Symptom Information: Sort according to HPO 

1
 (HPO:0000974) Hyperextensible skin Very frequent [Orphanet] 59 / 7739
2
 (HPO:0001252) Muscular hypotonia 990 / 7739
3
 (HPO:0001324) Muscle weakness Very frequent [Orphanet] 859 / 7739
4
 (HPO:0010547) Muscle flaccidity 466 / 7739
5
 (HPO:0004322) Short stature Very frequent [Orphanet] 1232 / 7739
6
 (HPO:0100678) Premature skin wrinkling Frequent [Orphanet] 25 / 7739
7
 (HPO:0000951) Abnormality of the skin Frequent [Orphanet] 147 / 7739
8
 (HPO:0004299) Hernia of the abdominal wall Frequent [Orphanet] 176 / 7739
9
 (HPO:0000938) Osteopenia 138 / 7739
10
 (HPO:0001382) Joint hypermobility Very frequent [Orphanet] 231 / 7739
11
 (HPO:0000978) Bruising susceptibility 123 / 7739
12
 (HPO:0001058) Poor wound healing 9 / 7739
13
 (HPO:0001075) Atrophic scars 15 / 7739
14
 (HPO:0001623) Breech presentation 16 / 7739
15
 (HPO:0002194) Delayed gross motor development 37 / 7739
16
 (HPO:0002650) Scoliosis 705 / 7739
17
 (HPO:0002808) Kyphosis 289 / 7739
18
 (HPO:0003088) Premature osteoarthritis 10 / 7739
19
 (HPO:0004349) Reduced bone mineral density Occasional [Orphanet] 165 / 7739
20
 (HPO:0008780) Congenital bilateral hip dislocation 4 / 7739
21
 (HPO:0011800) Midface retrusion 221 / 7739
22
 (OMIM) Mild to moderate short stature 7 / 7739
23
 (OMIM) Joint laxity, severe 3 / 7739
24
 (OMIM) Recurrent joint subluxation 3 / 7739
25
 (MedDRA:10017322) Fractures 18 / 7739
26
 (MedDRA:10017076) Fracture 18 / 7739
27
 (OMIM) Thin, velvety skin 3 / 7739
28
 (HPO:0008947) Infantile muscular hypotonia 482 / 7739
29
 (HPO:0000987) Atypical scarring of skin Very frequent [Orphanet] 58 / 7739
30
 (HPO:0002577) Abnormality of the stomach Frequent [Orphanet] 84 / 7739