1
|
(HPO:0011034)
|
Amyloidosis |
Very frequent [IBIS]
|
|
17093068
|
IBIS
|
12 / 7739
|
2
|
(HPO:0006775)
|
Multiple myeloma |
Frequent [IBIS]
|
|
16107109
|
IBIS
|
10 / 7739
|
3
|
(MedDRA:10007509)
|
Cardiac amyloidosis |
Frequent [IBIS]
|
|
16107109; 10659664
|
IBIS
|
5 / 7739
|
4
|
(HPO:0000100)
|
Nephrotic syndrome |
Frequent [IBIS]
|
|
16107109
|
IBIS
|
83 / 7739
|
5
|
(HPO:0007141)
|
Sensorimotor neuropathy |
Frequent [IBIS]
|
|
16107109
|
IBIS
|
27 / 7739
|
6
|
(HPO:0002240)
|
Hepatomegaly |
Frequent [IBIS]
|
|
16107109
|
IBIS
|
467 / 7739
|
7
|
(HPO:0001744)
|
Splenomegaly |
Frequent [IBIS]
|
|
16107109
|
IBIS
|
337 / 7739
|
8
|
(HPO:0000158)
|
Macroglossia |
Occasional [IBIS]
|
|
16107109
|
IBIS
|
119 / 7739
|
9
|
(OMIM)
|
High M-component |
|
|
18708629
|
IBIS
|
3 / 7739
|
10
|
(MedDRA:10060880)
|
Monoclonal gammopathy |
|
|
18708629
|
IBIS
|
5 / 7739
|
11
|
(OMIM)
|
Primary immunoglobulin-related amyloidosis (AL) |
|
|
16107109
|
IBIS
|
3 / 7739
|
12
|
(OMIM)
|
Paraproteinemia |
|
|
18708629
|
IBIS
|
3 / 7739
|
13
|
(HPO:0001635)
|
Congestive heart failure |
|
|
16107109
|
IBIS
|
232 / 7739
|
14
|
(HPO:0011675)
|
Arrhythmia |
|
|
16107109
|
IBIS
|
226 / 7739
|
15
|
(MedDRA:10047240)
|
Venous pressure jugular increased |
|
|
16107109
|
IBIS
|
6 / 7739
|
16
|
(OMIM)
|
Poor R-wave progression on electrocardiogram |
|
|
16107109
|
IBIS
|
2 / 7739
|
17
|
(HPO:0005110)
|
Atrial fibrillation |
|
|
16107109
|
IBIS
|
71 / 7739
|
18
|
(HPO:0001645)
|
Sudden cardiac death |
|
|
16107109
|
IBIS
|
84 / 7739
|
19
|
(HPO:0001685)
|
Myocardial fibrosis |
|
|
16107109
|
IBIS
|
30 / 7739
|
20
|
(HPO:0003116)
|
Abnormal echocardiogram |
|
|
16107109
|
IBIS
|
33 / 7739
|
21
|
(MedDRA:10013002)
|
Dilatation atrial |
|
|
16107109
|
IBIS
|
1 / 7739
|
22
|
(HPO:0001698)
|
Pericardial effusion |
|
|
16107109
|
IBIS
|
20 / 7739
|
23
|
(HPO:0030156)
|
Bence Jones Proteinuria |
|
|
23337445
|
IBIS
|
2 / 7739
|
24
|
(HPO:0012597)
|
Heavy proteinuria |
|
|
23337445
|
IBIS
|
2 / 7739
|
25
|
(MedDRA:10052337)
|
Diastolic dysfunction |
|
|
23337445
|
IBIS
|
14 / 7739
|
26
|
(HPO:0003073)
|
Hypoalbuminemia |
|
|
23337445
|
IBIS
|
40 / 7739
|
27
|
(HPO:0001279)
|
Syncope |
|
|
23337445
|
IBIS
|
94 / 7739
|
28
|
(HPO:0001677)
|
Coronary artery disease |
|
|
23337445
|
IBIS
|
58 / 7739
|
29
|
(HPO:0001638)
|
Cardiomyopathy |
|
|
23337445
|
IBIS
|
192 / 7739
|
30
|
(MedDRA:10048620)
|
Intracardiac thrombus |
|
|
23337445
|
IBIS
|
2 / 7739
|
31
|
(MedDRA:10059245)
|
Angiopathy |
|
|
23337445
|
IBIS
|
3 / 7739
|
32
|
(HPO:0001644)
|
Dilated cardiomyopathy |
|
|
23337445
|
IBIS
|
141 / 7739
|
33
|
(HPO:0002014)
|
Diarrhea |
|
|
11705429
|
IBIS
|
225 / 7739
|
34
|
(HPO:0002024)
|
Malabsorption |
|
|
11705429
|
IBIS
|
142 / 7739
|
35
|
(HPO:0002570)
|
Steatorrhea |
|
|
11705429
|
IBIS
|
31 / 7739
|
36
|
(HPO:0002039)
|
Anorexia |
|
|
11705429
|
IBIS
|
62 / 7739
|
37
|
(HPO:0002321)
|
Vertigo |
|
|
11705429
|
IBIS
|
58 / 7739
|
38
|
(HPO:0001824)
|
Weight loss |
|
|
11705429
|
IBIS
|
42 / 7739
|
39
|
(HPO:0002615)
|
Hypotension |
|
|
11705429
|
IBIS
|
52 / 7739
|
40
|
(HPO:0012280)
|
Hepatic amyloidosis |
|
|
17093068
|
IBIS
|
4 / 7739
|
41
|
(MedDRA:10059250)
|
Gastrointestinal amyloidosis |
|
|
17093068
|
IBIS
|
2 / 7739
|
42
|
(MedDRA:10036673)
|
Primary amyloidosis |
|
|
26708800
|
IBIS
|
3 / 7739
|
43
|
(MedDRA:10005372)
|
Blood blister |
|
|
26708800
|
IBIS
|
2 / 7739
|
44
|
(HPO:0200097)
|
Oral mucosal blisters |
|
|
26708800
|
IBIS
|
7 / 7739
|
45
|
(HPO:0000979)
|
Purpura |
|
|
26708800
|
IBIS
|
27 / 7739
|
46
|
(HPO:0001030)
|
Fragile skin |
|
|
26390868
|
IBIS
|
25 / 7739
|
47
|
(HPO:0000967)
|
Petechiae |
|
|
26390868
|
IBIS
|
26 / 7739
|
48
|
(MedDRA:10006513)
|
Bruising, ecchymosis and purpura |
|
|
26390868
|
IBIS
|
3 / 7739
|
49
|
(HPO:0030150)
|
Plasmacytosis |
|
|
26390868
|
IBIS
|
3 / 7739
|
50
|
(HPO:0003473)
|
Fatigable weakness |
|
|
26390868
|
IBIS
|
39 / 7739
|
51
|
(HPO:0000174)
|
Abnormality of the palate |
|
|
267888
|
IBIS
|
298 / 7739
|
52
|
(HPO:0010944)
|
Abnormality of the renal pelvis |
|
|
1632328
|
IBIS
|
3 / 7739
|
53
|
(HPO:0000502)
|
Abnormality of the conjunctiva |
|
|
8464207
|
IBIS
|
6 / 7739
|
54
|
(HPO:0000492)
|
Abnormality of the eyelid |
|
|
8464207
|
IBIS
|
41 / 7739
|
55
|
(HPO:0010288)
|
Abnormality of the sublingual glands |
|
|
9745189
|
IBIS
|
2 / 7739
|
56
|
(IBIS)
|
Pulmonary primary localized amyloidosis |
|
|
17244928
|
IBIS
|
2 / 7739
|
57
|
(IBIS)
|
Lacrimal gland primary localized amyloidosis |
|
|
19861750
|
IBIS
|
2 / 7739
|
58
|
(HPO:0011482)
|
Abnormality of the lacrimal gland |
|
|
19861750
|
IBIS
|
2 / 7739
|
59
|
(IBIS)
|
Penile primary localized amyloidosis |
|
|
17645099
|
IBIS
|
2 / 7739
|
60
|
(HPO:0002832)
|
Calcific stippling |
|
|
17704307
|
IBIS
|
5 / 7739
|
61
|
(IBIS)
|
Stippled calcification in the right supraclavicular area and mediastinum |
|
|
17704307
|
IBIS
|
2 / 7739
|
62
|
(IBIS)
|
Thoracic primary localized amyloidosis |
|
|
17704307
|
IBIS
|
2 / 7739
|
63
|
(HPO:0100721)
|
Mediastinal lymphadenopathy |
|
|
17704307
|
IBIS
|
19 / 7739
|
64
|
(IBIS)
|
Urogenital primary localized amyloidosis |
|
|
24693509
|
IBIS
|
2 / 7739
|
65
|
(IBIS)
|
Duodenal primary localized amyloidosis |
|
|
17296522
|
IBIS
|
2 / 7739
|
66
|
(HPO:0012716)
|
Moderate conductive hearing impairment |
|
|
21571465
|
IBIS
|
2 / 7739
|
67
|
(HPO:0002778)
|
Abnormality of the trachea |
|
|
21571465
|
IBIS
|
3 / 7739
|
68
|
(HPO:0000421)
|
Epistaxis |
|
|
21571465
|
IBIS
|
85 / 7739
|
69
|
(IBIS)
|
Facial pain |
|
|
21571465
|
IBIS
|
2 / 7739
|
70
|
(HPO:0000458)
|
Anosmia |
|
|
21571465
|
IBIS
|
49 / 7739
|
71
|
(IBIS)
|
Nasal primary localized amyloidosis |
|
|
21571465
|
IBIS
|
2 / 7739
|
72
|
(IBIS)
|
Ureteric primary localized amyloidosis |
|
|
22020852
|
IBIS
|
2 / 7739
|
73
|
(MedDRA:10026865)
|
Mass |
|
|
22184002
|
IBIS
|
2 / 7739
|
74
|
(HPO:0000602)
|
Ophthalmoplegia |
|
|
22184002
|
IBIS
|
56 / 7739
|
75
|
(HPO:0000520)
|
Proptosis |
|
|
22184002
|
IBIS
|
192 / 7739
|
76
|
(IBIS)
|
Orbital primary localized amyloidosis |
|
|
22184002
|
IBIS
|
2 / 7739
|
77
|
(IBIS)
|
Oropharyngeal primary localized amyloidosis |
|
|
23978123
|
IBIS
|
2 / 7739
|
78
|
(IBIS)
|
Nasopharyngeal primary localized amyloidosis |
|
|
23978123
|
IBIS
|
2 / 7739
|
79
|
(MedDRA:10030983)
|
Oral lichen planus |
|
|
25586447
|
IBIS
|
2 / 7739
|
80
|
(HPO:0009098)
|
Chronic oral candidiasis |
|
|
25586447
|
IBIS
|
5 / 7739
|
81
|
(IBIS)
|
Oral primary localized amyloidosis |
|
|
25586447
|
IBIS
|
2 / 7739
|
82
|
(HPO:0012191)
|
B-cell lymphoma |
|
|
17244928
|
IBIS
|
5 / 7739
|
83
|
(MedDRA:10063945)
|
Pulmonary amyloidosis |
|
|
17244928
|
IBIS
|
2 / 7739
|
84
|
(HPO:0200044)
|
Porokeratosis |
|
|
17397946
|
IBIS
|
11 / 7739
|
85
|
(HPO:0000119)
|
Abnormality of the genitourinary system |
|
|
24693509
|
IBIS
|
34 / 7739
|
86
|
(HPO:0000790)
|
Hematuria |
|
|
24693509
|
IBIS
|
106 / 7739
|