|
1
|
(HPO:0000311)
|
Round face |
Very frequent [Orphanet]
|
|
|
|
104 / 7739
|
|
2
|
(HPO:0001578)
|
Hypercortisolism |
Very frequent [Orphanet]
|
|
|
|
17 / 7739
|
|
3
|
(HPO:0000938)
|
Osteopenia |
|
|
|
|
138 / 7739
|
|
4
|
(HPO:0000939)
|
Osteoporosis |
|
|
|
|
129 / 7739
|
|
5
|
(HPO:0000716)
|
Depression |
|
|
|
|
99 / 7739
|
|
6
|
(HPO:0000739)
|
Anxiety |
|
|
|
|
67 / 7739
|
|
7
|
(HPO:0000822)
|
Hypertension |
Frequent [Orphanet]
|
|
|
|
224 / 7739
|
|
8
|
(HPO:0001956)
|
Truncal obesity |
Very frequent [Orphanet]
|
|
|
|
39 / 7739
|
|
9
|
(HPO:0000978)
|
Bruising susceptibility |
Frequent [Orphanet]
|
|
|
|
123 / 7739
|
|
10
|
(HPO:0001324)
|
Muscle weakness |
Frequent [Orphanet]
|
|
|
|
859 / 7739
|
|
11
|
(HPO:0000963)
|
Thin skin |
Very frequent [Orphanet]
|
|
|
|
96 / 7739
|
|
12
|
(HPO:0002858)
|
Meningioma |
Occasional [Orphanet]
|
|
|
|
22 / 7739
|
|
13
|
(HPO:0008221)
|
Adrenal hyperplasia |
Very frequent [Orphanet]
|
|
|
|
24 / 7739
|
|
14
|
(HPO:0000819)
|
Diabetes mellitus |
Frequent [Orphanet]
|
|
|
|
131 / 7739
|
|
15
|
(HPO:0000787)
|
Nephrolithiasis |
Frequent [Orphanet]
|
|
|
|
78 / 7739
|
|
16
|
(HPO:0000709)
|
Psychosis |
|
|
|
|
61 / 7739
|
|
17
|
(HPO:0000713)
|
Agitation |
|
|
|
|
18 / 7739
|
|
18
|
(HPO:0001065)
|
Striae distensae |
|
|
|
|
26 / 7739
|
|
19
|
(HPO:0001268)
|
Mental deterioration |
|
|
|
|
88 / 7739
|
|
20
|
(HPO:0001575)
|
Mood changes |
|
|
|
|
7 / 7739
|
|
21
|
(HPO:0001579)
|
Primary hypercorticolism |
|
|
|
|
5 / 7739
|
|
22
|
(HPO:0002664)
|
Neoplasm |
|
|
|
|
111 / 7739
|
|
23
|
(HPO:0002808)
|
Kyphosis |
|
|
|
|
289 / 7739
|
|
24
|
(HPO:0002920)
|
Decreased circulating ACTH level |
|
|
|
|
3 / 7739
|
|
25
|
(HPO:0003118)
|
Increased circulating cortisol level |
|
|
|
|
3 / 7739
|
|
26
|
(HPO:0003202)
|
Skeletal muscle atrophy |
|
|
|
|
281 / 7739
|
|
27
|
(HPO:0004349)
|
Reduced bone mineral density |
Frequent [Orphanet]
|
|
|
|
165 / 7739
|
|
28
|
(HPO:0008231)
|
Macronodular adrenal hyperplasia |
|
|
|
|
2 / 7739
|
|
29
|
(OMIM)
|
No progression to cancer |
|
|
|
|
1 / 7739
|
|
30
|
(OMIM)
|
Increased serum cortisol |
|
|
|
|
3 / 7739
|
|
31
|
(OMIM)
|
Cortisol does not decrease on dexamethasone suppression test |
|
|
|
|
1 / 7739
|
|
32
|
(OMIM)
|
Decreased serum ACTH |
|
|
|
|
3 / 7739
|
|
33
|
(HPO:0100851)
|
Abnormal emotion/affect behavior |
Frequent [Orphanet]
|
|
|
|
85 / 7739
|
|
34
|
(HPO:0011362)
|
Abnormal hair quantity |
Frequent [Orphanet]
|
|
|
|
92 / 7739
|
|
35
|
(HPO:0000858)
|
Menstrual irregularities |
Frequent [Orphanet]
|
|
|
|
42 / 7739
|
|
36
|
(HPO:0004325)
|
Decreased body weight |
Very frequent [Orphanet]
|
|
|
|
492 / 7739
|
|
37
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|
|
38
|
(HPO:0003581)
|
Adult onset |
|
|
|
|
117 / 7739
|
|
39
|
(HPO:0003745)
|
Sporadic |
|
|
|
|
131 / 7739
|