Degeneration of anterior horn cells

Symptom Information:

Symptom ID: HPO:0002398
Synonyms:
Anterior horn cell loss [HPO:0002398]
Degeneration of alpha-motor neurons in anterior horn cells of the spinal cord [HPO:0002398]
Degeneration of spinal cord anterior horn cells [HPO:0002398]
Loss of spinal cord anterior horn cells [HPO:0002398]
Progressive loss of anterior horn cells [HPO:0002398]
Spinal cord anterior horn cell degeneration [HPO:0002398]
Anterior horn cell loss [OMIM:Anterior horn cell loss]
Degeneration of alpha-motor neurons in anterior horn cells of the spinal cord [OMIM:Degeneration of alpha-motor neurons in anterior horn cells of the spinal cord]
Degeneration of anterior horn cells [OMIM:Degeneration of anterior horn cells]
Degeneration of spinal cord anterior horn cells [OMIM:Degeneration of spinal cord anterior horn cells]
Loss of spinal cord anterior horn cells [OMIM:Loss of spinal cord anterior horn cells]
Spinal cord anterior horn cell degeneration [OMIM:Spinal cord anterior horn cell degeneration]
Quality:
Cross references:
OMIM: "Anterior horn cell loss" [OMIM:Anterior horn cell loss]
OMIM: "Degeneration of alpha-motor neurons in anterior horn cells of the spinal cord" [OMIM:Degeneration of alpha-motor neurons in anterior horn cells of the spinal cord]
OMIM: "Degeneration of anterior horn cells" [OMIM:Degeneration of anterior horn cells]
OMIM: "Degeneration of spinal cord anterior horn cells" [OMIM:Degeneration of spinal cord anterior horn cells]
OMIM: "Loss of spinal cord anterior horn cells" [OMIM:Loss of spinal cord anterior horn cells]
OMIM: "Spinal cord anterior horn cell degeneration" [OMIM:Spinal cord anterior horn cell degeneration]
Is a (Direct Parents):
HPO         Abnormal upper motor neuron morphology
HPO         Motor neuron atrophy
HPO         Abnormal anterior horn cell morphology
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system morphology(HPO:0012639)
             Abnormal peripheral nervous system morphology(HPO:0000759)
                Abnormal anterior horn cell morphology(HPO:0006802)
                   Degeneration of anterior horn cells(HPO:0002398)
             Morphological abnormality of the central nervous system(HPO:0002011)
                Abnormal motor neuron morphology(HPO:0002450)
                   Abnormal upper motor neuron morphology(HPO:0002127)
                      Degeneration of anterior horn cells(HPO:0002398)
                   Motor neuron atrophy(HPO:0007373)
                      Degeneration of anterior horn cells(HPO:0002398)
MedDRA:
Database Frequency: 14 / 7739
Resource:

All diseases associated with this symptom:

Amyotrophic lateral sclerosis (Orphanet:803)
Amyotrophic lateral sclerosis type 4 (Orphanet:357043)
CHARCOT-MARIE-TOOTH DISEASE WITH PTOSIS AND PARKINSONISM (OMIM:118301)
Hereditary motor and sensory neuropathy, Okinawa type (Orphanet:90117)
Hereditary myoclonus - progressive distal muscular atrophy (Orphanet:2590)
MOTOR NEURON DISEASE WITH DEMENTIA AND OPHTHALMOPLEGIA (OMIM:600333)
PONTOCEREBELLAR HYPOPLASIA, TYPE 1A (OMIM:607596)
Pontocerebellar hypoplasia type 1 (Orphanet:2254)
Proximal spinal muscular atrophy type 2 (Orphanet:83418)
Proximal spinal muscular atrophy type 3 (Orphanet:83419)
Proximal spinal muscular atrophy type 4 (Orphanet:83420)
SPINAL MUSCULAR ATROPHY, DISTAL, AUTOSOMAL RECESSIVE, 1 (OMIM:604320)
Spinal muscular atrophy with respiratory distress (Orphanet:98920)
X-linked distal arthrogryposis multiplex congenita (Orphanet:1145)