MALIGNANT HYPERTHERMIA, SUSCEPTIBILITY TO, 3

General Information (adopted from Orphanet):

Synonyms, Signs: MHS3
Number of Symptoms 15
OrphanetNr:
OMIM Id: 154276
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Heterogeneous
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
 (HPO:0001276) Hypertonia 317 / 7739
2
 (HPO:0001945) Fever 218 / 7739
3
 (HPO:0002047) Malignant hyperthermia 20 / 7739
4
 (HPO:0002153) Hyperkalemia 25 / 7739
5
 (HPO:0003128) Lactic acidosis 116 / 7739
6
 (HPO:0002905) Hyperphosphatemia 18 / 7739
7
 (HPO:0003236) Elevated serum creatine phosphokinase 214 / 7739
8
 (HPO:0003558) Viral infection-induced rhabdomyolysis 2 / 7739
9
 (HPO:0011439) Anesthetic-induced rhabdomylosis 2 / 7739
10
 (HPO:0011440) Alcohol-induced rhabdomyolysis 2 / 7739
11
 (HPO:0003198) Myopathy 151 / 7739
12
 (HPO:0009045) Exercise-induced rhabdomyolysis 3 / 7739
13
 (HPO:0001425) Heterogeneous 132 / 7739
14
 (OMIM) Rhabdomyolysis may follow severe exercise in hot conditions, neuroleptic drugs, alcohol, or infections 2 / 7739
15
 (OMIM) Elevated blood CPK, phosphate and potassium 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: