Generalized hypotonia

Symptom Information:

Symptom ID: HPO:0001290
Synonyms:
Generalized muscular hypotonia [HPO:0001290]
Hypotonia, generalized [HPO:0001290]
Generalized hypotonia [OMIM:Generalized hypotonia]
Generalized muscular hypotonia [OMIM:Generalized muscular hypotonia]
Hypotonia, generalized [OMIM:Hypotonia, generalized]
Hypotonia, generalized (in some patients) [OMIM:Hypotonia, generalized (in some patients)]
Quality:
Cross references:
OMIM: "Generalized hypotonia" [OMIM:Generalized hypotonia]
OMIM: "Generalized muscular hypotonia" [OMIM:Generalized muscular hypotonia]
OMIM: "Hypotonia, generalized" [OMIM:Hypotonia, generalized]
OMIM: "Hypotonia, generalized (in some patients)" [OMIM:Hypotonia, generalized (in some patients)]
Is a (Direct Parents):
HPO         Muscular hypotonia
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle physiology(HPO:0011804)
             Abnormal muscle tone(HPO:0003808)
                Muscular hypotonia(HPO:0001252)
                   Generalized hypotonia(HPO:0001290)
MedDRA:
Database Frequency: 51 / 7739
Resource:

All diseases associated with this symptom:

17p11.2 microduplication syndrome (Orphanet:1713)
Acrocallosal syndrome (Orphanet:36)
Adducted thumbs - arthrogryposis, Christian type (Orphanet:2952)
Adenylosuccinate lyase deficiency (Orphanet:46)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Bardet-Biedl syndrome 12 (OMIM:615989)
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2R (OMIM:615490)
CHROMOSOME 16p12.1 DELETION SYNDROME, 520-KBFRAGILE SITE, DISTAMYCIN A TYPE, RARE, FRA(16)(p12.1), INCLUDED (OMIM:136570)
CK syndrome (Orphanet:251383)
Combined oxidative phosphorylation defect type 13 (Orphanet:319514)
Congenital muscular dystrophy type 1B (Orphanet:98893)
Corpus callosum agenesis - neuronopathy (Orphanet:1496)
Craniofacial dyssynostosis (Orphanet:1516)
ETHANOLAMINOSIS (OMIM:227150)
Fetal Gaucher disease (Orphanet:85212)
Gaucher disease type 2 (Orphanet:77260)
Hypotonia with lactic acidemia and hyperammonemia (Orphanet:137908)
Joubert syndrome 5 (OMIM:610188)
Koolen-De Vries syndrome (Orphanet:96169)
LUJAN-FRYNS SYNDROME (OMIM:309520)
Larsen-like syndrome, B3GAT3 type (Orphanet:284139)
Leber congenital amaurosis 10 (OMIM:611755)
Leigh syndrome (Orphanet:506)
Lesch-Nyhan syndrome (Orphanet:510)
Lethal ataxia with deafness and optic atrophy (Orphanet:1187)
MEGDEL syndrome (Orphanet:352328)
MGAT2-CDG (Orphanet:79329)
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1 (OMIM:257300)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 3 (OMIM:253280)
MYASTHENIC SYNDROME, CONGENITAL, 4A, SLOW-CHANNEL (OMIM:605809)
Maternally-inherited Leigh syndrome (Orphanet:255210)
Mitochondrial myopathy with reversible cytochrome C oxidase deficiency (Orphanet:254864)
Monosomy 22q13 (Orphanet:48652)
Mosaic variegated aneuploidy syndrome (Orphanet:1052)
Multiple acyl-CoA dehydrogenase deficiency (Orphanet:26791)
NOONAN SYNDROME 6 (OMIM:613224)
OSTEOGENESIS IMPERFECTA, TYPE X (OMIM:613848)
Perinatal lethal hypophosphatasia (Orphanet:247623)
Phosphoribosylpyrophosphate synthetase superactivity (Orphanet:3222)
Prader-Willi syndrome (Orphanet:739)
Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency (Orphanet:88618)
Pyruvate dehydrogenase E1-alpha deficiency (Orphanet:79243)
Pyruvate dehydrogenase E1-beta deficiency (Orphanet:255138)
Radio-ulnar synostosis - intellectual deficit - hypotonia (Orphanet:3270)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Short chain acyl-CoA dehydrogenase deficiency (Orphanet:26792)
Smith-Lemli-Opitz syndrome (Orphanet:818)
Smith-Magenis syndrome (Orphanet:819)
Wolf-Hirschhorn syndrome (Orphanet:280)
X-linked Charcot-Marie-Tooth disease type 5 (Orphanet:99014)
X-linked intellectual deficit, Najm type (Orphanet:163937)