Fragile nails

Symptom Information:

Symptom ID: HPO:0001808
Synonyms:
Brittle nails [HPO:0001808]
Brittle hair [Orphanet:24680]
Trichorrhexis (disorder) [Orphanet:24680]
Bamboo hair (disorder) [Orphanet:24680]
Brittle hair (disorder) [Orphanet:24680]
Trichorrhexis [Orphanet:24680]
Brittle nails [OMIM:Brittle nails]
Fragile nails [OMIM:Fragile nails]
Brittle hair/distrix/trichorrhexis [Orphanet:24680]
Trichorrhexis [MedDRA:10044625]
Split ends [MedDRA:10044625]
Trichorrhexis nodosa [MedDRA:10044625]
Hair breakage [MedDRA:10044625]
Brittle hair (in some patients) [OMIM:Brittle hair (in some patients)]
Quality:
Cross references:
HPO:0002299 "Brittle hair" [Orphanet:24680]
HPO:0004779 "Brittle scalp hair" [Orphanet:24680]
HPO:0009886 "Trichorrhexis nodosa" [Orphanet:24680]
Orphanet:24680 "Brittle hair/distrix/trichorrhexis" [Orphanet:24680]
OMIM: "Brittle nails" [OMIM:Brittle nails]
OMIM: "Fragile nails" [OMIM:Fragile nails]
OMIM: "Brittle hair (in some patients)" [OMIM:Brittle hair (in some patients)]
UMLS:C0702163 "Trichorrhexis" [Orphanet:24680]
UMLS:C0263490 "Brittle hair" [Orphanet:24680]
Is a (Direct Parents):
MedDRA Pilar disorders NEC
Orphanet Abnormality of hair texture
HPO         Abnormality of the nail
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of skin adnexa(HPO:0011138)
             Abnormality of the nail(HPO:0001597)
                Fragile nails(HPO:0001808)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Skin appendage conditions(MedDRA:10040798)
       Pilar disorders NEC(MedDRA:10035035)
          Fragile nails(HPO:0001808)
Database Frequency: 21 / 7739
Resource:

All diseases associated with this symptom:

Argininosuccinic aciduria (Orphanet:23)
Beckwith-Wiedemann syndrome due to NSD1 mutation (Orphanet:238613)
Cardiomyopathy, dilated, with woolly hair, keratoderma, and toothagenesis (OMIM:615821)
Costello syndrome (Orphanet:3071)
Craniofrontonasal dysplasia (Orphanet:1520)
ECTODERMAL DYSPLASIA 4, HAIR/NAIL TYPE (OMIM:602032)
Generalized junctional epidermolysis bullosa, non-Herlitz type (Orphanet:79402)
ICHTHYOSIFORM ERYTHRODERMA, CORNEAL INVOLVEMENT, AND DEAFNESS (OMIM:242150)
Junctional epidermolysis bullosa inversa (Orphanet:79405)
Junctional epidermolysis bullosa, non-Herlitz type (Orphanet:89840)
Langer-Giedion syndrome (Orphanet:502)
Localized junctional epidermolysis bullosa, non-Herlitz type (Orphanet:251393)
Mal de Meleda (Orphanet:87503)
Naegeli-Franceschetti-Jadassohn syndrome (Orphanet:69087)
Oculodentodigital dysplasia (Orphanet:2710)
Oculotrichodysplasia (Orphanet:2718)
Renal tubulopathy - encephalopathy - liver failure (Orphanet:254902)
TRICHOTHIODYSTROPHY, PHOTOSENSITIVE (OMIM:601675)
Tricho-dento-osseous syndrome (Orphanet:3352)
Woolly hair-palmoplantar keratoderma-dilated cardiomyopathy syndrome (Orphanet:65282)
Wrinkly skin syndrome (Orphanet:2834)