|
1
|
(HPO:0000100)
|
Nephrotic syndrome |
|
|
|
|
83 / 7739
|
|
2
|
(HPO:0001744)
|
Splenomegaly |
|
|
|
|
337 / 7739
|
|
3
|
(HPO:0002240)
|
Hepatomegaly |
|
|
|
|
467 / 7739
|
|
4
|
(HPO:0002716)
|
Lymphadenopathy |
|
|
|
|
129 / 7739
|
|
5
|
(HPO:0002719)
|
Recurrent infections |
|
|
|
|
107 / 7739
|
|
6
|
(HPO:0002960)
|
Autoimmunity |
|
|
|
|
78 / 7739
|
|
7
|
(HPO:0012578)
|
Membranous nephropathy |
|
|
|
|
1 / 7739
|
|
8
|
(OMIM)
|
Renal biopsy shows deposition of IgG and complement |
|
|
|
|
1 / 7739
|
|
9
|
(OMIM)
|
Polychondritis, autoimmune |
|
|
|
|
1 / 7739
|
|
10
|
(MedDRA:10002817)
|
Antiphospholipid syndrome |
|
|
|
|
1 / 7739
|
|
11
|
(OMIM)
|
Decreased CD19+ B cells |
|
|
|
|
1 / 7739
|
|
12
|
(OMIM)
|
Decreased memory B cells |
|
|
|
|
1 / 7739
|
|
13
|
(OMIM)
|
Increased CD21+ (low) B cells |
|
|
|
|
1 / 7739
|
|
14
|
(OMIM)
|
Decreased IgG |
|
|
|
|
5 / 7739
|
|
15
|
(OMIM)
|
Autoantibodies |
|
|
|
|
2 / 7739
|
|
16
|
(OMIM)
|
Mildly decreased proliferative responses of T cells |
|
|
|
|
1 / 7739
|
|
17
|
(HPO:0000007)
|
Autosomal recessive inheritance |
|
|
|
|
2538 / 7739
|
|
18
|
(HPO:0001973)
|
Autoimmune thrombocytopenia |
|
|
|
|
18 / 7739
|
|
19
|
(HPO:0002829)
|
Arthralgia |
|
|
|
|
79 / 7739
|
|
20
|
(HPO:0003593)
|
Infantile onset |
|
|
|
|
249 / 7739
|