|
1
|
(HPO:0001635)
|
Congestive heart failure |
Frequent [IBIS]
|
75% (n=63)
|
9197214
|
IBIS
|
232 / 7739
|
|
2
|
(HPO:0001678)
|
Atrioventricular block |
Frequent [IBIS]
|
|
25895034
|
IBIS
|
59 / 7739
|
|
3
|
(HPO:0004756)
|
Ventricular tachycardia |
Occasional [IBIS]
|
|
9197214
|
IBIS
|
55 / 7739
|
|
4
|
(HPO:0001663)
|
Ventricular fibrillation |
Occasional [IBIS]
|
|
25895034
|
IBIS
|
35 / 7739
|
|
5
|
(HPO:0012722)
|
Heart block |
Rare [IBIS]
|
5% (n=63)
|
9197214
|
IBIS
|
5 / 7739
|
|
6
|
(HPO:0001645)
|
Sudden cardiac death |
|
|
26275338
|
IBIS
|
84 / 7739
|
|
7
|
(HPO:0004308)
|
Ventricular arrhythmia |
|
|
26275338
|
IBIS
|
46 / 7739
|
|
8
|
(HPO:0012819)
|
Myocarditis |
|
|
26275338
|
IBIS
|
4 / 7739
|
|
9
|
(HPO:0001700)
|
Myocardial necrosis |
|
|
25895034
|
IBIS
|
6 / 7739
|
|
10
|
(MedDRA:10062049)
|
Lymphocytic infiltration |
|
|
25895034
|
IBIS
|
9 / 7739
|
|
11
|
(HPO:0002094)
|
Dyspnea |
|
|
24444397
|
IBIS
|
132 / 7739
|
|
12
|
(HPO:0002615)
|
Hypotension |
|
|
24444397
|
IBIS
|
52 / 7739
|
|
13
|
(HPO:0100519)
|
Anuria |
|
|
24444397
|
IBIS
|
20 / 7739
|
|
14
|
(HPO:0001945)
|
Fever |
|
|
24444397
|
IBIS
|
218 / 7739
|
|
15
|
(HPO:0002014)
|
Diarrhea |
|
|
24444397
|
IBIS
|
225 / 7739
|
|
16
|
(HPO:0002018)
|
Nausea |
|
|
24444397
|
IBIS
|
44 / 7739
|
|
17
|
(HPO:0100749)
|
Chest pain |
|
|
24444397
|
IBIS
|
92 / 7739
|
|
18
|
(HPO:0005110)
|
Atrial fibrillation |
|
|
16844247
|
IBIS
|
71 / 7739
|
|
19
|
(MedDRA:10007548)
|
Cardiac enzymes increased |
|
|
16844247
|
IBIS
|
4 / 7739
|
|
20
|
(HPO:0001644)
|
Dilated cardiomyopathy |
|
|
16844247
|
IBIS
|
141 / 7739
|
|
21
|
(OMIM)
|
Decreased left ventricular ejection fraction (reported in 1 patient) |
|
|
16844247
|
IBIS
|
2 / 7739
|
|
22
|
(HPO:0012664)
|
Reduced ejection fraction |
|
|
16844247
|
IBIS
|
32 / 7739
|
|
23
|
(HPO:0030149)
|
Cardiogenic shock |
|
|
16844247
|
IBIS
|
4 / 7739
|
|
24
|
(HPO:0009071)
|
Inflammatory myopathy |
|
|
12535829
|
IBIS
|
2 / 7739
|
|
25
|
(HPO:0011712)
|
Right bundle branch block |
|
|
12847057
|
IBIS
|
34 / 7739
|
|
26
|
(HPO:0005180)
|
Tricuspid regurgitation |
|
|
12847057
|
IBIS
|
20 / 7739
|
|
27
|
(HPO:0003546)
|
Exercise intolerance |
|
|
9197214
|
IBIS
|
62 / 7739
|
|
28
|
(HPO:0012764)
|
Orthopnea |
|
|
9197214
|
IBIS
|
9 / 7739
|
|
29
|
(HPO:0012398)
|
Peripheral edema |
|
|
9197214
|
IBIS
|
12 / 7739
|
|
30
|
(HPO:0001962)
|
Palpitations |
|
|
9197214
|
IBIS
|
62 / 7739
|
|
31
|
(HPO:0001279)
|
Syncope |
|
|
9197214
|
IBIS
|
94 / 7739
|