|
1
|
(HPO:0000962)
|
Hyperkeratosis |
|
|
|
|
216 / 7739
|
|
2
|
(HPO:0100725)
|
Lichenification |
|
|
|
|
14 / 7739
|
|
3
|
(OMIM)
|
Well-circumscribed peeling of the skin on the hands, feet and neck (easily elicited by moisture and minor trauma) |
|
|
|
|
1 / 7739
|
|
4
|
(OMIM)
|
Generalized dry skin with fine scaling but without erythema or blisters. (sparing of face) |
|
|
|
|
1 / 7739
|
|
5
|
(OMIM)
|
Well-circumscribed areas of nontender denuded skin on extremities |
|
|
|
|
1 / 7739
|
|
6
|
(OMIM)
|
Orthokeratosis, nonspecific basket-weave |
|
|
|
|
1 / 7739
|
|
7
|
(HPO:0000956)
|
Acanthosis nigricans |
|
|
|
|
54 / 7739
|
|
8
|
(OMIM)
|
Thickened granular zone |
|
|
|
|
1 / 7739
|
|
9
|
(OMIM)
|
Mild spongiosis |
|
|
|
|
2 / 7739
|
|
10
|
(OMIM)
|
Mild perivascular lymphocytic infiltrate in the upper dermis |
|
|
|
|
1 / 7739
|
|
11
|
(OMIM)
|
Keratin-1 (K1) staining restricted to the spinous layer |
|
|
|
|
1 / 7739
|
|
12
|
(OMIM)
|
Markedly widened intercellular spaces |
|
|
|
|
1 / 7739
|
|
13
|
(OMIM)
|
Electron-dense aggregates of keratin filaments in basal keratinocytes |
|
|
|
|
1 / 7739
|
|
14
|
(OMIM)
|
Onychodystrophy, mild, of the toenails (occasional) |
|
|
|
|
1 / 7739
|
|
15
|
(OMIM)
|
Normal |
|
|
|
|
14 / 7739
|
|
16
|
(HPO:0000007)
|
Autosomal recessive inheritance |
|
|
|
|
2538 / 7739
|
|
17
|
(HPO:0000982)
|
Palmoplantar keratoderma |
|
|
|
|
40 / 7739
|
|
18
|
(HPO:0008064)
|
Ichthyosis |
|
|
|
|
108 / 7739
|