Symptom Information: Sort according to HPO 

1
 (HPO:0001387) Joint stiffness Occasional [Orphanet] 322 / 7739
2
 (HPO:0000572) Visual loss Occasional [Orphanet] 272 / 7739
3
 (HPO:0001025) Urticaria Very frequent [Orphanet] 73 / 7739
4
 (HPO:0002007) Frontal bossing Frequent [Orphanet] 366 / 7739
5
 (HPO:0010622) Neoplasm of the skeletal system Frequent [Orphanet] 30 / 7739
6
 (HPO:0003326) Myalgia Very frequent [Orphanet] 143 / 7739
7
 (HPO:0001903) Anemia Frequent [Orphanet] 289 / 7739
8
 (HPO:0000505) Visual impairment Frequent [Orphanet] 297 / 7739
9
 (HPO:0009830) Peripheral neuropathy Frequent [Orphanet] 206 / 7739
10
 (HPO:0002716) Lymphadenopathy Frequent [Orphanet] 129 / 7739
11
 (HPO:0005059) Arthralgia/arthritis Very frequent [Orphanet] 141 / 7739
12
 (HPO:0100769) Synovitis Frequent [Orphanet] 86 / 7739
13
 (HPO:0002315) Headache Very frequent [Orphanet] 175 / 7739
14
 (HPO:0000520) Proptosis Frequent [Orphanet] 192 / 7739
15
 (HPO:0000256) Macrocephaly Frequent [Orphanet] 298 / 7739
16
 (HPO:0000239) Large fontanelles Frequent [Orphanet] 135 / 7739
17
 (HPO:0011227) Elevated C-reactive protein level Very frequent [Orphanet] 55 / 7739
18
 (HPO:0002652) Skeletal dysplasia Frequent [Orphanet] 113 / 7739
19
 (HPO:0000365) Hearing impairment Very frequent [Orphanet] 539 / 7739
20
 (HPO:0001874) Abnormality of neutrophils Very frequent [Orphanet] 47 / 7739
21
 (HPO:0001872) Abnormality of thrombocytes Frequent [Orphanet] 20 / 7739
22
 (HPO:0001744) Splenomegaly Frequent [Orphanet] 337 / 7739
23
 (HPO:0002516) Increased intracranial pressure Very frequent [Orphanet] 47 / 7739
24
 (HPO:0002240) Hepatomegaly Frequent [Orphanet] 467 / 7739
25
 (HPO:0001622) Premature birth Occasional [Orphanet] 100 / 7739
26
 (HPO:0100654) Retrobulbar optic neuritis Occasional [Orphanet] 5 / 7739
27
 (HPO:0002017) Nausea and vomiting Very frequent [Orphanet] 134 / 7739
28
 (HPO:0004279) Short palm Very frequent [Orphanet] 323 / 7739
29
 (HPO:0000407) Sensorineural hearing impairment Very frequent [Orphanet] 524 / 7739
30
 (HPO:0001945) Fever Very frequent [Orphanet] 218 / 7739
31
 (HPO:0001287) Meningitis Very frequent [Orphanet] 46 / 7739
32
 (HPO:0001974) Leukocytosis Frequent [Orphanet] 33 / 7739
33
 (HPO:0000969) Edema Frequent [Orphanet] 117 / 7739
34
 (HPO:0001933) Subcutaneous hemorrhage Occasional [Orphanet] 50 / 7739
35
 (HPO:0004349) Reduced bone mineral density Occasional [Orphanet] 165 / 7739
36
 (HPO:0100533) Inflammatory abnormality of the eye Very frequent [Orphanet] 70 / 7739
37
 (OMIM) Stiff skin Very frequent [Orphanet] 31 / 7739
38
 (HPO:0001324) Muscle weakness Very frequent [Orphanet] 859 / 7739
39
 (HPO:0100774) Hyperostosis Very frequent [Orphanet] 17 / 7739
40
 (HPO:0012795) Abnormality of the optic disc Very frequent [Orphanet] 187 / 7739
41
 (HPO:0030350) Erythematous papule Very frequent [Orphanet] 123 / 7739
42
 (HPO:0004325) Decreased body weight Occasional [Orphanet] 492 / 7739
43
 (HPO:0012758) Neurodevelopmental delay Occasional [Orphanet] 949 / 7739
44
 (HPO:0001367) Abnormal joint morphology Frequent [Orphanet] 53 / 7739
45
 (HPO:0011830) Abnormality of oral mucosa Very frequent [Orphanet] 47 / 7739