Symptom Information: Sort according to HPO 

1
 (HPO:0000951) Abnormality of the skin Very frequent [IBIS] Very frequent [Orphanet] 20143182 IBIS 147 / 7739
2
 (HPO:0001009) Telangiectasia Very frequent [IBIS] 24142114 IBIS 46 / 7739
3
 (HPO:0002015) Dysphagia Very frequent [IBIS] Frequent [Orphanet] 24142114 IBIS 301 / 7739
4
 (HPO:0011838) Sclerodactyly Very frequent [IBIS] 24142114 IBIS 8 / 7739
5
 (OMIM) Raynaud syndrome Very frequent [IBIS] 24142114 IBIS 3 / 7739
6
 (HPO:0003761) Calcinosis Frequent [IBIS] 24142114 IBIS 12 / 7739
7
 (HPO:0002725) Systemic lupus erythematosus Occasional [IBIS] 11.1% (n=54) 2833902 IBIS 14 / 7739
8
 (HPO:0100614) Myositis Rare [IBIS] 5.6 % (n=54) 2833902 IBIS 21 / 7739
9
 (HPO:0001370) Rheumatoid arthritis Rare [IBIS] 5.6 % (n=54) 2833902 IBIS 12 / 7739
10
 (HPO:0002092) Pulmonary hypertension Occasional [Orphanet] 11669165 IBIS 109 / 7739
11
 (HPO:0200042) Skin ulcer Frequent [Orphanet] 16278765 IBIS 138 / 7739
12
 (HPO:0002093) Respiratory insufficiency Frequent [Orphanet] 16278765 IBIS 410 / 7739
13
 (HPO:0002592) Gastric ulcer Very frequent [Orphanet] 9732924 IBIS 39 / 7739
14
 (HPO:0100579) Mucosal telangiectasiae Frequent [Orphanet] 9732924 IBIS 10 / 7739
15
 (HPO:0100585) Telangiectasia of the skin Frequent [Orphanet] 16278765 IBIS 66 / 7739
16
 (HPO:0002960) Autoimmunity Very frequent [Orphanet] 16278765 IBIS 78 / 7739
17
 (HPO:0000969) Edema Very frequent [Orphanet] 16278765 IBIS 117 / 7739
18
 (HPO:0100324) Scleroderma 16278765 IBIS 6 / 7739
19
 (OMIM) Anticentromere and other antibodies 2833902 IBIS 1 / 7739
20
 (MedDRA:10061156) Finger deformity 24142114 IBIS 5 / 7739
21
 (MedDRA:10042953) Systemic sclerosis 24142114 IBIS 1 / 7739
22
 (HPO:0002633) Vasculitis 22387650 IBIS 12 / 7739
23
 (HPO:0040078) Axonal degeneration 22387650 IBIS 10 / 7739
24
 (HPO:0007141) Sensorimotor neuropathy 22387650 IBIS 27 / 7739
25
 (HPO:0001337) Tremor 22387650 IBIS 200 / 7739
26
 (HPO:0001251) Ataxia 22387650 IBIS 413 / 7739
27
 (HPO:0001873) Thrombocytopenia 21982887 IBIS 224 / 7739
28
 (MedDRA:10052178) Lymphocytic lymphoma 21982887 IBIS 2 / 7739
29
 (HPO:0000980) Pallor 20143182 IBIS 52 / 7739
30
 (HPO:0000961) Cyanosis 20143182 IBIS 60 / 7739
31
 (HPO:0010783) Erythema 20143182 IBIS 138 / 7739
32
 (HPO:0002829) Arthralgia 24142114 IBIS 79 / 7739
33
 (HPO:0001324) Muscle weakness 24142114 IBIS 859 / 7739
34
 (HPO:0011675) Arrhythmia 24142114 IBIS 226 / 7739
35
 (HPO:0002613) Biliary cirrhosis 24142114 IBIS 11 / 7739
36
 (MedDRA:10007697) Carpal tunnel syndrome 24142114 IBIS 16 / 7739
37
 (HPO:0012181) Entrapment neuropathy 24142114 IBIS 1 / 7739
38
 (OMIM) Increased risk for cancer 24142114 IBIS 3 / 7739
39
 (HPO:0001072) Thickened skin 24142114 IBIS 87 / 7739
40
 (MedDRA:10068057) Dependent rubor 24142114 IBIS 1 / 7739
41
 (HPO:0012531) Pain 24142114 IBIS 9 / 7739
42
 (HPO:0003401) Paresthesia 24142114 IBIS 42 / 7739
43
 (HPO:0001637) Abnormality of the myocardium 27169738 IBIS 76 / 7739
44
 (HPO:0001697) Abnormality of the pericardium 27169738 IBIS 52 / 7739
45
 (HPO:0004930) Abnormality of the pulmonary vasculature 27169738 IBIS 3 / 7739
46
 (HPO:0000988) Skin rash 16278765 IBIS 98 / 7739
47
 (MedDRA:10016642) Fibrosis 16278765 IBIS 9 / 7739
48
 (HPO:0100771) Hypoperistalsis 16278765 IBIS 5 / 7739
49
 (HPO:0100633) Esophagitis 16278765 IBIS 7 / 7739
50
 (HPO:0002020) Gastroesophageal reflux 16278765 IBIS 101 / 7739
51
 (OMIM) Edema, nonpitting 16278765 IBIS 3 / 7739
52
 (HPO:0002239) Gastrointestinal hemorrhage 9732924 IBIS 97 / 7739
53
 (HPO:0005263) Gastritis 9732924 IBIS 9 / 7739
54
 (HPO:0002027) Abdominal pain 26607041 IBIS 184 / 7739
55
 (HPO:0030151) Cholangitis 26607041 IBIS 10 / 7739
56
 (HPO:0012378) Fatigue 26607041 IBIS 50 / 7739
57
 (HPO:0004398) Peptic ulcer 9732924 IBIS 7 / 7739