Symptom Information: Sort according to HPO 

1
 (HPO:0000135) Hypogonadism 89 / 7739
2
 (HPO:0000252) Microcephaly 832 / 7739
3
 (HPO:0000668) Hypodontia 81 / 7739
4
 (HPO:0000670) Carious teeth 145 / 7739
5
 (HPO:0000771) Gynecomastia 53 / 7739
6
 (HPO:0000823) Delayed puberty 65 / 7739
7
 (HPO:0000953) Hyperpigmentation of the skin 75 / 7739
8
 (HPO:0000995) Melanocytic nevus 63 / 7739
9
 (HPO:0003758) Reduced subcutaneous adipose tissue 27 / 7739
10
 (HPO:0001193) Ulnar deviation of the hand or of fingers of the hand 17 / 7739
11
 (HPO:0001249) Intellectual disability 1089 / 7739
12
 (HPO:0001371) Flexion contracture 220 / 7739
13
 (HPO:0001596) Alopecia 162 / 7739
14
 (HPO:0002333) Motor deterioration 7 / 7739
15
 (HPO:0002751) Kyphoscoliosis 131 / 7739
16
 (HPO:0003202) Skeletal muscle atrophy 281 / 7739
17
 (HPO:0011734) Central adrenal insufficiency 2 / 7739
18
 (HPO:0006480) Premature loss of teeth 23 / 7739
19
 (OMIM) Hyperpigmentation in flexure areas 1 / 7739
20
 (OMIM) Alopecia, variable severity 1 / 7739
21
 (OMIM) Scalp biopsy shows absence of mature hair follicles 1 / 7739
22
 (OMIM) Mental retardation, moderate to severe 20 / 7739
23
 (OMIM) Motor deterioration in second decade 1 / 7739
24
 (OMIM) Upper motor neuron dysfunction 1 / 7739
25
 (OMIM) Lower motor neuron dysfunction 1 / 7739
26
 (OMIM) Brain MRI shows hypoplastic pituitary 1 / 7739
27
 (HPO:0000044) Hypogonadotrophic hypogonadism 56 / 7739
28
 (OMIM) Absent or delayed puberty 11 / 7739
29
 (HPO:0000007) Autosomal recessive inheritance 2538 / 7739
30
 (HPO:0002493) Upper motor neuron dysfunction 5 / 7739