Symptom Information: Sort according to HPO 

1
 (HPO:0003416) Spinal canal stenosis Frequent [Orphanet] 28 / 7739
2
 (HPO:0000818) Abnormality of the endocrine system Very frequent [Orphanet] 26 / 7739
3
 (HPO:0000280) Coarse facial features Very frequent [Orphanet] 189 / 7739
4
 (HPO:0000158) Macroglossia Very frequent [Orphanet] 119 / 7739
5
 (HPO:0000164) Abnormality of the teeth Frequent [Orphanet] 291 / 7739
6
 (HPO:0000303) Mandibular prognathia Very frequent [Orphanet] 179 / 7739
7
 (HPO:0002758) Osteoarthritis Very frequent [Orphanet] 78 / 7739
8
 (HPO:0000956) Acanthosis nigricans Occasional [Orphanet] 54 / 7739
9
 (HPO:0000445) Wide nose Very frequent [Orphanet] 190 / 7739
10
 (HPO:0001769) Broad foot Very frequent [Orphanet] 31 / 7739
11
 (HPO:0002315) Headache Frequent [Orphanet] 175 / 7739
12
 (HPO:0000293) Full cheeks Very frequent [Orphanet] 85 / 7739
13
 (HPO:0001805) Thick nail Frequent [Orphanet] 96 / 7739
14
 (HPO:0100540) Palpebral edema Frequent [Orphanet] 31 / 7739
15
 (HPO:0100021) Cerebral palsy Frequent [Orphanet] 36 / 7739
16
 (HPO:0001072) Thickened skin Very frequent [Orphanet] 87 / 7739
17
 (HPO:0000822) Hypertension Frequent [Orphanet] 224 / 7739
18
 (HPO:0001869) Deep plantar creases Very frequent [Orphanet] 14 / 7739
19
 (HPO:0100639) Erectile abnormalities Occasional [Orphanet] 15 / 7739
20
 (HPO:0001061) Acne Occasional [Orphanet] 33 / 7739
21
 (HPO:0002007) Frontal bossing Frequent [Orphanet] 366 / 7739
22
 (HPO:0006191) Deep palmar crease Very frequent [Orphanet] 16 / 7739
23
 (HPO:0100746) Macrodactyly of finger Very frequent [Orphanet] 5 / 7739
24
 (HPO:0005059) Arthralgia/arthritis Very frequent [Orphanet] 141 / 7739
25
 (HPO:0000098) Tall stature Very frequent [Orphanet] 74 / 7739
26
 (HPO:0001608) Abnormality of the voice Frequent [Orphanet] 126 / 7739
27
 (HPO:0000819) Diabetes mellitus Frequent [Orphanet] 131 / 7739
28
 (HPO:0000664) Synophrys Frequent [Orphanet] 112 / 7739
29
 (HPO:0002808) Kyphosis Frequent [Orphanet] 289 / 7739
30
 (HPO:0002104) Apnea Frequent [Orphanet] 106 / 7739
31
 (HPO:0000337) Broad forehead Very frequent [Orphanet] 116 / 7739
32
 (HPO:0000953) Hyperpigmentation of the skin Occasional [Orphanet] 75 / 7739
33
 (HPO:0100829) Galactorrhea Occasional [Orphanet] 7 / 7739
34
 (HPO:0000080) Abnormality of reproductive system physiology Occasional [Orphanet] 6 / 7739
35
 (HPO:0000845) Growth hormone excess 18 / 7739
36
 (HPO:0000858) Menstrual irregularities Frequent [Orphanet] 42 / 7739
37
 (HPO:0001633) Abnormality of the mitral valve Occasional [Orphanet] 69 / 7739
38
 (HPO:0001638) Cardiomyopathy Occasional [Orphanet] 192 / 7739
39
 (HPO:0001712) Left ventricular hypertrophy 76 / 7739
40
 (HPO:0002893) Pituitary adenoma 16 / 7739
41
 (OMIM) Increased height 3 / 7739
42
 (OMIM) Mandibular enlargement 4 / 7739
43
 (OMIM) Galactorrhea from increased serum prolactin 3 / 7739
44
 (OMIM) Enlarged hands 3 / 7739
45
 (OMIM) Enlarged feet 3 / 7739
46
 (OMIM) Anterior pituitary adenoma 3 / 7739
47
 (OMIM) Cushing disease due to increased ACTH secretion (less common) 3 / 7739
48
 (OMIM) Somatotrophinoma 3 / 7739
49
 (MedDRA:10036832) Prolactinoma 5 / 7739
50
 (OMIM) Increased serum growth hormone levels 3 / 7739
51
 (OMIM) Increased serum IGF1 3 / 7739
52
 (OMIM) Increased serum prolactin 3 / 7739
53
 (HPO:0000277) Abnormality of the mandible Frequent [Orphanet] 394 / 7739
54
 (HPO:0011750) Neoplasm of the anterior pituitary Frequent [Orphanet] 6 / 7739
55
 (HPO:0000763) Sensory neuropathy Frequent [Orphanet] 78 / 7739
56
 (HPO:0100851) Abnormal emotion/affect behavior Frequent [Orphanet] 85 / 7739
57
 (HPO:0001324) Muscle weakness Very frequent [Orphanet] 859 / 7739
58
 (HPO:0011037) Decreased urine output Occasional [Orphanet] 47 / 7739
59
 (HPO:0002360) Sleep disturbance Occasional [Orphanet] 113 / 7739
60
 (HPO:0012471) Thick vermilion border Very frequent [Orphanet] 115 / 7739
61
 (HPO:0011362) Abnormal hair quantity Frequent [Orphanet] 92 / 7739
62
 (HPO:0001357) Plagiocephaly Very frequent [Orphanet] 106 / 7739
63
 (HPO:0040075) Hypopituitarism Very frequent [Orphanet] 32 / 7739