Ragged-red muscle fibers

Symptom Information:

Symptom ID: HPO:0003200
Synonyms:
Mitochondrial proliferation in muscle tissue [HPO:0003200]
Ragged red muscle fibers [HPO:0003200]
Ragged-red fibers [HPO:0003200]
Ragged-red fibers [OMIM:Ragged-red fibers]
Ragged red fibers [OMIM:Ragged red fibers]
Red-ragged fibers (2p21del) [OMIM:Red-ragged fibers (2p21del)]
Ragged red fibers seen on muscle biopsy [OMIM, bb]
Quality:
Cross references:
OMIM: "Ragged-red fibers" [OMIM:Ragged-red fibers]
OMIM: "Ragged red fibers" [OMIM:Ragged red fibers]
OMIM: "Red-ragged fibers (2p21del)" [OMIM:Red-ragged fibers (2p21del)]
Is a (Direct Parents):
HPO         Abnormality of muscle fibers
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle morphology(HPO:0011805)
             Abnormality of muscle fibers(HPO:0004303)
                Ragged-red muscle fibers(HPO:0003200)
MedDRA:
Database Frequency: 37 / 7739
Resource:

All diseases associated with this symptom:

2p21 microdeletion syndrome (Orphanet:163693)
Adult-onset multiple mitochondrial DNA deletion syndrome due to DGUOK deficiency (Orphanet:329314)
Atypical hypotonia - cystinuria syndrome (Orphanet:238523)
Autosomal dominant limb-girdle muscular dystrophy type 1H (Orphanet:238755)
Autosomal dominant optic atrophy and congenital deafness (Orphanet:3212)
Autosomal dominant progressive external ophthalmoplegia (Orphanet:254892)
Autosomal recessive progressive external ophthalmoplegia (Orphanet:254886)
Autosomal recessive spastic paraplegia type 7 (Orphanet:99013)
COENZYME Q10 DEFICIENCY, PRIMARY, 1 (OMIM:607426)
Cardiomyopathy, familial hypertrophic, 8 (OMIM:608751)
Congenital cataract-hypertrophic cardiomyopathy-mitochondrial myopathy syndrome (Orphanet:1369)
Fatal infantile lactic acidosis with methylmalonic aciduria (Orphanet:17)
Hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial DNA mutation (Orphanet:324525)
Hypotonia - cystinuria syndrome (Orphanet:163690)
Isolated CoQ-cytochrome C reductase deficiency (Orphanet:1460)
Isolated succinate-CoQ reductase deficiency (Orphanet:3208)
Kearns-Sayre syndrome (Orphanet:480)
Laing distal myopathy (Orphanet:59135)
Leber plus disease (Orphanet:99718)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
MELAS (Orphanet:550)
MERRF (Orphanet:551)
MYASTHENIC SYNDROME, CONGENITAL, 14 (OMIM:616228)
MYOGLOBINURIA, RECURRENT (OMIM:550500)
Mitochondrial DNA deletion syndrome with progressive myopathy (Orphanet:352470)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy (Orphanet:255235)
Mitochondrial DNA depletion syndrome, myopathic form (Orphanet:254875)
Mitochondrial myopathy with reversible cytochrome C oxidase deficiency (Orphanet:254864)
Mitochondrial neurogastrointestinal encephalomyopathy (Orphanet:298)
Myopathy and diabetes mellitus (Orphanet:2596)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 2 (OMIM:609283)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 3 (OMIM:609286)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 5 (OMIM:613077)
Ramsay-Hunt syndrome (Orphanet:3020)
STRIATONIGRAL DEGENERATION, INFANTILE, MITOCHONDRIAL (OMIM:500003)
Severe X-linked mitochondrial encephalomyopathy (Orphanet:238329)
Spinocerebellar ataxia with epilepsy (Orphanet:254881)