Symptom Information: Sort according to HPO 

1
 (HPO:0011020) Abnormality of mucopolysaccharide metabolism Very frequent [IBIS] 18038146 IBIS 17 / 7739
2
 (HPO:0010741) Edema of the lower limbs 26633932 IBIS 34 / 7739
3
 (HPO:0001538) Protuberant abdomen 26633932 IBIS 36 / 7739
4
 (HPO:0002094) Dyspnea 26633932 IBIS 132 / 7739
5
 (HPO:0000271) Abnormality of the face 26633932 IBIS 108 / 7739
6
 (HPO:0011220) Prominent forehead 26633932 IBIS 137 / 7739
7
 (HPO:0000520) Proptosis 26633932 IBIS 192 / 7739
8
 (HPO:0430028) Hyperplasia of the maxilla 26633932 IBIS 1 / 7739
9
 (HPO:0000303) Mandibular prognathia 26633932 IBIS 179 / 7739
10
 (HPO:0001072) Thickened skin 26633932 IBIS 87 / 7739
11
 (MedDRA:10041235) Snoring 26633932 IBIS 8 / 7739
12
 (HPO:0000365) Hearing impairment 26633932; 11015461; 9611068; 12572848 IBIS 539 / 7739
13
 (HPO:0002376) Developmental regression 26633932; 18245410; 9611068 IBIS 74 / 7739
14
 (HPO:0000256) Macrocephaly 26633932 IBIS 298 / 7739
15
 (HPO:0002007) Frontal bossing 26633932 IBIS 366 / 7739
16
 (HPO:0000929) Abnormality of the skull 26633932 IBIS 53 / 7739
17
 (HPO:0000369) Low-set ears 26633932 IBIS 372 / 7739
18
 (HPO:0005280) Depressed nasal bridge 26633932 IBIS 381 / 7739
19
 (HPO:0000463) Anteverted nares 26633932 IBIS 305 / 7739
20
 (HPO:0010808) Protruding tongue 26633932 IBIS 28 / 7739
21
 (HPO:0000470) Short neck 26633932 IBIS 345 / 7739
22
 (HPO:0011927) Short digit 26633932 IBIS 17 / 7739
23
 (HPO:0011355) Localized skin lesion 26633932 IBIS 3 / 7739
24
 (HPO:0005348) Inspiratory stridor 26633932 IBIS 8 / 7739
25
 (HPO:0000961) Cyanosis 26633932 IBIS 60 / 7739
26
 (MedDRA:10011704) Cyanosis central 26633932 IBIS 1 / 7739
27
 (HPO:0040168) Focal seizures, afebril 26633932 IBIS 6 / 7739
28
 (HPO:0000969) Edema 26633932 IBIS 117 / 7739
29
 (HPO:0008897) Postnatal growth retardation 26633932 IBIS 113 / 7739
30
 (HPO:0001387) Joint stiffness 26633932; 9611068; 12572848 IBIS 322 / 7739
31
 (HPO:0001649) Tachycardia 26633932 IBIS 53 / 7739
32
 (HPO:0030148) Heart murmur 26633932 IBIS 29 / 7739
33
 (HPO:0002789) Tachypnea 26633932 IBIS 48 / 7739
34
 (HPO:0001537) Umbilical hernia 26633932; 12572848 IBIS 206 / 7739
35
 (HPO:0001433) Hepatosplenomegaly 26633932; 11015461; 9611068; 12572848; 15797184 IBIS 78 / 7739
36
 (HPO:0001541) Ascites 26633932 IBIS 94 / 7739
37
 (HPO:0004823) Anisopoikilocytosis 26633932 IBIS 4 / 7739
38
 (HPO:0005518) Erythrocyte macrocytosis 26633932 IBIS 13 / 7739
39
 (HPO:0001931) Hypochromic anemia 26633932 IBIS 5 / 7739
40
 (HPO:0002680) J-shaped sella turcica 26633932 IBIS 15 / 7739
41
 (HPO:0004568) Beaking of vertebral bodies 26633932 IBIS 19 / 7739
42
 (HPO:0002945) Intervertebral space narrowing 26633932 IBIS 7 / 7739
43
 (HPO:0001634) Mitral valve prolapse 26633932 IBIS 69 / 7739
44
 (HPO:0001653) Mitral regurgitation 26633932 IBIS 64 / 7739
45
 (HPO:0001698) Pericardial effusion 26633932 IBIS 20 / 7739
46
 (HPO:0002092) Pulmonary hypertension 26633932 IBIS 109 / 7739
47
 (HPO:0002159) Heparan sulfate excretion in urine 26633932; 11015461; 9611068 IBIS 12 / 7739
48
 (HPO:0001263) Global developmental delay 18245410; 9611068; 15797184 IBIS 853 / 7739
49
 (HPO:0001334) Communicating hydrocephalus 18245410 IBIS 32 / 7739
50
 (HPO:0002516) Increased intracranial pressure 18245410 IBIS 47 / 7739
51
 (HPO:0012795) Abnormality of the optic disc 18245410 IBIS 187 / 7739
52
 (HPO:0000648) Optic atrophy 18245410 IBIS 238 / 7739
53
 (HPO:0001250) Seizures 18245410 IBIS 1245 / 7739
54
 (HPO:0006536) Obstructive lung disease 18245410 IBIS 7 / 7739
55
 (HPO:0001626) Abnormality of the cardiovascular system 18245410; 15797184 IBIS 73 / 7739
56
 (HPO:0000752) Hyperactivity 18245410; 9611068 IBIS 140 / 7739
57
 (HPO:0000708) Behavioral abnormality 18245410; 15797184 IBIS 212 / 7739
58
 (HPO:0000718) Aggressive behavior 18245410 IBIS 109 / 7739
59
 (HPO:0008301) Dermatan sulfate excretion in urine 11015461; 9611068 IBIS 8 / 7739
60
 (HPO:0000280) Coarse facial features 11015461; 9611068; 15797184 IBIS 189 / 7739
61
 (HPO:0005619) Thoracolumbar kyphosis 11015461 IBIS 8 / 7739
62
 (HPO:0001376) Limitation of joint mobility 11015461 IBIS 27 / 7739
63
 (HPO:0001249) Intellectual disability 11015461; 12572848 IBIS 1089 / 7739
64
 (HPO:0005176) Dysplastic aortic valve 11015461 IBIS 2 / 7739
65
 (HPO:0002240) Hepatomegaly 9611068 IBIS 467 / 7739
66
 (HPO:0000924) Abnormality of the skeletal system 9611068; 12572848 IBIS 114 / 7739
67
 (HPO:0000158) Macroglossia 9611068; 15797184 IBIS 119 / 7739
68
 (HPO:0000023) Inguinal hernia 12572848 IBIS 181 / 7739
69
 (HPO:0002788) Recurrent upper respiratory tract infections 12572848 IBIS 31 / 7739
70
 (HPO:0002751) Kyphoscoliosis 12572848 IBIS 131 / 7739
71
 (HPO:0004322) Short stature 12572848; 15797184 IBIS 1232 / 7739
72
 (HPO:0005684) Distal arthrogryposis 15797184 IBIS 31 / 7739
73
 (HPO:0002808) Kyphosis 15797184 IBIS 289 / 7739
74
 (HPO:0001730) Progressive hearing impairment 15797184 IBIS 29 / 7739
75
 (HPO:0000403) Recurrent otitis media 15797184 IBIS 61 / 7739
76
 (HPO:0100785) Insomnia 15797184 IBIS 18 / 7739
77
 (MedDRA:10007697) Carpal tunnel syndrome 15797184 IBIS 16 / 7739
78
 (MedDRA:10001229) Adenoidal hypertrophy 15797184 IBIS 3 / 7739
79
 (HPO:3000033) Abnormality of nasopharyngeal adenoids 15797184 IBIS 4 / 7739
80
 (HPO:0003541) Urinary glycosaminoglycan excretion 15797184 IBIS 6 / 7739
81
 (HPO:0000707) Abnormality of the nervous system 18245410 IBIS 61 / 7739