1
|
(HPO:0001387)
|
Joint stiffness |
Very frequent [Orphanet]
|
|
|
|
322 / 7739
|
2
|
(HPO:0000572)
|
Visual loss |
Occasional [Orphanet]
|
|
|
|
272 / 7739
|
3
|
(HPO:0001903)
|
Anemia |
Occasional [Orphanet]
|
|
|
|
289 / 7739
|
4
|
(HPO:0200042)
|
Skin ulcer |
Occasional [Orphanet]
|
|
|
|
138 / 7739
|
5
|
(HPO:0002093)
|
Respiratory insufficiency |
Occasional [Orphanet]
|
|
|
|
410 / 7739
|
6
|
(HPO:0001970)
|
Tubulointerstitial nephritis |
Occasional [Orphanet]
|
|
|
|
27 / 7739
|
7
|
(HPO:0002716)
|
Lymphadenopathy |
Occasional [Orphanet]
|
|
|
|
129 / 7739
|
8
|
(HPO:0005059)
|
Arthralgia/arthritis |
Very frequent [Orphanet]
|
|
|
|
141 / 7739
|
9
|
(HPO:0100769)
|
Synovitis |
Very frequent [Orphanet]
|
|
|
|
86 / 7739
|
10
|
(HPO:0001410)
|
Decreased liver function |
Occasional [Orphanet]
|
|
|
|
59 / 7739
|
11
|
(HPO:0000613)
|
Photophobia |
Frequent [Orphanet]
|
|
|
|
158 / 7739
|
12
|
(HPO:0002616)
|
Aortic root dilatation |
Occasional [Orphanet]
|
|
|
|
27 / 7739
|
13
|
(HPO:0000610)
|
Abnormality of the choroid |
Occasional [Orphanet]
|
|
|
|
11 / 7739
|
14
|
(HPO:0000988)
|
Skin rash |
Very frequent [Orphanet]
|
|
|
|
98 / 7739
|
15
|
(HPO:0001085)
|
Papilledema |
|
|
|
|
31 / 7739
|
16
|
(HPO:0011227)
|
Elevated C-reactive protein level |
Very frequent [Orphanet]
|
|
|
|
55 / 7739
|
17
|
(HPO:0000518)
|
Cataract |
Frequent [Orphanet]
|
|
|
|
454 / 7739
|
18
|
(HPO:0000112)
|
Nephropathy |
Occasional [Orphanet]
|
|
|
|
92 / 7739
|
19
|
(HPO:0002092)
|
Pulmonary hypertension |
Occasional [Orphanet]
|
|
|
|
109 / 7739
|
20
|
(HPO:0010783)
|
Erythema |
Very frequent [Orphanet]
|
|
|
|
138 / 7739
|
21
|
(HPO:0000501)
|
Glaucoma |
Frequent [Orphanet]
|
|
|
|
180 / 7739
|
22
|
(HPO:0010628)
|
Facial palsy |
Occasional [Orphanet]
|
|
|
|
146 / 7739
|
23
|
(HPO:0000554)
|
Uveitis |
|
|
|
|
10 / 7739
|
24
|
(HPO:0008064)
|
Ichthyosis |
Occasional [Orphanet]
|
|
|
|
108 / 7739
|
25
|
(HPO:0000488)
|
Retinopathy |
Occasional [Orphanet]
|
|
|
|
75 / 7739
|
26
|
(HPO:0012089)
|
Arteritis |
Occasional [Orphanet]
|
|
|
|
40 / 7739
|
27
|
(HPO:0000822)
|
Hypertension |
Occasional [Orphanet]
|
|
|
|
224 / 7739
|
28
|
(HPO:0001697)
|
Abnormality of the pericardium |
Occasional [Orphanet]
|
|
|
|
52 / 7739
|
29
|
(HPO:0100490)
|
Camptodactyly of finger |
Frequent [Orphanet]
|
|
|
|
212 / 7739
|
30
|
(HPO:0000217)
|
Xerostomia |
Occasional [Orphanet]
|
|
|
|
35 / 7739
|
31
|
(HPO:0001744)
|
Splenomegaly |
Occasional [Orphanet]
|
|
|
|
337 / 7739
|
32
|
(HPO:0000083)
|
Renal insufficiency |
Occasional [Orphanet]
|
|
|
|
232 / 7739
|
33
|
(HPO:0010286)
|
Abnormality of the salivary glands |
Occasional [Orphanet]
|
|
|
|
7 / 7739
|
34
|
(HPO:0100654)
|
Retrobulbar optic neuritis |
Occasional [Orphanet]
|
|
|
|
5 / 7739
|
35
|
(HPO:0001945)
|
Fever |
Frequent [Orphanet]
|
|
|
|
218 / 7739
|
36
|
(HPO:0009726)
|
Renal neoplasm |
Occasional [Orphanet]
|
|
|
|
20 / 7739
|
37
|
(HPO:0000958)
|
Dry skin |
Frequent [Orphanet]
|
|
|
|
152 / 7739
|
38
|
(HPO:0000585)
|
Band keratopathy |
|
|
|
|
8 / 7739
|
39
|
(HPO:0000598)
|
Abnormality of the ear |
|
|
|
|
98 / 7739
|
40
|
(HPO:0000964)
|
Eczema |
|
|
|
|
81 / 7739
|
41
|
(HPO:0001101)
|
Iritis |
|
|
|
|
3 / 7739
|
42
|
(HPO:0001291)
|
Abnormality of the cranial nerves |
|
|
|
|
27 / 7739
|
43
|
(HPO:0001386)
|
Joint swelling |
|
|
|
|
7 / 7739
|
44
|
(HPO:0001933)
|
Subcutaneous hemorrhage |
Occasional [Orphanet]
|
|
|
|
50 / 7739
|
45
|
(HPO:0005830)
|
Flexion contracture of toe |
|
|
|
|
9 / 7739
|
46
|
(HPO:0007432)
|
Intermittent generalized erythematous papular rash |
|
|
|
|
1 / 7739
|
47
|
(HPO:0007813)
|
Nongranulomatous uveitis |
|
|
|
|
1 / 7739
|
48
|
(HPO:0011505)
|
Cystoid macular edema |
|
|
|
|
8 / 7739
|
49
|
(OMIM)
|
Multifocal choroiditis |
|
|
|
|
1 / 7739
|
50
|
(OMIM)
|
Granulomatous synovitis |
|
|
|
|
1 / 7739
|
51
|
(OMIM)
|
Granulomatous arthritis |
|
|
|
|
1 / 7739
|
52
|
(MedDRA:10042858)
|
Synovial cyst |
|
|
|
|
1 / 7739
|
53
|
(HPO:0001371)
|
Flexion contracture |
|
|
|
|
220 / 7739
|
54
|
(HPO:0100686)
|
Enthesitis |
|
|
|
|
5 / 7739
|
55
|
(HPO:0012385)
|
Camptodactyly |
|
|
|
|
113 / 7739
|
56
|
(OMIM)
|
Flexion contractures of the toes |
|
|
|
|
2 / 7739
|
57
|
(OMIM)
|
Granulomatous dermatitis |
|
|
|
|
3 / 7739
|
58
|
(OMIM)
|
Skin biopsy shows noncaseating granulomas |
|
|
|
|
1 / 7739
|
59
|
(OMIM)
|
Cysts over wrist and ankle joints |
|
|
|
|
1 / 7739
|
60
|
(HPO:0012795)
|
Abnormality of the optic disc |
Occasional [Orphanet]
|
|
|
|
187 / 7739
|
61
|
(HPO:0030350)
|
Erythematous papule |
Very frequent [Orphanet]
|
|
|
|
123 / 7739
|
62
|
(HPO:0100533)
|
Inflammatory abnormality of the eye |
Very frequent [Orphanet]
|
|
|
|
70 / 7739
|
63
|
(MedDRA:10025421)
|
Macule |
Very frequent [Orphanet]
|
|
|
|
55 / 7739
|
64
|
(HPO:0002011)
|
Morphological abnormality of the central nervous system |
Occasional [Orphanet]
|
|
|
|
5 / 7739
|
65
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|
66
|
(HPO:0001369)
|
Arthritis |
|
|
|
|
44 / 7739
|