Decreased methionine synthase activity

Symptom Information:

Symptom ID: HPO:0003524
Synonyms:
Decreased activity of methionine synthase [HPO:0003524]
Decreased methionine synthase (MTR, 156570) activity [HPO:0003524]
Methionine synthase deficiency [HPO:0003524]
Methionine synthetase activity decreased [HPO:0003524]
Decreased activity of methionine synthase (MTR, 156570) [OMIM:Decreased activity of methionine synthase (MTR, 156570)]
Decreased methionine synthase (MTR, 156570) activity [OMIM:Decreased methionine synthase (MTR, 156570) activity]
Quality:
Cross references:
OMIM: "Decreased activity of methionine synthase (MTR, 156570)" [OMIM:Decreased activity of methionine synthase (MTR, 156570)]
OMIM: "Decreased methionine synthase (MTR, 156570) activity" [OMIM:Decreased methionine synthase (MTR, 156570) activity]
Is a (Direct Parents):
HPO         Abnormality of methionine metabolism
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of metabolism/homeostasis(HPO:0001939)
          Abnormality of carboxylic acid metabolism(HPO:0004354)
             Abnormality of amino acid metabolism(HPO:0004337)
                Abnormality of sulfur amino acid metabolism(HPO:0004339)
                   Abnormality of methionine metabolism(HPO:0010901)
                      Decreased methionine synthase activity(HPO:0003524)
                Abnormality of aspartate family amino acid metabolism(HPO:0010899)
                   Abnormality of methionine metabolism(HPO:0010901)
                      Decreased methionine synthase activity(HPO:0003524)
MedDRA:
Database Frequency: 9 / 7739
Resource:

All diseases associated with this symptom:

Methylcobalamin deficiency type cblDv1 (Orphanet:308380)
Methylcobalamin deficiency type cblE (Orphanet:2169)
Methylcobalamin deficiency type cblG (Orphanet:2170)
Methylmalonic acidemia with homocystinuria (Orphanet:26)
Methylmalonic acidemia with homocystinuria, type cblC (Orphanet:79282)
Methylmalonic acidemia with homocystinuria, type cblD (Orphanet:79283)
Methylmalonic acidemia with homocystinuria, type cblF (Orphanet:79284)
Methylmalonic acidemia with homocystinuria, type cblJ (Orphanet:369955)
Vitamin B12-responsive methylmalonic acidemia, type cblDv2 (Orphanet:308442)