|
1
|
(HPO:0003474)
|
Sensory impairment |
Very frequent [Orphanet]
|
|
|
|
54 / 7739
|
|
2
|
(HPO:0002315)
|
Headache |
Frequent [Orphanet]
|
|
|
|
175 / 7739
|
|
3
|
(HPO:0000708)
|
Behavioral abnormality |
Frequent [Orphanet]
|
|
|
|
212 / 7739
|
|
4
|
(HPO:0002140)
|
Ischemic stroke |
Very frequent [Orphanet]
|
|
|
|
70 / 7739
|
|
5
|
(HPO:0002170)
|
Intracranial hemorrhage |
Very frequent [Orphanet]
|
|
|
|
40 / 7739
|
|
6
|
(HPO:0100659)
|
Abnormality of the cerebral vasculature |
Frequent [Orphanet]
|
|
|
|
25 / 7739
|
|
7
|
(HPO:0002637)
|
Cerebral ischemia |
|
|
|
|
17 / 7739
|
|
8
|
(HPO:0004372)
|
Reduced consciousness/confusion |
Very frequent [Orphanet]
|
|
|
|
73 / 7739
|
|
9
|
(HPO:0004938)
|
Tortuous cerebral arteries |
|
|
|
|
6 / 7739
|
|
10
|
(HPO:0011970)
|
Cerebral amyloid angiopathy |
|
|
|
|
9 / 7739
|
|
11
|
(OMIM)
|
Cerebral artery amyloidosis (amyloid deposition in cerebral arteries) |
|
|
|
|
6 / 7739
|
|
12
|
(OMIM)
|
Recurrent strokes |
|
|
|
|
6 / 7739
|
|
13
|
(MedDRA:10008118)
|
Cerebral infarction |
|
|
|
|
10 / 7739
|
|
14
|
(OMIM)
|
Recurrent cerebral and cerebellar hemorrhage |
|
|
|
|
6 / 7739
|
|
15
|
(OMIM)
|
Microbleeds (less than 5 mm in diameter) occur at the gray-white matter junction in the cerebral hemispheres and cerebellum and do not occur in the thalamus, basal ganglia, or brainstem |
|
|
|
|
6 / 7739
|
|
16
|
(OMIM)
|
Hyaline thickening of cerebral arteries |
|
|
|
|
7 / 7739
|
|
17
|
(OMIM)
|
Dementia, progressive, with onset of disease |
|
|
|
|
6 / 7739
|
|
18
|
(HPO:0011442)
|
Abnormality of central motor function |
Very frequent [Orphanet]
|
|
|
|
76 / 7739
|
|
19
|
(HPO:0012758)
|
Neurodevelopmental delay |
Very frequent [Orphanet]
|
|
|
|
949 / 7739
|
|
20
|
(HPO:0001522)
|
Death in infancy |
Occasional [Orphanet]
|
|
|
|
275 / 7739
|
|
21
|
(HPO:0000763)
|
Sensory neuropathy |
Very frequent [Orphanet]
|
|
|
|
78 / 7739
|
|
22
|
(HPO:0100543)
|
Cognitive impairment |
Very frequent [Orphanet]
|
|
|
|
230 / 7739
|