|
1
|
(HPO:0001257)
|
Spasticity |
|
|
|
|
251 / 7739
|
|
2
|
(HPO:0001347)
|
Hyperreflexia |
|
|
|
|
363 / 7739
|
|
3
|
(HPO:0002127)
|
Abnormal upper motor neuron morphology |
|
|
|
|
15 / 7739
|
|
4
|
(HPO:0002366)
|
Abnormal lower motor neuron morphology |
|
|
|
|
12 / 7739
|
|
5
|
(OMIM)
|
Limb muscle weakness, upper and lower |
|
|
|
|
3 / 7739
|
|
6
|
(OMIM)
|
Muscle weakness, distal, upper and lower |
|
|
|
|
1 / 7739
|
|
7
|
(OMIM)
|
Neurophysiologic studies show evidence of denervation and renervation |
|
|
|
|
1 / 7739
|
|
8
|
(OMIM)
|
Enlarged motor unit action potentials |
|
|
|
|
1 / 7739
|
|
9
|
(OMIM)
|
Normal cognition |
|
|
|
|
7 / 7739
|
|
10
|
(HPO:0000007)
|
Autosomal recessive inheritance |
|
|
|
|
2538 / 7739
|
|
11
|
(HPO:0003677)
|
Slow progression |
|
|
|
|
134 / 7739
|
|
12
|
(HPO:0007354)
|
Amyotrophic lateral sclerosis |
|
|
|
|
25 / 7739
|