|
1
|
(HPO:0001250)
|
Seizures |
Frequent [Orphanet]
|
|
|
|
1245 / 7739
|
|
2
|
(HPO:0002315)
|
Headache |
Very frequent [Orphanet]
|
|
|
|
175 / 7739
|
|
3
|
(HPO:0002514)
|
Cerebral calcification |
Frequent [Orphanet]
|
|
|
|
89 / 7739
|
|
4
|
(HPO:0000708)
|
Behavioral abnormality |
Very frequent [Orphanet]
|
|
|
|
212 / 7739
|
|
5
|
(HPO:0000726)
|
Dementia |
|
|
|
|
131 / 7739
|
|
6
|
(HPO:0001297)
|
Stroke |
|
|
|
|
44 / 7739
|
|
7
|
(HPO:0002140)
|
Ischemic stroke |
Frequent [Orphanet]
|
|
|
|
70 / 7739
|
|
8
|
(HPO:0002170)
|
Intracranial hemorrhage |
Very frequent [Orphanet]
|
|
|
|
40 / 7739
|
|
9
|
(HPO:0002637)
|
Cerebral ischemia |
|
|
|
|
17 / 7739
|
|
10
|
(HPO:0004938)
|
Tortuous cerebral arteries |
|
|
|
|
6 / 7739
|
|
11
|
(HPO:0004968)
|
Recurrent cerebral hemorrhage |
|
|
|
|
1 / 7739
|
|
12
|
(HPO:0011695)
|
Cerebellar hemorrhage |
|
|
|
|
6 / 7739
|
|
13
|
(HPO:0011970)
|
Cerebral amyloid angiopathy |
|
|
|
|
9 / 7739
|
|
14
|
(OMIM)
|
Cerebral artery amyloidosis (amyloid deposition in cerebral arteries) |
|
|
|
|
6 / 7739
|
|
15
|
(OMIM)
|
Recurrent strokes |
|
|
|
|
6 / 7739
|
|
16
|
(MedDRA:10008118)
|
Cerebral infarction |
|
|
|
|
10 / 7739
|
|
17
|
(OMIM)
|
Recurrent cerebral and cerebellar hemorrhage |
|
|
|
|
6 / 7739
|
|
18
|
(OMIM)
|
Microbleeds (less than 5 mm in diameter) occur at the gray-white matter junction in the cerebral hemispheres and cerebellum and do not occur in the thalamus, basal ganglia, or brainstem |
|
|
|
|
6 / 7739
|
|
19
|
(OMIM)
|
Hyaline thickening of cerebral arteries |
|
|
|
|
7 / 7739
|
|
20
|
(OMIM)
|
Dementia, progressive, with onset of disease |
|
|
|
|
6 / 7739
|
|
21
|
(HPO:0001522)
|
Death in infancy |
Occasional [Orphanet]
|
|
|
|
275 / 7739
|
|
22
|
(HPO:0100543)
|
Cognitive impairment |
Very frequent [Orphanet]
|
|
|
|
230 / 7739
|
|
23
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|