Symptom Information: Sort according to HPO 

1
 (HPO:0002007) Frontal bossing Very frequent [Orphanet] 366 / 7739
2
 (HPO:0000768) Pectus carinatum Very frequent [Orphanet] 136 / 7739
3
 (HPO:0000365) Hearing impairment Very frequent [Orphanet] 539 / 7739
4
 (HPO:0011800) Midface retrusion Very frequent [Orphanet] 221 / 7739
5
 (HPO:0000625) Cleft eyelid Very frequent [Orphanet] 31 / 7739
6
 (HPO:0000303) Mandibular prognathia Very frequent [Orphanet] 179 / 7739
7
 (HPO:0000232) Everted lower lip vermilion Very frequent [Orphanet] 90 / 7739
8
 (HPO:0000316) Hypertelorism Very frequent [Orphanet] 644 / 7739
9
 (HPO:0004322) Short stature Very frequent [Orphanet] 1232 / 7739
10
 (HPO:0000689) Dental malocclusion Very frequent [Orphanet] 114 / 7739
11
 (HPO:0000047) Hypospadias Very frequent [Orphanet] 250 / 7739
12
 (HPO:0000410) Mixed hearing impairment 22 / 7739
13
 (HPO:0000636) Upper eyelid coloboma 7 / 7739
14
 (HPO:0001633) Abnormality of the mitral valve Very frequent [Orphanet] 69 / 7739
15
 (HPO:0001702) Abnormality of the tricuspid valve Very frequent [Orphanet] 32 / 7739
16
 (HPO:0002690) Large sella turcica 12 / 7739
17
 (HPO:0004492) Widely patent fontanelles and sutures 11 / 7739
18
 (HPO:0011120) Concave nasal ridge 9 / 7739
19
 (OMIM) Thick philtrum 1 / 7739
20
 (OMIM) Midline nasal cleft 1 / 7739
21
 (OMIM) Prominent lips 7 / 7739
22
 (HPO:0010537) Wide cranial sutures 21 / 7739
23
 (OMIM) Large, prominent sella turcica 1 / 7739
24
 (HPO:0000366) Abnormality of the nose Very frequent [Orphanet] 56 / 7739
25
 (HPO:0012758) Neurodevelopmental delay Very frequent [Orphanet] 949 / 7739
26
 (HPO:0000007) Autosomal recessive inheritance 2538 / 7739
27
 (HPO:0000272) Malar flattening 277 / 7739
28
 (HPO:0012471) Thick vermilion border 115 / 7739