Symptom Information: Sort according to HPO 

1
 (HPO:0001025) Urticaria Very frequent [Orphanet] 73 / 7739
2
 (HPO:0001260) Dysarthria 329 / 7739
3
 (HPO:0004337) Abnormality of amino acid metabolism Very frequent [Orphanet] 45 / 7739
4
 (HPO:0001252) Muscular hypotonia Frequent [Orphanet] 990 / 7739
5
 (HPO:0001289) Confusion 36 / 7739
6
 (HPO:0001315) Reduced tendon reflexes Frequent [Orphanet] 160 / 7739
7
 (HPO:0004322) Short stature Frequent [Orphanet] 1232 / 7739
8
 (HPO:0000988) Skin rash Very frequent [Orphanet] 98 / 7739
9
 (HPO:0100022) Abnormality of movement Frequent [Orphanet] 129 / 7739
10
 (HPO:0001263) Global developmental delay 853 / 7739
11
 (HPO:0000958) Dry skin Very frequent [Orphanet] 152 / 7739
12
 (HPO:0000639) Nystagmus Very frequent [Orphanet] 555 / 7739
13
 (HPO:0000518) Cataract Frequent [Orphanet] 454 / 7739
14
 (HPO:0000651) Diplopia Frequent [Orphanet] 37 / 7739
15
 (HPO:0001251) Ataxia 413 / 7739
16
 (HPO:0002167) Neurological speech impairment Frequent [Orphanet] 308 / 7739
17
 (HPO:0004372) Reduced consciousness/confusion Frequent [Orphanet] 73 / 7739
18
 (OMIM) No aminoaciduria or indicanuria 1 / 7739
19
 (OMIM) No tryptophan malabsorption or tryptophanuria 1 / 7739
20
 (OMIM) Impaired synthesis of quinolinic acid and nicotinamide nucleotides from tryptophan 1 / 7739
21
 (OMIM) Defect in degradation of tryptophan 1 / 7739
22
 (OMIM) Pellagra-like rash 1 / 7739
23
 (OMIM) Red, scaly rash of face, upper chest, hands, and legs 1 / 7739
24
 (HPO:0001522) Death in infancy Frequent [Orphanet] 275 / 7739
25
 (HPO:0012758) Neurodevelopmental delay Frequent [Orphanet] 949 / 7739
26
 (HPO:0000007) Autosomal recessive inheritance 2538 / 7739