Symptom Information: Sort according to HPO 

1
(HPO:0012120) Methylmalonic aciduria Very Frequent [IBIS] 27519416 IBIS 20 / 7739
2
(HPO:0001508) Failure to thrive Frequent [IBIS] 27519416 IBIS 454 / 7739
3
(HPO:0001254) Lethargy Frequent [IBIS] 27519416 IBIS 104 / 7739
4
(HPO:0001970) Tubulointerstitial nephritis Frequent [IBIS] 27519416 IBIS 27 / 7739
5
(HPO:0005979) Metabolic ketoacidosis Frequent [IBIS] 27519416 IBIS 4 / 7739
6
(OMIM) Neonatal or infantile metabolic ketoacidosis Frequent [IBIS] 27519416 IBIS 3 / 7739
7
(HPO:0012758) Neurodevelopmental delay Frequent [Orphanet], Frequent [IBIS] 27519416 IBIS 949 / 7739
8
(HPO:0001993) Ketoacidosis Frequent [IBIS] 27519416 IBIS 17 / 7739
9
(HPO:0012622) Chronic kidney disease Frequent [IBIS] 27519416 IBIS 32 / 7739
10
(HPO:0001947) Renal tubular acidosis Frequent [IBIS] 27519416 IBIS 21 / 7739
11
(HPO:0001332) Dystonia Occasional [Orphanet] 197 / 7739
12
(HPO:0100806) Sepsis Occasional [Orphanet] 48 / 7739
13
(HPO:0001874) Abnormality of neutrophils Occasional [Orphanet] 47 / 7739
14
(HPO:0001252) Muscular hypotonia Frequent [Orphanet] 990 / 7739
15
(HPO:0001324) Muscle weakness 859 / 7739
16
(HPO:0001903) Anemia Occasional [Orphanet] 289 / 7739
17
(HPO:0002093) Respiratory insufficiency Frequent [Orphanet] 410 / 7739
18
(HPO:0004374) Hemiplegia/hemiparesis Occasional [Orphanet] 158 / 7739
19
(HPO:0001259) Coma 27519416 IBIS 65 / 7739
20
(HPO:0002240) Hepatomegaly Frequent [Orphanet] 467 / 7739
21
(HPO:0000083) Renal insufficiency Occasional [Orphanet] 232 / 7739
22
(HPO:0000124) Renal tubular dysfunction Occasional [Orphanet] 27519416 IBIS 46 / 7739
23
(HPO:0002017) Nausea and vomiting Very frequent [Orphanet] 134 / 7739
24
(HPO:0001873) Thrombocytopenia Frequent [Orphanet] 224 / 7739
25
(HPO:0001733) Pancreatitis Occasional [Orphanet] 46 / 7739
26
(HPO:0001987) Hyperammonemia Occasional [Orphanet] 50 / 7739
27
(HPO:0001263) Global developmental delay 853 / 7739
28
(HPO:0001638) Cardiomyopathy 192 / 7739
29
(HPO:0001882) Leukopenia 51 / 7739
30
(HPO:0001944) Dehydration 59 / 7739
31
(HPO:0002154) Hyperglycinemia 12 / 7739
32
(HPO:0003774) Stage 5 chronic kidney disease 78 / 7739
33
(HPO:0004372) Reduced consciousness/confusion Very frequent [Orphanet] 73 / 7739
34
(HPO:0011695) Cerebellar hemorrhage 6 / 7739
35
(OMIM) Recurrent episodes of vomiting 3 / 7739
36
(HPO:0008947) Infantile muscular hypotonia 482 / 7739
37
(HPO:0010547) Muscle flaccidity 466 / 7739
38
(OMIM) Severe involvement of globus pallidus 3 / 7739
39
(OMIM) Delay in myelination 3 / 7739
40
(OMIM) Ischemic stroke in the basal ganglia (rare) 4 / 7739
41
(OMIM) Normal serum cobalamin 7 / 7739
42
(OMIM) Methylmalonyl-CoA mutase deficiency 3 / 7739
43
(OMIM) Low plasma free and total carnitine 3 / 7739
44
(HPO:0004325) Decreased body weight Very frequent [Orphanet] 492 / 7739
45
(HPO:0012795) Abnormality of the optic disc Occasional [Orphanet] 187 / 7739
46
(HPO:0004305) Involuntary movements Occasional [Orphanet] 50 / 7739