1
|
(HPO:0000083)
|
Renal insufficiency |
Occasional [Orphanet]
|
|
|
|
232 / 7739
|
2
|
(HPO:0000225)
|
Gingival bleeding |
Frequent [Orphanet]
|
|
|
|
28 / 7739
|
3
|
(HPO:0000365)
|
Hearing impairment |
Occasional [Orphanet]
|
|
|
|
539 / 7739
|
4
|
(HPO:0000421)
|
Epistaxis |
Occasional [Orphanet]
|
|
|
|
85 / 7739
|
5
|
(HPO:0000520)
|
Proptosis |
Occasional [Orphanet]
|
|
|
|
192 / 7739
|
6
|
(HPO:0000965)
|
Cutis marmorata |
Occasional [Orphanet]
|
|
|
|
46 / 7739
|
7
|
(HPO:0000980)
|
Pallor |
Frequent [Orphanet]
|
|
|
|
52 / 7739
|
8
|
(HPO:0001025)
|
Urticaria |
Occasional [Orphanet]
|
|
|
|
73 / 7739
|
9
|
(HPO:0001635)
|
Congestive heart failure |
Occasional [Orphanet]
|
|
|
|
232 / 7739
|
10
|
(HPO:0001744)
|
Splenomegaly |
Occasional [Orphanet]
|
|
|
|
337 / 7739
|
11
|
(HPO:0001874)
|
Abnormality of neutrophils |
Frequent [Orphanet]
|
|
|
|
47 / 7739
|
12
|
(HPO:0001897)
|
Normocytic anemia |
Frequent [Orphanet]
|
|
|
|
7 / 7739
|
13
|
(HPO:0001909)
|
Leukemia |
Very frequent [Orphanet]
occasional [HPO:probinson]
|
|
|
|
46 / 7739
|
14
|
(HPO:0001933)
|
Subcutaneous hemorrhage |
Occasional [Orphanet]
|
|
|
|
50 / 7739
|
15
|
(HPO:0002024)
|
Malabsorption |
Occasional [Orphanet]
|
|
|
|
142 / 7739
|
16
|
(HPO:0002039)
|
Anorexia |
Occasional [Orphanet]
|
|
|
|
62 / 7739
|
17
|
(HPO:0002093)
|
Respiratory insufficiency |
Frequent [Orphanet]
|
|
|
|
410 / 7739
|
18
|
(HPO:0002103)
|
Abnormality of the pleura |
Occasional [Orphanet]
|
|
|
|
58 / 7739
|
19
|
(HPO:0002113)
|
Pulmonary infiltrates |
Occasional [Orphanet]
|
|
|
|
36 / 7739
|
20
|
(HPO:0002239)
|
Gastrointestinal hemorrhage |
Occasional [Orphanet]
|
|
|
|
97 / 7739
|
21
|
(HPO:0002240)
|
Hepatomegaly |
Occasional [Orphanet]
|
|
|
|
467 / 7739
|
22
|
(HPO:0002066)
|
Gait ataxia |
Occasional [Orphanet]
|
|
|
|
327 / 7739
|
23
|
(HPO:0002141)
|
Gait imbalance |
Occasional [Orphanet]
|
|
|
|
55 / 7739
|
24
|
(HPO:0002354)
|
Memory impairment |
Occasional [Orphanet]
|
|
|
|
63 / 7739
|
25
|
(HPO:0002716)
|
Lymphadenopathy |
Occasional [Orphanet]
|
|
|
|
129 / 7739
|
26
|
(HPO:0004372)
|
Reduced consciousness/confusion |
Occasional [Orphanet]
|
|
|
|
73 / 7739
|
27
|
(HPO:0006824)
|
Cranial nerve paralysis |
Occasional [Orphanet]
|
|
|
|
81 / 7739
|
28
|
(HPO:0008046)
|
Abnormality of the retinal vasculature |
Occasional [Orphanet]
|
|
|
|
41 / 7739
|
29
|
(HPO:0009830)
|
Peripheral neuropathy |
Occasional [Orphanet]
|
|
|
|
206 / 7739
|
30
|
(HPO:0010741)
|
Edema of the lower limbs |
Occasional [Orphanet]
|
|
|
|
34 / 7739
|
31
|
(HPO:0100724)
|
Hypercoagulability |
Frequent [Orphanet]
|
|
|
|
15 / 7739
|
32
|
(HPO:0100778)
|
Cryoglobulinemia |
Occasional [Orphanet]
|
|
|
|
2 / 7739
|
33
|
(HPO:0002315)
|
Headache |
Occasional [Orphanet]
|
|
|
|
175 / 7739
|
34
|
(HPO:0002140)
|
Ischemic stroke |
Occasional [Orphanet]
|
|
|
|
70 / 7739
|
35
|
(HPO:0011227)
|
Elevated C-reactive protein level |
Occasional [Orphanet]
|
|
|
|
55 / 7739
|
36
|
(HPO:0012089)
|
Arteritis |
Occasional [Orphanet]
|
|
|
|
40 / 7739
|
37
|
(HPO:0001945)
|
Fever |
Occasional [Orphanet]
|
|
|
|
218 / 7739
|
38
|
(HPO:0001324)
|
Muscle weakness |
Occasional [Orphanet]
|
|
|
|
859 / 7739
|
39
|
(HPO:0011442)
|
Abnormality of central motor function |
Occasional [Orphanet]
|
|
|
|
76 / 7739
|
40
|
(HPO:0012145)
|
Abnormality of multiple cell lineages in the bone marrow |
Very frequent [Orphanet]
|
|
|
|
11 / 7739
|
41
|
(HPO:0000606)
|
Abnormality of the periorbital region |
Occasional [Orphanet]
|
|
|
|
96 / 7739
|
42
|
(HPO:0010978)
|
Abnormality of immune system physiology |
Occasional [Orphanet]
|
|
|
|
148 / 7739
|
43
|
(HPO:0004377)
|
Hematological neoplasm |
Very frequent [Orphanet]
|
|
|
|
12 / 7739
|
44
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|
45
|
(HPO:0001271)
|
Polyneuropathy |
|
|
|
|
56 / 7739
|
46
|
(HPO:0002665)
|
Lymphoma |
occasional [HPO:probinson]
|
|
|
|
60 / 7739
|
47
|
(HPO:0003347)
|
Impaired lymphocyte transformation with phytohemagglutinin |
|
|
|
|
6 / 7739
|
48
|
(HPO:0003459)
|
Polyclonal elevation of IgM |
|
|
|
|
4 / 7739
|
49
|
(HPO:0005508)
|
Waldenstrom macroglobulinemia |
|
|
|
|
2 / 7739
|