Chromosomal breakage induced by crosslinking agents

Symptom Information:

Symptom ID: HPO:0003221
Synonyms:
Chromosomal breakage induced by diepoxybutane [HPO:0003221]
Chromosomal breakage induced by mitomycin C [HPO:0003221]
Quality:
Cross references:
Is a (Direct Parents):
HPO         Abnormality of chromosome stability
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of metabolism/homeostasis(HPO:0001939)
          Abnormality of cell physiology(HPO:0011017)
             Abnormality of chromosome stability(HPO:0003220)
                Chromosomal breakage induced by crosslinking agents(HPO:0003221)
MedDRA:
Database Frequency: 8 / 7739
Resource:

All diseases associated with this symptom:

FANCONI ANEMIA, COMPLEMENTATION GROUP A (OMIM:227650)
FANCONI ANEMIA, COMPLEMENTATION GROUP D2 (OMIM:227646)
FANCONI ANEMIA, COMPLEMENTATION GROUP E (OMIM:600901)
FANCONI ANEMIA, COMPLEMENTATION GROUP I (OMIM:609053)
FANCONI ANEMIA, COMPLEMENTATION GROUP J (OMIM:609054)
FANCONI ANEMIA, COMPLEMENTATION GROUP N (OMIM:610832)
Fanconi anemia (Orphanet:84)
Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations (Orphanet:319462)