYPE C, 12 (OMIM:616094)
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET (OMIM:614399)
MYOPATHY, AUTOPHAGIC VACUOLAR, INFANTILE-ONSET (OMIM:609500)
MYOPATHY, CONGENITAL, WITH FIBER-TYPE DISPROPORTION (OMIM:255310)
Micrencephaly - corpus callosum agenesis - abnormal genitalia (Orphanet:2508)
Moderate multiminicore disease with hand involvement (Orphanet:178145)
Monosomy 22q13 (Orphanet:48652)
Monosomy 5p (Orphanet:281)
Mucolipidosis type 2 (Orphanet:576)
Multiple sulfatase deficiency (Orphanet:585)
NEMALINE MYOPATHY 2 (OMIM:256030)
Nemaline myopathy (Orphanet:607)
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome (Orphanet:457185)
Neurologic Waardenburg-Shah syndrome (Orphanet:163746)
Non-progressive cerebellar ataxia with intellectual deficit (Orphanet:314647)
OPITZ-KAVEGGIA SYNDROME (OMIM:305450)
Oculocerebrorenal syndrome (Orphanet:534)
PEROXISOME BIOGENESIS DISORDER 1B (OMIM:601539)
PEROXISOME BIOGENESIS DISORDER 4B (OMIM:614863)
PEROXISOME BIOGENESIS DISORDER 5B (OMIM:614867)
PEROXISOME BIOGENESIS DISORDER 6B (OMIM:614871)
PEROXISOME BIOGENESIS DISORDER 7B (OMIM:614873)
PEROXISOME BIOGENESIS DISORDER 8B (OMIM:614877)
PLEOCONIAL MYOPATHY WITH SALT CRAVING (OMIM:262900)
PONTOCEREBELLAR HYPOPLASIA, TYPE 2E (OMIM:615851)
Paramyotonia congenita of Von Eulenburg (Orphanet:684)
Permanent neonatal diabetes mellitus - pancreatic and cerebellar agenesis (Orphanet:65288)
Peroxisomal acyl-CoA oxidase deficiency (Orphanet:2971)
Pitt-Hopkins-like syndrome 2 (OMIM:614325)
Polymicrogyria with optic nerve hypoplasia (Orphanet:250972)
Pontocerebellar hypoplasia type 3 (Orphanet:97249)
Pyruvate dehydrogenase E2 deficiency (Orphanet:79244)
Pyruvate dehydrogenase E3-binding protein deficiency (Orphanet:255182)
Pyruvate dehydrogenase deficiency (Orphanet:765)
RADICULONEUROPATHY, FATAL NEONATAL (OMIM:266250)
RETT SYNDROME, CONGENITAL VARIANT (OMIM:613454)
SCHAAF-YANG SYNDROME (OMIM:615547)
SOTOS SYNDROME 1 (OMIM:117550)
SPASTIC PARAPLEGIA 47, AUTOSOMAL RECESSIVE (OMIM:614066)
SPASTIC PARAPLEGIA 50, AUTOSOMAL RECESSIVE (OMIM:612936)
SPASTIC PARAPLEGIA 51, AUTOSOMAL RECESSIVE (OMIM:613744)
Severe intellectual deficit and progressive spastic paraplegia (Orphanet:280763)
Sotos syndrome (Orphanet:821)
X-linked creatine transporter deficiency (Orphanet:52503)
X-linked non progressive cerebellar ataxia (Orphanet:314978)
X-linked progressive cerebellar ataxia (Orphanet:1175)