|
1
|
(HPO:0001657)
|
Prolonged QT interval |
Very frequent [IBIS]
|
100% (n=160)
|
20301579
|
IBIS
|
33 / 7739
|
|
2
|
(HPO:0008527)
|
Congenital sensorineural hearing impairment |
Very frequent [IBIS]
|
|
9164812
|
IBIS
|
165 / 7739
|
|
3
|
(HPO:0008619)
|
Bilateral sensorineural hearing impairment |
Very frequent [IBIS]
|
|
9164812
|
IBIS
|
23 / 7739
|
|
4
|
(HPO:0001695)
|
Cardiac arrest |
Frequent [IBIS]
|
39% (n=186)
|
9164812
|
IBIS
|
87 / 7739
|
|
5
|
(HPO:0001279)
|
Syncope |
Frequent [IBIS]
|
|
9164812
|
IBIS
|
94 / 7739
|
|
6
|
(HPO:0001891)
|
Iron deficiency anemia |
Frequent [IBIS]
|
|
20301579
|
IBIS
|
22 / 7739
|
|
7
|
(MedDRA:10005545)
|
Blood gastrin increased |
Frequent [IBIS]
|
|
20301579
|
IBIS
|
1 / 7739
|
|
8
|
(HPO:0001645)
|
Sudden cardiac death |
Occasional [IBIS]
|
27% (n=186)
|
20301579
|
IBIS
|
84 / 7739
|
|
9
|
(HPO:0001664)
|
Torsade de pointes |
|
|
9164812
|
IBIS
|
15 / 7739
|
|
10
|
(HPO:0004756)
|
Ventricular tachycardia |
|
|
9164812
|
IBIS
|
55 / 7739
|
|
11
|
(HPO:0001663)
|
Ventricular fibrillation |
|
|
9164812
|
IBIS
|
35 / 7739
|
|
12
|
(HPO:0001250)
|
Seizures |
|
|
23668803
|
IBIS
|
1245 / 7739
|
|
13
|
(HPO:0012266)
|
T-wave alternans |
|
|
26022593
|
IBIS
|
8 / 7739
|
|
14
|
(HPO:0002194)
|
Delayed gross motor development |
|
|
25471708
|
IBIS
|
37 / 7739
|
|
15
|
(HPO:0001751)
|
Vestibular dysfunction |
|
|
25471708
|
IBIS
|
19 / 7739
|
|
16
|
(HPO:0002242)
|
Abnormality of the intestine |
|
|
22805636
|
IBIS
|
42 / 7739
|
|
17
|
(HPO:0002014)
|
Diarrhea |
|
|
22805636
|
IBIS
|
225 / 7739
|
|
18
|
(HPO:0010872)
|
EKG: T-wave inversion |
|
|
7721491
|
IBIS
|
19 / 7739
|
|
19
|
(HPO:0011097)
|
Epileptic spasms |
|
|
23668803
|
IBIS
|
45 / 7739
|
|
20
|
(HPO:0004308)
|
Ventricular arrhythmia |
|
|
22539601
|
IBIS
|
46 / 7739
|