1
|
(HPO:0011838)
|
Sclerodactyly |
Very frequent [IBIS]
|
96%(n=268)
|
24122180
|
IBIS
|
8 / 7739
|
2
|
(OMIM)
|
Raynaud syndrome |
Very frequent [IBIS]
|
95%(n=6690)
|
19279015
|
IBIS
|
3 / 7739
|
3
|
(HPO:0100324)
|
Scleroderma |
Very frequent [IBIS]
|
|
24122180
|
IBIS
|
6 / 7739
|
4
|
(HPO:0003493)
|
Antinuclear antibody positivity |
Frequent [IBIS]
|
88%(n=1029)
|
24646463
|
IBIS
|
15 / 7739
|
5
|
(HPO:0002093)
|
Respiratory insufficiency |
Frequent [IBIS]
|
67%(n=117)
|
17133611
|
IBIS
|
410 / 7739
|
6
|
(HPO:0006530)
|
Interstitial pulmonary disease |
Frequent [IBIS]
|
49%(n=268)
|
24122180
|
IBIS
|
26 / 7739
|
7
|
(HPO:0200042)
|
Skin ulcer |
Frequent [IBIS]
|
40%(n=268)
|
24122180
|
IBIS
|
138 / 7739
|
8
|
(HPO:0100585)
|
Telangiectasia of the skin |
Frequent [IBIS]
|
39%(n=268)
|
24122180
|
IBIS
|
66 / 7739
|
9
|
(HPO:0000987)
|
Atypical scarring of skin |
Frequent [IBIS]
|
39%(n=268)
|
24122180
|
IBIS
|
58 / 7739
|
10
|
(HPO:0100639)
|
Erectile abnormalities |
Frequent [IBIS]
|
38%(n=130)
|
22348608
|
IBIS
|
15 / 7739
|
11
|
(HPO:0002206)
|
Pulmonary fibrosis |
Frequent [IBIS]
|
37%(n=43)
|
25030848
|
IBIS
|
51 / 7739
|
12
|
(HPO:0000670)
|
Carious teeth |
Frequent [IBIS]
|
|
3422721
|
IBIS
|
145 / 7739
|
13
|
(HPO:0000217)
|
Xerostomia |
Frequent [IBIS]
|
|
3422721
|
IBIS
|
35 / 7739
|
14
|
(HPO:0000142)
|
Abnormality of the vagina |
Frequent [IBIS]
|
|
7856689
|
IBIS
|
24 / 7739
|
15
|
(HPO:0002020)
|
Gastroesophageal reflux |
Occasional [IBIS]
|
30%(n=150)
|
17133611
|
IBIS
|
101 / 7739
|
16
|
(HPO:0001324)
|
Muscle weakness |
Occasional [IBIS]
|
27%(n=117)
|
17133611
|
IBIS
|
859 / 7739
|
17
|
(HPO:0004325)
|
Decreased body weight |
Occasional [IBIS]
|
27%(n=153)
|
17133611
|
IBIS
|
492 / 7739
|
18
|
(HPO:0005059)
|
Arthralgia/arthritis |
Occasional [IBIS]
|
24.5%(n=930)
|
24646463
|
IBIS
|
141 / 7739
|
19
|
(HPO:0002015)
|
Dysphagia |
Occasional [IBIS]
|
24%(n=152)
|
17133611
|
IBIS
|
301 / 7739
|
20
|
(HPO:0003761)
|
Calcinosis |
Occasional [IBIS]
|
20%(n=980)
|
24646463
|
IBIS
|
12 / 7739
|
21
|
(HPO:0009830)
|
Peripheral neuropathy |
Occasional [IBIS]
|
18%(n=155)
|
24646463
|
IBIS
|
206 / 7739
|
22
|
(HPO:0100545)
|
Arterial stenosis |
Occasional [IBIS]
|
11%(n=831)
|
24646463
|
IBIS
|
22 / 7739
|
23
|
(HPO:0011675)
|
Arrhythmia |
Occasional [IBIS]
|
10%(n=153)
|
17133611
|
IBIS
|
226 / 7739
|
24
|
(HPO:0001000)
|
Abnormality of skin pigmentation |
Occasional [IBIS]
|
|
25030848
|
IBIS
|
105 / 7739
|
25
|
(HPO:0100769)
|
Synovitis |
Occasional [IBIS]
|
|
7073343
|
IBIS
|
86 / 7739
|
26
|
(HPO:0100614)
|
Myositis |
Rare [IBIS]
|
7%(n=928)
|
24646463
|
IBIS
|
21 / 7739
|
27
|
(HPO:0000822)
|
Hypertension |
Rare [IBIS]
|
7%(n=153)
|
17133611
|
IBIS
|
224 / 7739
|
28
|
(HPO:0002092)
|
Pulmonary hypertension |
Rare [IBIS]
|
7%(n=268)
|
24122180
|
IBIS
|
109 / 7739
|
29
|
(HPO:0001701)
|
Pericarditis |
Rare [IBIS]
|
5%(n=837)
|
24646463
|
IBIS
|
13 / 7739
|
30
|
(HPO:0001711)
|
Abnormality of the left ventricle |
Rare [IBIS]
|
5%(n=7073)
|
19279015
|
IBIS
|
22 / 7739
|
31
|
(HPO:0100749)
|
Chest pain |
Rare [IBIS]
|
3%(n=566)
|
16320330
|
IBIS
|
92 / 7739
|
32
|
(HPO:0001635)
|
Congestive heart failure |
Rare [IBIS]
|
3%(n=117)
|
17133611
|
IBIS
|
232 / 7739
|
33
|
(HPO:0001250)
|
Seizures |
Rare [IBIS]
|
|
17133611
|
IBIS
|
1245 / 7739
|
34
|
(HPO:0002024)
|
Malabsorption |
|
|
17329309
|
IBIS
|
142 / 7739
|
35
|
(HPO:0001063)
|
Acrocyanosis |
|
|
17107383
|
IBIS
|
56 / 7739
|
36
|
(HPO:0004326)
|
Cachexia |
|
|
9714351
|
IBIS
|
71 / 7739
|
37
|
(HPO:0010783)
|
Erythema |
|
|
25030848
|
IBIS
|
138 / 7739
|